The aim of this chapter is to apply the book’s general organizing principle and method to some of the most significant developments in the English-speaking Protestant world in the last four centuries, including the transition from pietism to evangelicalism, the explosive growth of Protestant missions, the origins of premillennial dispensationalism and its contribution to the rise of American fundamentalism, and finally the worldwide spread of Pentecostalism. None of these developments in the creation of a “Protestant International” can be studied within a single denominational or national tradition, and none can be understood without coming to terms with its nucleus of ideas/theologies, the nodal points of transmission and dissemination, and the transnational networks that facilitated growth.