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Chapter 10 - Epilepsy as a Complex Network Disorder

Insights from Functional MRI

Published online by Cambridge University Press:  06 January 2023

By
David Carmichael ,
Rory J. Piper  and
Fraser Aitken
Edited by
Rod C. Scott  and
J. Matthew Mahoney
Rod C. Scott
Affiliation:
University of Vermont
J. Matthew Mahoney
Affiliation:
University of Vermont
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Summary

Functional magnetic resonance imaging (fMRI) was conceived in the early 1990s due to the coincidence of two advances: (1) MRI scanner technology able to support fast echo-planar imaging imaging techniques with the required temporal stability and (2) the scientific knowledge that differences in the magnetic susceptibility of blood may be associated with MRI signal changes based on alterations in blood oxygenation levels. These elements, together with the assumption that changes in blood oxygenation and volume would accompany changes in neural activity in the brain, motivated research groups around the world to develop fMRI.

Type
Chapter
Information
A Complex Systems Approach to Epilepsy
Concept, Practice, and Therapy
 , pp. 135 - 152
Publisher: Cambridge University Press
Print publication year: 2023

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