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  3. Imaging Dopamine
  • Cited by 15
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    • Publisher:
      Cambridge University Press
      Publication date:
      04 December 2009
      02 April 2009
      ISBN:
      9780511575853
      9780521790024
      DOI:
      https://doi.org/10.1017/CBO9780511575853
      Dimensions:
      (247 x 174 mm)
      Weight & Pages:
      0.88kg, 356 Pages
      Dimensions:
      Weight & Pages:
      • Subjects:
      Life Sciences, Neurosciences, Molecular Biology, Biochemistry, and Structural Biology
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    Subjects:
    Life Sciences, Neurosciences, Molecular Biology, Biochemistry, and Structural Biology
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    Book description

    Since its discovery 50 years ago, brain dopamine has been implicated in the control of movement and cognition, and is concerned with diverse brain diseases such as Parkinson's disease, schizophrenia and drug addiction. This book is an illustrated biography of the dopamine molecule, from its synthesis in the brain to its signalling mechanisms and ultimately to its metabolic breakdown. Using colour illustrations of positron emission tomography (PET) scans, each chapter presents a specific stage in the biochemical pathway for dopamine. Writing for researchers and graduate students, Paul Cumming presents a compilation of all that has been learned about dopamine through molecular imaging, a technology which allows the measurement of formerly invisible processes in the living brain. He reviews current technical controversies in the interpretation of dopamine imaging, and presents key results illuminating brain dopamine in illness and health.

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