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Respiratory syncytial virus as a trigger of a pulmonary hypertensive crisis after operative correction of aortic coarctation

Published online by Cambridge University Press:  26 February 2007

Jussara B. Castelli ,
Wilma T. Maeda  and
Vera D. Aiello
Jussara B. Castelli
Affiliation:
Laboratory of Pathology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil
Wilma T. Maeda
Affiliation:
Paediatric Cardiology Unit, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil
Vera D. Aiello
Affiliation:
Laboratory of Pathology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil
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Abstract

We discuss a 9-month-old male baby, submitted to surgery for correction of aortic coarctation, who showed severe bronchospasm, hypoxaemia, and cardio-respiratory arrest, and who died on the fifth postoperative day. The autopsy revealed histological signs of severe pulmonary vasoconstriction, possibly as a consequence of hypoxaemia secondary to bronchiolitis due to infection with the respiratory syncytial virus. This supposition was confirmed when viruses were detected in pulmonary tissue by immunohistochemistry and electron microscopy.

Keywords

Congenital heart diseasehypoxiacardiac postoperative outcome

Information

Type
Brief Report
Information
Cardiology in the Young , Volume 17 , Issue 2 , April 2007 , pp. 223 - 225
Copyright
© 2007 Cambridge University Press

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References

Stocker JT. The Respiratory Tract in Pediatric Pathology. J.B. Lippincott Company, Philadelphia, 1992.
Vieira SE, Stewien KE, Queiroz DAO, et al. Clinical patterns and seasonal trends in respiratory syncytial virus hospitalisations in São Paulo, Brazil. Rev Hosp Clin Fac Med S Paulo 2001; 43: 125–131.Google Scholar
Bricks LF. Prevention of respiratory syncytial virus infections. Rev Hosp Clin Fac Med S Paulo 2001; 56: 79–90.Google Scholar
Resch B, Gusenleitner W, Müller W. The impact of respiratory syncytial virus infection: a prospective study in hospitalized infants younger than 2 years. Infection 2002; 30: 193–197.Google Scholar
Welliver RC. Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. J Pediatr 2003; 143: S112–S117.Google Scholar
Haworth SG, Radley-Smith R, Yacoub M. Lung biopsy findings in transposition of the great arteries with ventricular septal defect: potentially reversible pulmonary vascular disease is not always synonymous with operability. J Am Coll Cardiol 1987; 9: 327–333.Google Scholar
Khongphatthanayothin A, Wong PC, Samara Y, et al. Impact of respiratory syncytial virus infection on surgery for congenital heart disease: postoperative course and outcome. Crit Care Med 1999; 27: 1974–1981.Google Scholar
Altman CA, Englund JA, Demmler G, et al. Respiratory syncytial virus in patients with congenital heart disease: a contemporary look at epidemiology and success of preoperative screening. Pediatr Cardiol 2000; 21: 433–438.Google Scholar