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Is the hypodopaminergic hypothesis plausible as neural bases of ADHD?

Published online by Cambridge University Press:  07 September 2005

Adolfo G. Sadile*
Affiliation:
Department of Experimental Medicine, Second University, Naples, 80138Italy
Davide Viggiano*
Affiliation:
Department of Experimental Medicine, Second University, Naples, 80138Italy

Abstract

The “dynamic developmental theory” is based on hypofunctioning dopamine systems that follow an early overactivity phase. The theory does not consider recent experimental evidences from different attentiondeficit/ hyperactivity disorder (ADHD) models and the heterogeneity of the disorder. Alternatives are proposed that integrate available information gathered from clinical and experimental studies, with theoretical constructs.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2005

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