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  • Print publication year: 2011
  • Online publication date: May 2011

Case 19 - Hypersexuality in a 69-year-old man


This chapter talks about a 61-year-old woman with a 5-year history of difficulty finding words and slowly progressive memory decline. At initial presentation, mood was good. General neurological exam was unremarkable. Language examination showed that spontaneous speech was fluent. Single photon emission computed tomography (SPECT) revealed reduced cortical perfusion in the left frontal, parietal, and temporal lobes compared to the right. The initial clinical impression was semantic dementia (SD). This senile dementia comprises one of the three clinical presentations of primary progressive aphasia (PPA). The other two are progressive non-fluent aphasia (PNFA) and logopenic progressive aphasia. PPA has been recognized under several different labels and concepts over the last century. The term SD was coined in 1989 to describe three patients with fluent aphasia, impaired word comprehension and visual comprehension deficits. SD shows insidious onset and gradual progression that is characterized by understanding of word meaning and/or object identity.

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