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Multimodal Imaging in Alzheimer's Disease

The Relationship between MRI, SPECT, Cognitive and Pathological Changes

Published online by Cambridge University Press:  02 January 2018

J. A. O. Besson ,
J. R. Crawford ,
D. M. Parker ,
K. P. Ebmeier ,
P. V. Best ,
H. G. Gemmell ,
P. F. Sharp  and
F. W. Smith
J. A. O. Besson*
Affiliation:
Department of Mental Health, University of Aberdeen, Foresterhill, Aberdeen AB9 2ZD
J. R. Crawford
Affiliation:
Department of Mental Health
D. M. Parker
Affiliation:
Department of Psychology
K. P. Ebmeier
Affiliation:
Department of Mental Health, currently at MRC Brain Metabolism Unit, Royal Edinburgh Hospital, Morningside, Edinburgh
P. V. Best
Affiliation:
Department of Pathology
P. F. Sharp
Affiliation:
Department of Bio-Medical Physics, University of Aberdeen
F. W. Smith
Affiliation:
Specialist in Nuclear Medicine, Aberdeen Royal Infirmary, Foresterhill, Aberdeen
*
∗ Correspondence
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Extract

Patients with a clinical diagnosis of Alzheimer's disease were studied using MRI, SPECT, and psychometric tests. Significant correlations between focal perfusion deficits and focal cognitive deficits were found. Significant correlations between regional relaxation time of white matter and psychometric tests of diffuse and focal categories were also found. Pathological examination confirmed Alzheimer's disease as the only diagnosis.

Information

Type
Papers
Information
The British Journal of Psychiatry , Volume 157 , Issue 2 , August 1990 , pp. 216 - 220
Copyright
Copyright © Royal College of Psychiatrists, 1990 

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