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    Skinner, Marilyn D. and Aubin, Henri-Jean 2010. Craving's place in addiction theory: Contributions of the major models. Neuroscience & Biobehavioral Reviews, Vol. 34, Issue. 4, p. 606.


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Negative affects are parts of the addiction syndrome

  • Michel Le Moal (a1)
  • DOI: http://dx.doi.org/10.1017/S0140525X08004871
  • Published online: 01 July 2008
Abstract
Abstract

Decision-making is a complex activity for which emotions and affects are essential. Maladaptive choices depend on negative affects. Vulnerabilities to drug or non-drug objects depend on previous psychopathological comorbidities. Premorbid individual characteristics allow us to understand why some individuals – and not others – enter into the addiction cycle. Moreover, plasticity of reward neurocircuitry is, at least in past, responsible for these vulnerabilities leading to compulsive drug use.

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Behavioral and Brain Sciences
  • ISSN: 0140-525X
  • EISSN: 1469-1825
  • URL: /core/journals/behavioral-and-brain-sciences
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