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4 results

  • Reviewing indications for panendoscopy in the investigation of head and neck squamous cell carcinoma

  • A Noor, L Stepan, S S-T Kao, N Dharmawardana, E H Ooi, J-C Hodge, S Krishnan, A Foreman
  • Journal:
    The Journal of Laryngology & Otology / Volume 132 / Issue 10 / October 2018
    Published online by Cambridge University Press:
    05 October 2018, pp. 901-905
    Print publication:
    October 2018
  • Background

    The role of panendoscopy in the modern investigation of head and neck cancer is changing with the development of improved radiological techniques, in-office biopsy capabilities and the low rate of synchronous primary tumours. This study aimed to review the indications for panendoscopy in the investigation of newly diagnosed head and neck cancer.

    Method

    A retrospective review was conducted of 186 patients with newly diagnosed head and neck cancer, between January 2014 and December 2015, at two tertiary centres.

    Results

    Obtaining a tissue diagnosis was the most common indication for panendoscopy (65 per cent), followed by surgical planning including transoral robotic surgery suitability assessment (22.6 per cent), and the investigation of carcinoma of an unknown primary (11.3 per cent). Two synchronous primary tumours were identified, generating a yield of 1.1 per cent.

    Conclusion

    Panendoscopy remains integral in the assessment of transoral robotic surgery suitability. Refining indications for modern panendoscopy could reduce the need for this procedure in this cohort of patients.

  • Triple primary cancers of the head and neck: case report and literature review

  • M Adams, R Caffrey
  • Journal:
    The Journal of Laryngology & Otology / Volume 128 / Issue 6 / June 2014
    Published online by Cambridge University Press:
    22 May 2014, pp. 552-554
    Print publication:
    June 2014
  • Background:

    Coincident thyroid and head and neck squamous cell carcinomas are rare. This paper presents a case of synchronous laryngeal squamous cell carcinoma, follicular thyroid carcinoma and micropapillary thyroid carcinoma.

    Methods:

    A PubMed search was performed for articles describing synchronous thyroid and head and neck squamous cell carcinomas, using the search terms ‘thyroid cancer’, ‘cancer of the head and neck’, ‘synchronous’ and ‘synchronous neoplasm’.

    Results:

    The literature suggests that the head and neck squamous cell carcinoma stage is a better predictor of outcome than the extent of surgical treatment of the thyroid gland in synchronous malignancies.

    Conclusion:

    The decision regarding surgical treatment of the thyroid in synchronous thyroid and head and neck squamous cell carcinomas should take several factors into account. The head and neck squamous cell carcinoma stage is the strongest predictor of outcome, although patient-related factors and the location of malignant thyroid tissue may also affect management.

  • A rare association of leiomyosarcoma with squamous cell carcinoma of the larynx: two cases

  • E Kara, M F Cetik, U Tuncer, A Uguz
  • Journal:
    The Journal of Laryngology & Otology / Volume 127 / Issue 8 / August 2013
    Published online by Cambridge University Press:
    07 August 2013, pp. 828-831
    Print publication:
    August 2013
  • Objective:

    To discuss the histopathogenesis and treatment choices for synchronous tumours of the larynx.

    Case reports:

    We present two cases of synchronous laryngeal leiomyosarcoma and squamous cell carcinoma. The first case was an early-stage tumour and the second an advanced-stage tumour of the larynx. Selection of adequate treatment for synchronous tumours is difficult because of different spreading rates and metastatic patterns. Treatment choices for both the primary tumour site and the neck should be related to the stage of the squamous component of the tumour.

    Conclusion:

    In such cases, the tumour location, tumour stage and lymphatic metastases must be carefully evaluated in order to make the optimum treatment choice. Treatment evaluation of the neck should be related to the stage of the squamous component of these synchronous tumours. Partial laryngectomy techniques may be preferred if the extent of the disease permits.

  • Simultaneous typical carcinoid tumour of larynx and occult papillary thyroid carcinoma

  • Z-M Lin, Y-L Chang, C-Y Lee, C-P Wang, T-Y Hsiao
  • Journal:
    The Journal of Laryngology & Otology / Volume 122 / Issue 1 / January 2008
    Published online by Cambridge University Press:
    15 March 2007, pp. 93-96
    Print publication:
    January 2008

  • Typical carcinoid tumour of the larynx is extremely rare. We report the case of a 43-year-old man initially diagnosed with typical carcinoid tumour of the larynx, presenting with a foreign body sensation in his throat. Coincidentally, an occult papillary thyroid carcinoma was diagnosed, following detection of a suspicious lymph node on pre-operative imaging studies, and confirmation by neck dissection and subsequent total thyroidectomy. Following surgery and radioiodine therapy for these cancers, the patient was alive, well and free of disease two years later. Typical carcinoid tumour of the larynx with a synchronous occult papillary thyroid carcinoma has not previously been reported. The optimal treatment strategy for this case is also discussed.