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2 results

  • DNA syntheses in course of meiotic development in Neurospora crassa*†

  • G. A. S. Iyengar, P. C. Deka, S. C. Kundu, S. K. Sen
  • Journal:
    Genetical Research / Volume 29 / Issue 1 / February 1977
    Published online by Cambridge University Press:
    14 April 2009, pp. 1-8
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  • Nuclear DNA syntheses have been measured microspectrophotometrically in course of meiotic nuclear development in Neurospora crassa. The purpose of the study has been to establish the timing of these DNA syntheses in relation to meiosis and in the formation of its final products in an ideal genetic material, where the products of the meiotic division can be recovered and identified. Spectrophotometric analysis has indicated that the last premeiotic DNA replication is completed before caryogamy; a postmeiotic DNA replication takes place at the tetrad of the nuclei level; and finally a second postmeiotic DNA replication occurs in the ascospores to result in eight binucleated ascospores. The timing of postmeiotic replication is compatible with the models explaining gene conversion through the postulated mechanisms involving heteroduplex formation.