In 2012, at age 64, Anne desired to retire. She didn’t want to serve past her prime. If she retired, her lab space could go instead to a young investigator just starting a career. Anne was pleased with the search committee’s replacement – Merit Cudkowicz – a woman on Anne’s faculty who had established and directed their Program in Clinical Investigation. Her area of expertise was amyotrophic lateral sclerosis (ALS). She had also come down to Venezuela one year to work on the project. She went from ‘bench to bedside’ by assessing potential new therapies discovered at the laboratory bench in humans using the best clinical trial designs. To celebrate completing 21 years of service, Anne organized a trip to the Galapagos. She found an outfit with a boat and invited 20 of her best friends to go on the trip, including Nancy, her sister Alice, David Housman and his wife, Gill Bates and her husband, Alice Flaherty and her family, Anne’s daughter Ellen and her boyfriend and others. Anne became chair of the Scientific Advisory Board of Nancy’s HDF, which entailed assigning grant reviewers, reviewing grants and running meetings. She was appointed chair of the Scientific Advisory Board of the Collaborative Center for XDP.