We discuss best practices in scale translation and establishing measurement equivalence/ invariance (ME/I) using examples from Project 3535, a multinational work-family interface study. Best practices for scale translation and adaptation include: 1) formulating a culturally sensitive research plan and fostering team dynamics that assure its implementation, 2) use of expert bilingual and bicultural indigenous translators, 3) forward and back translation, 4) multiple rounds of review and reconciliation by a multinational team, 5) multiple rounds of pilot testing, and 6) extensive documentation of procedures. We then explain why establishing ME/I is essential for cross-cultural research and discuss different methods for how to obtain it. We describe how multiple group CFA can be used to establish three different levels of ME/I (i.e., configural, metric, and scalar). We also discuss issues such as goodness-of-fit criteria, partial invariance, and the statistical programs available for carrying out ME/I analyses.