Skip to main content
×
Home
    • Aa
    • Aa

Molecular mechanisms of synaptic consolidation during sleep: BDNF function and dendritic protein synthesis

  • Clive R. Bramham (a1)
  • DOI: http://dx.doi.org/10.1017/S0140525X05230029
  • Published online: 01 February 2005
Abstract

Insights into the role of sleep in the molecular mechanisms of memory consolidation may come from studies of activity-dependent synaptic plasticity, such as long-term potentiation (LTP). This commentary posits a specific contribution of sleep to LTP stabilization, in which mRNA transported to dendrites during wakefulness is translated during sleep. Brain-derived neurotrophic factor may drive the translation of newly transported and resident mRNA.

Copyright
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Behavioral and Brain Sciences
  • ISSN: 0140-525X
  • EISSN: 1469-1825
  • URL: /core/journals/behavioral-and-brain-sciences
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×