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Context, connection, and coordination: The need to switch

Published online by Cambridge University Press:  03 September 2003

Robert D. Oades
Affiliation:
Clinic for Child and Adolescent Psychiatry, University of Essen, D-45147 Essen, Germany oades@uni-essen.de bernd.roepcke@uni-essen.de http://www.biopsychology.uni-essen.de
Bernd Röpcke
Affiliation:
Clinic for Child and Adolescent Psychiatry, University of Essen, D-45147 Essen, Germany oades@uni-essen.de bernd.roepcke@uni-essen.de http://www.biopsychology.uni-essen.de
Ljubov Oknina
Affiliation:
Clinic for Child and Adolescent Psychiatry, University of Essen, D-45147 Essen, Germany; Institute of Higher Nervous Activity and Neurophysiology, Moscow ljubov.oknina@uni-essen.de

Abstract

Context, connection, and coordination (CCC) describe well where the problems that apply to thought-disordered patients with schizophrenia lie. But they may be part of the experience of those with other symptom constellations. Switching is an important mechanism to allow context to be applied appropriately to changing circumstances. In some cases, NMDA-voltage modulations may be central, but gain and shift are also functions that monoaminergic systems express in CCC.

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Article Commentary
Copyright
Copyright © Cambridge University Press 2003

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