Cognitive Dysfunction in Parkinson’s Disease

doi:10.1017/9781009039291.008

Chapter 7 - Cognitive Dysfunction in Parkinson’s Disease

Published online by Cambridge University Press: 05 March 2022

Damon Salzman and

Shakeel Tabish

Edited by

Néstor Gálvez-Jiménez ,

Amos D. Korczyn and

Ramón Lugo-Sanchez

Show author details

Néstor Gálvez-Jiménez: Affiliation:
Florida International University
Amos D. Korczyn: Affiliation:
Tel-Aviv University
Ramón Lugo-Sanchez: Affiliation:
Cleveland Clinic

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Summary

In 1817, the English surgeon Dr James Parkinson penned his now classic work, “An Essay on the Shaking Palsy.” He describes the condition as, “an involuntary tremulous motion, with lessened muscular power, in parts not in action, and even when supported; with a propensity to bend the trunk forwards, and to pass from a walking to a running pace; the senses and intellects being uninjured” [1].

The description of this paralysis agitans (later renamed as Parkinson’s disease by Jean Marie Charcot) has largely remained unchanged today over 200 years later. However, we now realize that the latter part, that the senses and intellect being uninjured, is incorrect. This chapter will summarize the prevalence, incidence, pathophysiology, and the scope of the cognitive changes that are seen in this disease.

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Type: Chapter
Information: Non-motor Parkinson's Disease , pp. 66 - 77

DOI: https://doi.org/10.1017/9781009039291.008 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2022

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