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4 - Creating and Altering Visual Percepts through Lesions and Electrical Stimulation

Published online by Cambridge University Press:  05 February 2021

Gabriel Kreiman
Affiliation:
Harvard University, Massachusetts
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Summary

We want to understand how neuronal circuits give rise to vision. We can use microelectrodes and the type of neurophysiological recordings introduced in Section 2.7. In the case of the retina, it is evident where to place the microelectrodes to examine function. However, there are about 1011 neurons in the human brain, and we do not have any tools that enable us to record from all of them. How do we figure out what parts of the brain are relevant for vision so we can study them at the neurophysiological level?

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Further Reading

Boyden, E. S.; Zhang, F.; Bamberg, E.; Nagel, G.; and Deisseroth, K. (2005). Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuroscience 8: 12631268.CrossRefGoogle ScholarPubMed
Penfield, W. (1958). Some mechanisms of consciousness discovered during electrical stimulation of the brain. Proceedings of the National Academy of Sciences of the United States of America 44: 5166.Google Scholar
Sacks, O. (1995). An anthropologist on Mars. New York: Alfred A. Knopf.Google Scholar
Sperry, R. (1982). Some effects of disconnecting the cerebral hemispheres. Science 217: 12231226.CrossRefGoogle ScholarPubMed
Ungerleider, L.; and Mishkin, M. (1982). Two cortical visual systems. In Analysis of Visual Behavior, ed. Ingle, D., Goodale, M., and Mansfield, R.. Cambridge: MIT Press.Google Scholar

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