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    Htun, A. Sato, T. and Hanada, M. 2016. Effect of difructose anhydride III supplementation on passive immunoglobulin G transfer and serum immunoglobulin G concentration in newborn Holstein calves fed pooled colostrum. Journal of Dairy Science, Vol. 99, Issue. 7, p. 5701.


    Short, D.M. Moore, D.A. and Sischo, W.M. 2016. A Randomized Clinical Trial Evaluating the Effects of Oligosaccharides on Transfer of Passive Immunity in Neonatal Dairy Calves. Journal of Veterinary Internal Medicine, Vol. 30, Issue. 4, p. 1381.


    Brady, M.P. Godden, S.M. and Haines, D.M. 2015. Supplementing fresh bovine colostrum with gut-active carbohydrates reduces passive transfer of immunoglobulin G in Holstein dairy calves. Journal of Dairy Science, Vol. 98, Issue. 9, p. 6415.


    Spring, P. Wenk, C. Connolly, A. and Kiers, A. 2015. A review of 733 published trials on Bio-Mos®, a mannan oligosaccharide, and Actigen®, a second generation mannose rich fraction, on farm and companion animals.. Journal of Applied Animal Nutrition, Vol. 3,


    Villettaz Robichaud, M. Godden, S.M. Haines, D.M. Haley, D.B. and Pearl, D.L. 2014. Addition of gut active carbohydrates to colostrum replacer does not improve passive transfer of immunoglobulin G in Holstein dairy calves. Journal of Dairy Science, Vol. 97, Issue. 9, p. 5700.


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Effect of gut active carbohydrates on plasma IgG concentrations in piglets and calves

  • M. Lazarevic (a1), P. Spring (a2), M. Shabanovic (a3), V. Tokic (a4) and L. A. Tucker (a5)
  • DOI: http://dx.doi.org/10.1017/S1751731110000194
  • Published online: 11 February 2010
Abstract

Improving immune status in neonates is crucial to health and production. Gut active carbohydrates (GAC) have been associated with increasing immunoglobin levels and immonucompetence development in mammals. The objective of the following studies was to evaluate whether GAC (mannan-oligosaccharides) applied orally to progeny immediately following parturition, improved blood plasma immunoglobulin (Ig) type G concentrations in piglets and calves. Three trials were conducted comparing control groups with those receiving GAC orally. The first two trials used piglets that were monitored for blood IgG at 2 days of age and for changes in body weight (BW), and the third trial monitored calf IgG from birth to 21 days of age. Piglets in the experimental group received 0.75 g GAC in 10 ml saline at birth and 24 h of age. The calf trial compared the control group against calves that received 22.5 g GAC mixed into 4.5 l of colostrum (to give 5 g/l) in the first 24 h after parturition. Blood serum samples were taken at 2 days post partum in piglets, and at several time points from 6 h to 21 days of age in calves, and were analysed for IgG levels by radial immunodiffusion. In the first piglet trial, significantly higher levels (32%) of IgG were observed for piglets fed GAC (P < 0.001), and in the second, IgG concentration was elevated by 23% (P < 0.01) and BW increased by 9% (P = 0.023) with GAC supplementation. Significant improvements for calves were recorded at all time points in those fed GAC (P < 0.05), with an increase in serum IgG observed after the first day, which was maintained throughout the sampling period, resulting in a difference of 39% at the end of the trial (21 d). These findings form a basis for further studies, which are required to investigate possible modes of action involved in enhancing blood immunoglobulin concentrations in young animals, and the longer-term effects this may have on the development of the immune response.

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Corresponding author
E-mail: misha@vet.bg.ac.yu
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P Brandtzaeg 2002. Role of local immunity and breast-feeding in mucosal homeostasis and defence against infections. In Nutrition and immune function (ed. PC Calder, CJ Field and HS Gill), pp. 273320. CABI Publishing, Wallingford, UK.

G Devereux 2002. The immune system. In Nutrition and immune function (ed. PC Calder, CJ Field and HS Gill), pp. 110. CABI Publishing, Wallingford, UK.

MD Disney , PD Seeberger 2004. The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens. Chemistry and Biology 11, 17011707.

MH Fahmy 1972. Comparative study of colostrum and milk composition of seven breeds of swine. Canadian Journal of Animal Science 52, 621627.

J Fioramonti , V Theodoru , L Bueno 2003. Priobiotics: what are they? What are their effects on gut physiology? Best Practice and Research Clinical Gastroenterology 17, 711724.

ST Franklin , MC Newman , KE Newman , KI Meek 2005. Immune parameters of dry cows fed mannan oligosaccharide and subsequent transfer of immunity to calves. Journal of Dairy Science 88, 766775.

AD Gooneratne , PE Hartmann , HM Nottage 1982. The initiation of lactation in sows and the mastitis-metritis-agalactia syndrome. Animal Reproduction Science 5, 135140.

DM Hooge , MD Sims , AE Sefton , A Connolly , P Spring 2003. Effect of dietary mannan-oligosaccharide with or without bacitracin or virginiamycin on live performance of broiler chickens at relatively high stocking density on new litter. Journal of Applied Poultry Research 12, 461467.

KW Kelly 1985. Immunological consequences of changing environmental stimuli. In Animal stress (ed. GP Moberg), pp. 193224. American Physiological Society, Bethesda, MD, USA.

M Martin , MA Tesaro , N Gonzalez-Ramon , A Pineiro , F Lampreave 2005. Major plasma proteins in pig serum during post natal development. Reproduction, Fertility and Development 17, 439445.

MD Sims , KA Dawson , KE Newman , P Spring , DM Hooge 2004. Effects of dietary mannan-oligosaccharide, bacitracin methylene disalicylate or both on the live performance and intestinal microbiology of turkeys. Poultry Science 83, 11481154.

P Spring , C Wenk , KA Dawson , KE Newman 2000. The effects of dietary mannan-oligosaccharides on caecal parameters and the concentrations of enteric bacteria in the caeca of salmonella-challenged broiler chicks. Poultry Science 79, 205211.

S Zou , DG McLaren , WL Hurley 1992. Pig colostrum and milk composition: comparisons between Chinese Meishan and US breeds. Livestock Production Science 30, 115127.

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