This chapter uses the events of 9/11 in two ways. In a general sense we use 9/11 as a temporal benchmark in the same way as we used the ending of the Cold War. In a more specific sense, we ask whether 9/11 and the subsequent unfolding ‘Global War on Terrorism’ (GWoT) have been taken as an ‘event’ of sufficient importance to reshape the agenda of ISS in some ways. How did the different strands within ISS respond (or not) to all this, and what do their responses tell us about the sub-field as it moves deeper into the twenty-first century? We should bear in mind that chapter 7 dealt with those theoretical and conceptual discussions in the widening and deepening wing of ISS that were carried over from the 1990s and into the post-9/11 era and which proceeded relatively unaffected by the attacks and the ensuing GWoT. Thus we begin this chapter from the partial conclusion that not all of ISS changed pace and direction in response to these events. Still, there are important analytical as well as political reasons for asking whether and how the field of ISS was impacted by the GWoT. Analytically, this tells us something about the extent to which ISS is driven by events, a sociology of science debate laid out in chapter 3. Politically, the GWoT has had important consequences for the relationship between ‘the West and the rest’ as well as for a number of domestic policies in the US and Europe.