Published online by Cambridge University Press: 27 May 2021
Mr. Smith is a 68-year-old man with chronic obstructive lung disease on supplemental oxygen who presented to the emergency department with influenza A and a Staphylococcus aureus superinfection. The patient was admitted to the intensive care unit (ICU) and underwent endotracheal intubation with mechanical ventilation for acute respiratory distress syndrome. After 10 days of appropriate antibiotics, Mr. Smith’s respiratory status has significantly improved. He is now requiring minimal support from the ventilator with an FiO2 of 40% and 5 cmH20 of positive end-expiratory pressure. Unfortunately, he has repeatedly failed daily spontaneous breathing trials. Due to his prolonged ICU course, he is physically deconditioned and now dependent on mechanical ventilation.
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