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NMDA synapses can bias competition between object representations and mediate attentional selection

Published online by Cambridge University Press:  03 September 2003

Antonino Raffone ,
Jaap M. J. Murre  and
Gezinus Wolters
Antonino Raffone
Affiliation:
Department of Psychology, University of Sunderland, St. Peter's Campus, SR6 0DD Sunderland, United Kingdom antonino.raffone@sunderland.ac.uk
Jaap M. J. Murre
Affiliation:
Department of Psychology, University of Amsterdam, 1018 WB Amsterdam, and University of Maastricht, The Netherlands jaap@murre.com
Gezinus Wolters
Affiliation:
Department of Psychology, Leiden University, 2300 RB Leiden, The Netherlands wolters@fsw.leidenuniv.nl
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Abstract

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Phillips & Silverstein emphasize the gain-control properties of NMDA synapses in cognitive coordination. We endorse their view and suggest that NMDA synapses play a crucial role in biased attentional competition and (visual) working memory. Our simulations show that NMDA synapses can control the storage rate of visual objects. We discuss specific predictions of our model about cognitive effects of NMDA-antagonists and schizophrenia.

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Type
Article Commentary
Information
Behavioral and Brain Sciences , Volume 26 , Issue 1 , February 2003 , pp. 100 - 101
Copyright
Copyright © Cambridge University Press 2003

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