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Knowledge, Attitudes, and Practices Regarding Antimicrobial Use and Stewardship Among Prescribers at Acute-Care Hospitals

Published online by Cambridge University Press:  06 February 2018

Elizabeth Salsgiver ,
Daniel Bernstein ,
Matthew S. Simon ,
Daniel P. Eiras ,
William Greendyke ,
Christine J. Kubin ,
Monica Mehta ,
Brian Nelson ,
Angela Loo  and
Liz G. Ramos
...Show all authors
Elizabeth Salsgiver
Affiliation:
Weill Cornell Medicine, New York, New York
Daniel Bernstein
Affiliation:
Weill Cornell Medicine, New York, New York
Matthew S. Simon
Affiliation:
Weill Cornell Medicine, New York, New York NewYork-Presbyterian Hospital, New York, New York
Daniel P. Eiras
Affiliation:
Weill Cornell Medicine, New York, New York
William Greendyke
Affiliation:
Columbia University Medical Center, New York, New York
Christine J. Kubin
Affiliation:
NewYork-Presbyterian Hospital, New York, New York Columbia University Medical Center, New York, New York
Monica Mehta
Affiliation:
NewYork-Presbyterian Hospital, New York, New York
Brian Nelson
Affiliation:
NewYork-Presbyterian Hospital, New York, New York
Angela Loo
Affiliation:
NewYork-Presbyterian Hospital, New York, New York
Liz G. Ramos
Affiliation:
NewYork-Presbyterian Hospital, New York, New York
Haomiao Jia
Affiliation:
Columbia University Medical Center, New York, New York
Lisa Saiman
Affiliation:
NewYork-Presbyterian Hospital, New York, New York Columbia University Medical Center, New York, New York
E. Yoko Furuya
Affiliation:
NewYork-Presbyterian Hospital, New York, New York Columbia University Medical Center, New York, New York
David P. Calfee*
Affiliation:
Weill Cornell Medicine, New York, New York NewYork-Presbyterian Hospital, New York, New York
*
Address correspondence to David P. Calfee, MD, MS, Weill Cornell Medicine, 525 East 68th Street, Box 265, New York, NY 10065 (dpc9003@med.cornell.edu).
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Abstract

OBJECTIVE

To assess antimicrobial prescriber knowledge, attitudes, and practices (KAP) regarding antimicrobial stewardship (AS) and associated barriers to optimal prescribing.

DESIGN

Cross-sectional survey.

SETTING

Online survey.

PARTICIPANTS

A convenience sample of 2,900 US antimicrobial prescribers at 5 acute-care hospitals within a hospital network.

INTERVENTION

The following characteristics were assessed with an anonymous, online survey in February 2015: attitudes and practices related to antimicrobial resistance, AS programs, and institutional AS resources; antimicrobial prescribing and AS knowledge; and practices and confidence related to antimicrobial prescribing.

RESULTS

In total, 402 respondents completed the survey. Knowledge gaps were identified through case-based questions. Some respondents sometimes selected overly broad therapy for the susceptibilities given (29%) and some “usually” or “always” preferred using the most broad-spectrum empiric antimicrobials possible (32%). Nearly all (99%) reported reviewing antimicrobial appropriateness at 48–72 hours, but only 55% reported “always” doing so. Furthermore, 45% of respondents felt that they had not received adequate training regarding antimicrobial prescribing. Some respondents lacked confidence selecting empiric therapy using antibiograms (30%), interpreting susceptibility results (24%), de-escalating therapy (18%), and determining duration of therapy (31%). Postprescription review and feedback (PPRF) was the most commonly cited AS intervention (79%) with potential to improve patient care.

CONCLUSIONS

Barriers to appropriate antimicrobial selection and de-escalation of antimicrobial therapy were identified among front-line prescribers in acute-care hospitals. Prescribers desired more AS-related education and identified PPRF as the most helpful AS intervention to improve patient care. Educational interventions should be preceded by and tailored to local assessment of educational needs.

Infect Control Hosp Epidemiol 2018;39:316–322

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 39 , Issue 3 , March 2018 , pp. 316 - 322
Copyright
© 2018 by The Society for Healthcare Epidemiology of America. All rights reserved 

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Footnotes

PREVIOUS PRESENTATION. An abstract summarizing the results of this study was presented as a poster at the national conference, IDWeek 2015 on October 8, 2015 in San Diego, California (abstract #204).

References

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