Women's Aging and Depression

doi:10.1017/CBO9780511841262.008

6 - Women's Aging and Depression

Published online by Cambridge University Press: 05 June 2012

Brenda W. J. H. Penninx

Edited by

Corey L. M. Keyes and

Sherryl H. Goodman

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Brenda W. J. H. Penninx: Affiliation:
Sticht Center on Aging, Wake Forest University, Wake Forest, North Carolina, Department of Psychiatry, Vrije Universiteit, Amsterdam, The Netherlands
Corey L. M. Keyes: Affiliation:
Emory University, Atlanta
Sherryl H. Goodman: Affiliation:
Emory University, Atlanta

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Summary

Population aging is a worldwide phenomenon. The oldest of the old, persons aged 85 years and older, comprise the fastest growing segment of the aged. Since the life expectancy has consistently been higher for women than for men, the elderly population is composed of more women than men. So, in absolute terms, aging is affecting women more than men. Among persons aged 65 years and older in the United States, almost 60% are women. The proportion of women in the older populations climbs with age to over 70% in those aged 85 years and older. This trend can be observed across the developed world, where women typically outlive men by 5 to 9 years. This chapter describes the extent of depression experienced in women and men in old age. Subsequently, important biological, physical, and psychosocial risk factors for depression in older women will be described. The chapter will finish with describing the physical consequences of late-life depression in women.

PREVALENCE OF DEPRESSION IN OLDER WOMEN AND MEN

Major depression (also called major depressive disorder) is diagnosed in the Diagnostic and Statistical Manual of the American Psychiatric Association (American Psychiatric Association, 1989) when a person exhibits five or more out of the following nine symptoms: depressed mood, lack of interest, feelings of worthlessness or inappropriate guilt, diminished ability to concentrate or make decisions, fatigue, psychomotor agitation or retardation, insomnia or hypersomnia, significant decrease or increase in weight or appetite, and recurrent thoughts of death or suicidal ideation.

Type: Chapter
Information: Women and Depression
A Handbook for the Social, Behavioral, and Biomedical Sciences
, pp. 129 - 144

DOI: https://doi.org/10.1017/CBO9780511841262.008 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2006

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References

American Psychiatric Association. (1989). Diagnostic and statistical manual of mental disorders (3rd ed.), Washington, DC

Anda, R. F., Williamson, D. F., Escobedo, L. G., Mast, E. E., Giovino, G. A., & Remington, P. L. (1990). Depression and the dynamics of smoking. A national perspective. Journal of the American Medical Association, 264, 1541–1545CrossRef Google Scholar PubMed

Arborelius, L., Owens, M. J., Plotsky, P. M., & Nemeroff, C. B. (1999). The role of corticotropin-releasing factor in depression and anxiety disorders. Journal of Endocrinology, 160, 1–12CrossRef Google Scholar PubMed

Beekman, A. T., Copeland, J. R., & Prince, M. J. (1999). Review of community prevalence of depression in later life. British Journal of Psychiatry, 174, 307–311CrossRef Google Scholar PubMed

Beekman, A. T., Deeg, D. J., Tilburg, T., Smit, J. H., Hooijer, C., & Tilburg, W. (1995). Major and minor depression in later life: A study of prevalence and risk factors. Journal of Affective Disorders, 36, 65–75CrossRef Google Scholar PubMed

Blazer, D., Burchett, B., Service, C., & George, L. K. (1991). The association of age and depression among the elderly: An epidemiologic exploration. Journal of Gerontology Medical Sciences, 46, M210–M215CrossRef Google Scholar PubMed

Comijs, H. C., Jonker, C., Beekman, A. T., & Deeg, D. J. (2001). The association between depressive symptoms and cognitive decline in community-dwelling elderly persons. International Journal of Geriatric Psychiatry, 16, 361–367CrossRef Google Scholar PubMed

Davis, K. L., Davis, B. M., Mathe, A. A., Mohs, R. C., Rothpearl, A. B., Levy, M. I.. (1984). Age and the dexamethasone suppression test in depression. American Journal of Psychiatry, 141, 872–874Google Scholar PubMed

Fonda, S. J., Wallace, R. B., & Herzog, A. R. (2001). Changes in driving patterns and worsening depressive symptoms among older adults. Journal of Gerontology of Social Science, 56 S343–S351CrossRef Google Scholar PubMed

Frasure-Smith, N., Lesperance, F., & Talajic, M. (1993). Depression following myocardial infarction. Impact on 6-month survival. Journal of the American Medical Association, 270, 1819–1825CrossRef Google Scholar PubMed

Gatz, M., Pedersen, N. L., Plomin, R., Nesselroade, J. R., & McClearn, G. E. (1992). Importance of shared genes and shared environments for symptoms of depression in older adults. Journal of Abnormal Psychology, 101, 701–708CrossRef Google Scholar PubMed

Jansson, M., Gatz, M., Berg, S., Johansson, B., Malmberg, B., McClearn, G. E.. (2004). Gender differences in heritability of depressive symptoms in the elderly. Psychological Medicine, 34, 471–479CrossRef Google Scholar PubMed

Johnson, W., McGue, M., Gaist, D., Vaupel, J. W., & Christensen, K. (2002). Frequency and heritability of depression symptomatology in the second half of life: Evidence from Danish twins over 45. Psychological Medicine, 32, 1175–1185CrossRef Google Scholar PubMed

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R.. (2003). The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R). Journal of the American Medical Association, 289, 3095–3105CrossRef Google Scholar

Kraaij, V., Arensman, E., & Spinhoven, P. (2002). Negative life events and depression in elderly persons: A meta-analysis. Journal of Gerontology Social Sciences and Medicine, 57, 87–94CrossRef Google Scholar PubMed

Kumar, A., Thomas, A., Lavretsky, H., Yue, K., Huda, A., Curran, J.. (2002). Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy. American Journal of Psychiatry, 159, 630–636CrossRef Google Scholar PubMed

Lewinsohn, P. M., Rohde, P., Seeley, J. R., & Fischer, S. A. (1991). Age and depression: Unique and shared effects. Psychology and Aging, 6, 247–260CrossRef Google Scholar PubMed

McGue, M., & Christensen, K. (1997). Genetic and environmental contributions to depression symptomatology: Evidence from Danish twins 75 years of age and older. Journal of Abnormal Psychology, 106, 439–448CrossRef Google Scholar PubMed

National Center for Health Statistics (2001). Death rates for 72 selected causes by 5-year age groups, race and sex: United States, 1979–1998. Washingon DC

Ormel, J., Kempen, G. I., Penninx, B. W., Brilman, E. I., Beekman, A. T., & Sonderen, E. (1997). Chronic medical conditions and mental health in older people: disability and psychosocial resources mediate specific mental health effects. Psychological Medicine, 27, 1065–1077CrossRef Google Scholar PubMed

Penninx, B. W., Beekman, A. T., Honig, A., Deeg, D. J., Schoevers, R. A., Eijk, J. T.. (2001). Depression and cardiac mortality: Results from a community-based longitudinal study. Archives of General Psychiatry, 58, 221–227CrossRef Google Scholar PubMed

Penninx, B. W., Beekman, A. T., Ormel, J., Kriegsman, D. M., Boeke, A. J., Eijk, J. T.. (1996). Psychological status among elderly people with chronic diseases: does type of disease play a part? Journal of Psychosomatric Research, 40, 521–534CrossRef Google Scholar PubMed

Penninx, B. W., Guralnik, J. M., Ferrucci, L., Fried, L. P., Allen, R. H., & Stabler, S. P. (2000). Vitamin B(12) deficiency and depression in physically disabled older women: Epidemiologic evidence from the Women's Health and Aging Study. American Journal of Psychiatry, 157, 715–721CrossRef Google Scholar PubMed

Penninx, B. W., Guralnik, J. M., Ferrucci, L., Simonsick, E. M., Deeg, D. J., & Wallace, R. B. (1998). Depressive symptoms and physical decline in community-dwelling older persons. Journal of the American Medical Association, 279, 1720–1726CrossRef Google Scholar PubMed

Penninx, B. W., Leveille, S., Ferrucci, L., Eijk, J. T., & Guralnik, J. M. (1999). Exploring the effect of depression on physical disability: Longitudinal evidence from the established populations for epidemiologic studies of the elderly. American Journal of Public Health, 89, 1346–1352CrossRef Google Scholar PubMed

Penninx, B. W., Rejeski, W. J., Pandya, J., Miller, M. E., Di Bari, M., Applegate, W. B.. (2002). Exercise and depressive symptoms: A comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology. Journal of Gerontology: Psychological Sciences, 57, 124–132CrossRef Google Scholar PubMed

Prabhakaran, P., & Butler, R. (2002). What are older peoples' experiences of taking antidepressants? Journal of Affective Disorders, 70, 319–322CrossRef Google Scholar PubMed

Roberts, S. B., & Kendler, K. S. (1999). Neuroticism and self-esteem as indices of the vulnerability to major depression in women. Psychological Medicine, 29, 1101–1109CrossRef Google Scholar PubMed

Schulz, R., Drayer, R. A., & Rollman, B. L. (2002). Depression as a risk factor for non-suicide mortality in the elderly. Biological Psychiatry, 52, 205–225CrossRef Google Scholar PubMed

Seidman, S. N., Araujo, A. B., Roose, S. P., & McKinlay, J. B. (2001). Testosterone level, androgen receptor polymorphism, and depressive symptoms in middle-aged men. Biological Psychiatry, 50, 371–376CrossRef Google Scholar PubMed

Sevick, M. A., Rolih, C., & Pahor, M. (2000). Gender differences in morbidity and mortality related to depression: A review of the literature. Aging (Milano.), 12, 407–416Google Scholar PubMed

Gool, C. H., Kempen, G. I., Penninx, B. W., Deeg, D. J., Beekman, A. T., & Eijk, J. T. (2003). Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons: Results from the Longitudinal Aging Study Amsterdam. Age and Aging, 32, 81–87CrossRef Google Scholar PubMed

Whooley, M. A., Kip, K. E., Cauley, J. A., Ensrud, K. E., Nevitt, M. C., & Browner, W. S. (1999). Depression, falls, and risk of fracture in older women. Study of Osteoporotic Fractures Research Group. Archives of Internal Medicine, 159, 484–490CrossRef Google Scholar PubMed

Wulsin, L. R., & Singal, B. M. (2003). Do depressive symptoms increase the risk for the onset of coronary disease? A systematic quantitative review. Psychosomatric Medicine, 65, 201–210CrossRef Google Scholar PubMed

Yaffe, K., Ettinger, B., Pressman, A., Seeley, D., Whooley, M., Schaefer, C.. (1998). Neuropsychiatric function and dehydroepiandrosterone sulfate in elderly women: a prospective study. Biological Psychiatry, 43, 694–700CrossRef Google Scholar PubMed

Yaffe, K., Lui, L. Y., Grady, D., Cauley, J., Kramer, J., & Cummings, S. R. (2000). Cognitive decline in women in relation to non-protein-bound oestradiol concentrations. Lancet, 356, 708–712CrossRef Google Scholar PubMed