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Chapter 17 - A Bun in the Oven

How to Use TIVA in Obstetrics

Published online by Cambridge University Press:  18 November 2019

By
Pamela Flood  and
Jessica Ansari
Edited by
Michael G. Irwin ,
Gordon T. C. Wong  and
Shuk Wan Lam
Michael G. Irwin
Affiliation:
The University of Hong Kong
Gordon T. C. Wong
Affiliation:
The University of Hong Kong
Shuk Wan Lam
Affiliation:
The University of Hong Kong
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Summary

The physiological changes of pregnancy result in significant changes to the PK and PD properties of drugs commonly used with TIVA; and drug effects on the fetus and the uterus are important determinants as to whether TIVA is the optimal anaesthetic technique for a given procedure. Also, some drugs used in TIVA have unique roles in labour analgesia in addition to surgical anaesthesia. However, it is important to realise that despite widespread use of these medications in pregnant patients, research data is limited. Many drugs are used off label in pregnancy and the contemporary regulatory milieu can make robust studies challenging, if not impossible, to perform. Nonetheless, the significant clinical experience with these medications over the years in many countries supports a useful and practical perspective of the role of these drugs in pregnancy.

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Type
Chapter
Information
Taking on TIVA
Debunking Myths and Dispelling Misunderstandings
 , pp. 139 - 145
Publisher: Cambridge University Press
Print publication year: 2019

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