Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-45l2p Total loading time: 0 Render date: 2024-04-26T10:30:50.890Z Has data issue: false hasContentIssue false

Chapter 22 - Pre-eclampsia

from Section 8 - Microangiopathies

Published online by Cambridge University Press:  01 February 2018

Sue Pavord
Affiliation:
University of Oxford
Beverley Hunt
Affiliation:
King's College London
Get access
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kuklina, EV, Ayala, C, Callaghan, WM. Hypertensive disorders and severe obstetric morbidity in the United States. Obstetrics and Gynecology 2009; 113: 12991306.Google Scholar
World Health Organization. Maternal Mortality in 2005: Estimates Developed by WHO, UNICEF, UNIFPA and the World Bank. Geneva, World Health Organization; 2007.Google Scholar
RCOG. The Investigation and Management of the Small-for-Gestational Age Fetus. Green-Top Guideline No. 31, 2nd Edition. London: Royal College of Obstetricians and Gynaecologists; 2013, Minor revisions – January 2014.Google Scholar
Bhide, A, Rana, R, Dhavilkar, M et al. The value of the urinary protein: creatinine ratio for the detection of significant proteinuria in women with suspected preeclampsia. Acta Obstetricia et Gynecologica Scandinavica 2015; 94(5): 542546.CrossRefGoogle ScholarPubMed
Roberts, JM, Gammill, HS. Preeclampsia: recent insights. Hypertension 2005; 46: 12431249.Google Scholar
Maynard, SE, Min, JY, Mercham, J et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt-1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. Journal of Clinical Investigations 2003; 111: 649658.Google Scholar
Lu, F, Longo, M, Tamayo, E et al. The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice. American Journal of Obstetrics and Gynecology 2007; 196: 396.CrossRefGoogle ScholarPubMed
Li, B, Ogasawara, AK, Yang, R et al. KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF. Hypertension 2002; 39: 10951100.CrossRefGoogle ScholarPubMed
Gilbert, JS, Babcock, SA, Granger, JP. Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression. Hypertension 2007; 50: 11421147.CrossRefGoogle ScholarPubMed
Levine, RJ, Lam, C, Qian, C et al. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. New England Journal of Medicine 2006; 355: 9921005.CrossRefGoogle ScholarPubMed
Venkatesha, S, Toporsian, M, Lam, C et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nature Medicine 2006; 12: 642649.Google Scholar
Masuyama, H, Nakatsukasa, H, Takamoto, N, Hiramatsu, Y. Correlation between soluble endoglin, vascular endothelial growth factor receptor-1 and adipocytokines in preeclampsia. Journal of Clinical and Endocrinological Metabolism 2007; 92: 26722679.CrossRefGoogle ScholarPubMed
Redman, CW, Sacks, GP, Sargent, IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. American Journal of Obstetrics and Gynecology 1999; 180: 499506.CrossRefGoogle ScholarPubMed
Alijotas-Reig, J, Palacio-Garcia, C, Llurba, E, Vilardell-Tarres, M. Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review. Fertility and Sterility 2013; 99(2): 441449. doi: 10.1016/j.fertnstert.2012.10.009. Epub 2012 Nov 2.Google Scholar
Irgens, HU, Reiseter, L, Irgens, LM, Lie, RT. Long-term mortality of mothers and fathers after pre-eclampsia: population based cohort study. British Medical Journal 2001; 323: 12131217.Google Scholar
Barker, DJB (ed.) Foetal and Infant Origins of Adult Disease. London: BMJ Publishing Group; 1992.Google Scholar
Magnussen, EB, Vatlen, LJ, Lund-Nilsen, et al. Pregnancy cardiovascular risk factors as predictors of pre-eclampsia: population based cohort study. British Medical Journal 2007; 225: 978981.CrossRefGoogle Scholar
Berends, AL, de Groot, CJM, Sijbrands, EJ et al. Shared constitutional risks for maternal vascular-related pregnancy complications and future cardiovascular disease. Hypertension 2008; 51: 10341041.Google Scholar
Aykas, F, Solak, Y, Erden, A et al. Persistence of cardiovascular risk factors in women with previous preeclampsia: a long-term follow-up study. Journal of Investigative Medicine 2015; 63(4): 641645.CrossRefGoogle ScholarPubMed
Liu, X, Olsen, J, Agerbo, E et al. Maternal preeclampsia and childhood asthma in the offspring. Pediatric Allergy and Immunology 2015; 26(2): 181185. doi: 10.1111/pai.12344.Google Scholar
Walker, CK, Krakowiak, P, Baker, A et al. Preeclampsia, placental insufficiency, and autism spectrum disorder or developmental delay. JAMA Pediatrics 2015; 169(2): 154162.CrossRefGoogle ScholarPubMed
Rasmussen, S, Irgens, LM. History of fetal growth restriction is more strongly associated with severe rather than milder pregnancy-induced hypertension. Hypertension 2008; 51: 12311238.CrossRefGoogle ScholarPubMed
Huppetz, B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 2008; 51: 970975.CrossRefGoogle Scholar
Sood, R, Kalloway, S, Mast, AE, Hilard, CJ, Weiler, H. Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells. Blood 2006; 107(8): 31733181.Google Scholar
Song, J, Li, Y, An, RF. Identification of early-onset preeclampsia-related genes and microRNAs by bioinformatics approaches. Reproductive Sciences 2015; 22(8):954963.Google Scholar
Salmon, JE, Heuser, C, Triebwasser, M et al. Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort. PLoS Medicine 2011; 8(3): e1001013.Google Scholar
Dekker, GA, de Vries, JI, Doelitzsch, PM, Huijgens, PC, von Blomberg, BM, Jakobs, C, van Geijn, HP. Underlying disorders associated with severe early-onset preeclampsia. American Journal of Obstetrics and Gynecology 1995; 173(4): 10421048.Google Scholar
Papageorgiou, AT, Yu, CK, Bindra, R, Pandis, G, Nicolaides, KH. Multicenter screening for pre-eclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks’ of gestation. Ultrasound Obstetrics and Gynecology 2001; 18: 441449.Google Scholar
Chappell, LC, Seed, PT, Briley, A et al. A longitudinal study of biochemical variables in women at risk of preeclampsia. American Journal of Obstetrics and Gynecology 2002; 187: 127136.Google Scholar
Hund, M, Allegranza, D, Schoedl, M et al. Multicenter prospective clinical study to evaluate the prediction of short-term outcome in pregnant women with suspected preeclampsia (PROGNOSIS): study protocol. BMC Pregnancy Childbirth 2014; 14: 324. doi: 10.1186/1471–2393-14–324.CrossRefGoogle ScholarPubMed
Palomaki, GE, Haddow, JE, Haddow, HR et al. Modeling risk for severe adverse outcomes using angiogenic factor measurements in women with suspected preterm preeclampsia. Prenatal Diagnosis 2015; 35(4): 386393. doi: 10.1002/pd.4554.Google Scholar
CLASP. A randomised trial of low dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women. CLASP (Collaborative low dose Aspirin Study in Pregnancy) Collaborative Group. The Lancet 1994; 343: 619629.Google Scholar
Askie, LM, Duley, L, Henderson-Smart, DJ, Stewart, LA. PARIS Collaborative Group. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. The Lancet 2007; 369: 17911798.Google Scholar
Askie, L, Duley, L, Henderson-Smart, D, Stewart, L. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. The Lancet 2007; 369: 17911798.Google Scholar
Bates, SM, Greer, IA, Middeldorp, S, Veenstra, DL, Prabulos, AM, Vandvik, PO. VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141 (2 Suppl): e691Se736S.Google Scholar
Moore, GS, Allshouse, AA, Post, AL, Galan, HL, Heyborne, KD. Early initiation of low-dose aspirin for reduction in preeclampsia risk in high-risk women: a secondary analysis of the MFMU High-Risk Aspirin Study. Journal of Perinatology 2015; 35(5): 328331. doi: 10.1038/jp.2014.214Google Scholar
Li, C, Raikwar, NS, Santillan, MK, Santillan, DA, Thomas, CP. Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1. Placenta 2015; 36(4): 446453.CrossRefGoogle ScholarPubMed
Mello, G, Parretti, E, Fatini, C et al. Low-molecular-weight heparin lowers the recurrence rate of preeclampsia and restores the physiological vascular changes in angiotensin-converting enzyme DD women. Hypertension 2005; 45: 8691.CrossRefGoogle ScholarPubMed
Maki, M, Kobayashi, T, Terao, T et al. Antithrombin therapy for severe preeclampsia: results of a double-blind, randomized, placebo-controlled trial. BI51.017 Study Group. Thrombosis and Hemostasis 2000; 84: 583590.Google Scholar
International Clinical Trials Registry Platform. Statins to Ameliorate early onset Pre-eclampsia StAMP. 10. ISRCTN Register; 2009. http://www.controlled-trials.com/ISRCTN23410175 (accessed December 2013).Google Scholar
Costantine, MM, Cleary, K; Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetric–Fetal Pharmacology Research Units Network. Pravastatin for the prevention of preeclampsia in high-risk pregnant women. Obstetrics and Gynecology 2013; 121(2 p. 1): 349353.CrossRefGoogle ScholarPubMed
Bateman, BT, Hernandez-Diaz, S, Fischer, MA et al. Statins and congenital malformations: cohort study. BMJ 2015; 350: h1035.Google Scholar
Kakigano, A, Tomimatsu, T, Mimura, K et al. Drug repositioning for preeclampsia therapeutics by in vitro screening: phosphodiesterase-5 inhibitor vardenafil restores endothelial dysfunction via induction of placental growth factor. Reproductive Sciences 2015; 22(10): 12721280.CrossRefGoogle ScholarPubMed
Doyle, LW, Crowther, CA, Middleton, P et al. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus. Cochrane Database of Systematic Reviews 2009; 1: CD004661.Google Scholar
McCoy, S, Baldwin, K. Pharmacotherapeutic options for the treatment of preeclampsia. American Journal Health-System Pharmacy 2009; 66: 337344.CrossRefGoogle ScholarPubMed
Woudstra, DM, Chandra, S, Hofmeyr, GJ, Dowswell, T. Corticosteroids for HELLP syndrome in pregnancy. Cochrane Database of Systematic Reviews 2010; (9): CD008148.Google Scholar
Mao, M, Chen, C. Corticosteroid therapy for management of hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome: A meta-analysis. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2015; 21: 37773783.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×