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Central excitation and inhibitory mechanisms and neuroplasticity are also manifested in trigeminal nociceptive pathways

Published online by Cambridge University Press:  01 September 1997

James W. Hu
Affiliation:
Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6 james.hu@utoronto.cabarry.sessle@utoronto.ca
Barry J. Sessle
Affiliation:
Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6 james.hu@utoronto.cabarry.sessle@utoronto.ca

Abstract

Central sensitization and related neurochemical mechanisms are also induced in V nociceptive pathways after craniofacial injury or inflammation. Their characteristics raise additional possibilities that may explain some of the phenomena outlined by coderre & katz, dickenson, and wiesenfeld-hallin et al. They also underscore the need for therapeutic approaches to reduce nociceptive inputs to the CNS or their neuroplastic effects which can potentially enhance post-traumatic pain.

Type
Open Peer Commentary
Copyright
© 1997 Cambridge University Press

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