The chapter introduces key codesign principles across multiple layers of the design stack highlighting the need for cross-layer optimizations. Mitigation of various non-idealities stemming from emerging devices such as device-to-device variations, cycle-to-cycle variations, conductance drift, and stuck-at-faults through algorithm–hardware codesign are discussed. Further, inspiration from the brain’s self-repair mechanism is utilized to design neuromorphic systems capable of autonomous self-repair. Finally, an end-to-end codesign approach is outlined by exploring synergies of event-driven hardware and algorithms with event-driven sensors, thereby leveraging maximal benefits of brain-inspired computing.

The chapter focuses on the network and architecture layers of the design stack building up from device and circuit concepts introduced in Chapters 3 and 4. Architectural advantages like address-event representation stemming from neuromorphic models by leveraging spiking sparsity are discussed. Near-memory and in-memory architectures using CMOS implementations are first discussed followed by several emerging technologies, namely, correlated electron semiconductor-based devices, filamentary devices, organic devices, spintronic devices, and photonic neural networks.