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Human Sleep, Sleep Loss and Behaviour

Implications for the Prefrontal Cortex and Psychiatric Disorder

Published online by Cambridge University Press:  03 January 2018

J. A. Horne
J. A. Horne*
Affiliation:
Sleep Research Laboratory, Loughborough University, Loughborough, Leicestershire LE11 3TU
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Extract

The prefrontal cortex (PFC) consists of the cortex lying in front of the primary and secondary motor cortex, and includes the dorsolateral and orbital areas, frontal eye fields, and Broca's area. Not all of the functions of the PFC are known, but key ones are the maintenance of wakefulness and non-specific arousal, and the recruiting of various cortical areas required to deal with tasks in hand (Luria, 1973; Stuss & Benson, 1986; Fuster, 1989). Other roles include (Kolb & Whishaw, 1985) planning, sensory comparisons, discrimination, decisions for action, direction and maintenance of attention at a specific task, execution of associated scanning eye movements, and initiation and production of novel goal-directed behaviour (especially with speech). Of the senses, vision makes a particular demand of the PFC, and this is reflected by the frontal eye fields.

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The British Journal of Psychiatry , Volume 162 , Issue 3 , March 1993 , pp. 413 - 419
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Copyright © The Royal College of Psychiatrists 

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