Pre-eclampsia: Etiology and Clinical Practice

doi:10.1017/CBO9780511545634

Pre-eclampsia is one of the leading causes of death and disability in mothers and babies. Over four million women worldwide will develop the disorder every year. This book, written by an international team of experts, focuses on both the scientific basis of pre-eclampsia and its management. The basic science section contains reviews of the most exciting research developments in pre-eclampsia. The clinical chapters provide a comprehensive review of the pertinent literature, highlighting data and ideas or developments in management. There is a section in each chapter (where relevant) that deals with practical management, giving clinicians a formulated treatment plan that they can implement directly. The book was originally published in 2007, and will have continuing relevance for all professionals interested in the reproductive sciences, and to obstetricians and physicians with an interest in pre-eclampsia.

' … anyone whose clinical or research work involves pre-eclampsia should find this book a valuable resource,.'

Source: The Obstetrician and Gynaecologist

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Contents

Frontmatter
pp i-vi
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Contents
pp vii-x
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List of contributors
pp xi-xvi
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Preface
pp xvii-xviii
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Part I - Basic science
pp 1-2
- By Fiona Lyall, Michael Belfort
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1 - Trophoblast invasion in pre-eclampsia and other pregnancy disorders
pp 3-19
- By Robert Pijnenborg, Lisbeth Vercruysse, Myriam Hanssens, F. André Van Assche
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2 - Development of the utero-placental circulation: purported mechanisms for cytotrophoblast invasion in normal pregnancy and pre-eclampsia
pp 20-36
- By Fiona Lyall
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3 - In vitro models for studying pre-eclampsia
pp 37-49
- By John D. Aplin, Ian P. Crocker
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4 - Endothelial factors
pp 50-77
- By Mona Noori, Mina Savvidou, David Williams
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5 - The renin–angiotensin system in pre-eclampsia
pp 78-91
- By Fiona Broughton Pipkin
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6 - Immunological factors and placentation: implications for pre-eclampsia
pp 92-102
- By Ashley Moffett, Susan E. Hiby
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7 - Immunological factors and placentation: implications for pre-eclampsia
pp 103-120
- By C. W. G. Redman, I. L. Sargent
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8 - The role of oxidative stress in pre-eclampsia
pp 121-137
- By M. T. M. Raijmakers, L. Poston
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9 - Placental hypoxia, hyperoxia and ischemia–reperfusion injury in pre-eclampsia
pp 138-151
- By Graham J. Burton, Tai-Ho Hung, Eric Jauniaux
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10 - Tenney–Parker changes and apoptotic versus necrotic shedding of trophoblast in normal pregnancy and pre-eclampsia
pp 152-163
- By Peter Kaufmann, Berthold Huppertz
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11 - Dyslipidemia and pre-eclampsia
pp 164-182
- By Carl A. Hubel
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12 - Pre-eclampsia a two-stage disorder: what is the linkage? Are there directed fetal/placental signals?
pp 183-194
- By Jim Roberts
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13 - High altitude and pre-eclampsia
pp 195-208
- By Stacy Zamudio
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14 - The use of mouse models to explore fetal–maternal interactions underlying pre-eclampsia
pp 209-214
- By James C. Cross
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15 - Prediction of pre-eclampsia
pp 215-231
- By Leslie Myatt, Lavenia B. Carpenter
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16 - Long-term implications of pre-eclampsia for maternal health
pp 232-240
- By Gordon C. S. Smith
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Part II - Clinical Practice
pp 241-242
- By Fiona Lyall, Michael Belfort
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17 - Classification and diagnosis of pre-eclampsia
pp 243-257
- By Robyn. A. North
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18 - Measuring blood pressure in pregnancy and pre-eclampsia
pp 258-275
- By Andrew H. Shennan, Annemarie De Greeff
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19 - Immune maladaptation in the etiology of pre-eclampsia; an updated epidemiological perspective
pp 276-294
- By Gus Dekker, Pierre Yves Robillard
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20 - Genetics of pre-eclampsia and counseling the patient who developed pre-eclampsia
pp 295-304
- By Kenneth Ward
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21 - Thrombophilias and pre-eclampsia
pp 305-324
- By Isobel D. Walker
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22 - Medical illness and the risk of pre-eclampsia
pp 325-338
- By Catherine Nelson-Piercy
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23 - The kidney and pre-eclampsia
pp 339-356
- By M. C. Smith, J. M. Davison
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24 - Management of mild pre-eclampsia
pp 357-368
- By Tracey Glanville, James J. Walker
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Etiology and Clinical Practice

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