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Précis of O'Keefe & Nadel's The hippocampus as a cognitive map

  • John O'Keefe (a1) and Lynn Nadel (a2)
Abstract
Abstract

Theories of spatial cognition are derived from many sources. Psychologists are concerned with determining the features of the mind which, in combination with external inputs, produce our spatialized experience. A review of philosophical and other approaches has convinced us that the brain must come equipped to impose a three-dimensional Euclidean framework on experience – our analysis suggests that object re-identification may require such a framework. We identify this absolute, nonegocentric, spatial framework with a specific neural system centered in the hippocampus.

A consideration of the kinds of behaviours in which such a spatial mapping system would be important is followed by an analysis of the anatomy and physiology of this system, with special emphasis on the place-coded neurons recorded in the hippocampus of freely moving rats. A tentative physiological model for the hippocampal cognitive map is proposed. A review of lesion studies, in tasks as diverse as discrimination learning, avoidance, and extinction, shows that the cognitive map notion can adequately explain much of the data.

The model is extended to humans by the assumption that spatial maps are built in one hemisphere, semantic maps in the other. The latter provide a semantic deep structure within which discourse comprehension and production can be achieved. Evidence from the study of amnesic patients, briefly reviewed, is consistent with this extension.

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Adey W. R. (1967) Role of hippocampus in attention and learning. In: Adey W. R., and Tokizane T. (eds.), Structure and function of the limbic system: Progress in brain research, vol. 27. New York: Elsevier. [JEH]
Adey W. R., Dunlop C. W., and Hendrix C. E. (1960) Hippocampal slow waves: Distribution and phase relationships in the course of learning. Archives of Neurology, 3: 7490. [JEH]
Altman J., Brunner R. L., & Bayer S. A. (1973) The hippocampus and behavioral maturation. Behavioral Biology, 8: 557596. [AA]
Babb T. L., Carr E., and Crandall P. H. (1973) Analysis of extracellular firing patterns of deep temporal lobe structures in man. Electroencephalogra-phy and Clinical Neurophysiology-EEG Journal, 34: 247257. [JO'K]
Baddeley A. D., and Warrington E. (1970) Amnesia and the distinction between long- and short-term memory. Journal of Verbal Learning and Verbal Behavior, 9: 176189. [JO'K]
Barlow J. S. (1970) Vestibular and non-dominant parietal lobe disorders. Diseases of the Nervous System, 31: 667673. [RJD]
Barnes C. A. (1979) Memory deficits associated with senescence: A neurophy-siological and behavioral study in the rat. Journal of Comparative and Physiological Psychology, 93: 74104. [JO'K]
Barnes C. A., Nadel L., and Honig W. K. (in press) Spatial memory deficits in senescent rats. Canadian Journal of Psychology. [JO'K]
Bartlett F. C. (1932) Remembering. Cambridge: Cambridge Univ. Press. [LRS]
Becker J. T., Olton D. S., Anderson C. A., & Mayolier R. S. (1979) Both object and spatial reversal are impaired after frontal or hippocampal system damage in rats. Neuroscience Abstracts 5: 113. [RH]
Berger T. W., Alger B. E., and Thompson R. F. (1976) Neuronal substrate of classical conditioning in the hippocampus. Science, 192: 483485. [TWB, RFT]
Berger T. W., Laham R. I., and Thompson R. F. (1979) Hippocampal unit-behavior correlations during classical conditioning. Unpublished manuscript. [TWB]
Berger T. W., and Thompson R. F. (1978a) Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response: I. The hippocampus. Brain Research, 145: 323346. [TWB, JBR, RFT]
Berger T. W., and Thompson R. F. (1978b) Identification of pyramidal cells as the critical elements in hippocampal neuronal plasticity during learning. Proceedings of the National Academy of Sciences (Wash.), 75: 15721576. [TWB, RFT]
Beritoff (Beritashvili) I. S. (1965) Neural mechanisms of higher vertebrate behavior (Liberson W. T., ed. and trans.). Boston: Little, Brown. [RJD, PE, JO'K]
Beritashvili I. S. (1971) Vertebrate memory: Characteristics and origins. New York: Plenum Press. [JO'K]
Berry S. D., & Thompson R. F. (1978) Prediction of learning rate from the hippocampal EEC. Science, 200: 12981300. [RFT]
Best M. R., and Best P. J. (1976) The effects of state of consciousness and latent inhibition on hippocampal unit activity in the rat. Experimental Neurology, 51: 564573. [TWB]
Bowen F. P., Hoehn M. and Yahr M. D. (1972) Alterations in spatial orientation as determined by a route-walking test. Neuropsychologia, 10: 355361. [FBB]
Black A. H., Nadel L., and O'Keefe J. (1977) Hippocampal function in avoidance learning and punishment. Psychological Bulletin, 84: 11071129. [JAG, JWM, JO'K]
Blanchard D. C., Blanchard R. J., Lee E. M. C., & Fukunaga K. K. (1977) Movement arrest and the hippocampus. Physiological Psychology, 5: 331335. [DCB, JO'K]
Blanchard R. J., Blanchard D. C., and Fial R. A. (1970) Hippocampal lesions in rats and their effect on activity, avoidance and aggression, journal of Comparative and Physiological Psychology, 71: 92102. [JO'K]
Blanchard R. J. and Fial R. A. (1968) Effects of limbic lesions on passive avoidance and reactivity to shock. Journal of Comparative and Physiological Psychology, 66: 606612. [JO'K]
Bliss T. V. P. and Lømo T. (1970) Plasticity in a monosynaptic cortical pathway. Journal of Physiology (London), 207: 61P. [JO'K]
Blodgett H. G., McCutchan K., and Mathews R. (1949) Spatial learning in the T-maze: The influence of direction, turn, and food location. Journal of Experimental Psychology, 39: 800809. [JO'K, DSO]
Branch M. H., Olton D. S., and Best P. J. (1976). Spatial characteristics of hippocampal unit activity. Neuroscience Abstracts, 2: 368. [JO'K]
Bresnan J. (1978) A realistic transformational grammar. In: Halle M. L., Bresnan J., and Miller G. (eds.) Linguistic theory and psychological reality, pp. 159. Cambridge: M.I.T. Press. [RJ]
Butters N., and Cermak L. S. (1974) Some comments on Warrington and Baddeley's report of normal short-term memory in amnesic patients. Neuropsychologia, 12: 283285. [JO'K]
Butters N., and Cermak L. S. (1975) Some analyses of amnesic syndromes in brain-damaged patients. In: Isaacson R. L. and Pribram K. H. (eds.), The hippocampus, vol. 2. New York: Plenum Press. [RPK]
Butters N., Soeldner C., and Fedio P. (1972) Comparison of parietal and frontal lobe spatial deficits in man: Extrapersonal vs personal (egocentric) space. Perceptual and Motor Skills, 34: 2734. [RPK]
Caul W. F., Jarrard L. E., Miller R. E., & Korn J. H. (1969) Effects of hippocampal lesions on heart rate in aversive conditioning. Physiology and Behavior, 4: 917922. [RH]
Chomsky N. (1957). Syntactic structures. The Hague: Mouton. [JO'K]
Chomsky N. (1965). Aspects of the theory of syntax. Cambridge, Mass.: M.I.T. Press. [O'K, RJ]
Chomsky N. (1972) Studies on semantics in generative grammar. The Hague: Mouton. [RJ]
Clark C. V. H., & Isaacson R. L. (1965) Effect of bilateral hippocampal ablation on DRL performance. Journal of Comparative & Physiological Psychology, 59: 137140. [PE]
Correll R. E., and Scoville W. B. (1965) Performance on delayed match following lesions of medial temporal lobe structures. Journal of Comparative and Physiological Psychology, 80: 360367. [JAH]
Corsi P. M. (1972) Human memory and the medial temporal region of the brain. Unpublished doctoral thesis. McGill Univ. Dept. of Psychology. [LRS]
Critchley M. (1953) The parietal lobes. New York: Hafner. [RPK]
Crowne D. P., Konow A., Drake K. J., and Pribram K. H. (1972) Hippocampal electrical activity in the monkey during delayed alternation problems. EEG and Clinical Neurophysiology, 33: 567578. [JEH]
Dashiell J. F. (1930) Direction orientation in maze running by the white rat. Comparative Psychology Mongraphs., 7: 172. [JO'K]
Deadwyler S. A., West M., and Lynch G. (1979) Activity of dentate granule cells during learning: Differentiation of perforant path input. Brain Research, 169: 2943. [JBR]
Dean P. (1974) The effect of inferotemporal lesions on memory for visual stimuli in rhesus monkeys. Brain Research, 77: 451469. [JAH]
Dick A. O. (1976) Spatial abilities. In: Whitaker M. and Whitaker H. A. (eds.), Studies in neurolinguistics, vol. 2. New York: Academic Press. [RPK]
Disterhoft J. F., Kwan H. H., & Lo W. D. (1977) Nictitating membrane conditioning to tone in the immobilized albino rabbit. Brain Research, 137: 127143. [RFT]
Douglas R. J. (1966a) Cues for spontaneous alternation. Journal of Comparative and Physiological Psychology, 62: 171183. [RJD, JO'K]
Douglas R. J. (1966b) Spontaneous alternation and middle ear disease. Psychonomic Science, 4: 243244. [RJD]
Douglas R. J. (1967) The hippocampus and behavior. Psychological Bulletin, 67: 416442. [RJD]
Douglas R. J. (1972) Pavlovian conditioning and the brain. In: Boakes R. and Halliday M. (eds.), Inhibition and learning, pp. 529553. London: Academic Press. [AA, RJD]
Douglas R. J. (1975) The development of hippocampal function: Implications for theory and for therapy. In: Isaacson R. and Pribram K. (eds. ), The hippocampus, II. pp. 327361. New York: Plenum Press. [RJD]
Douglas R. J., Mitchell D., and Del Valle R. (1974) Angle between choice alleys as a critical factor in spontaneous alternation. Animal Learning and Behavior, 2: 218220. [RJD]
Douglas R. J., and Pribram K. H. (1966) Learning and limbic lesions. Neuropsychologia, 4: 197220. [RH.RPK]
Downs R. M., and Stea D. (1977) Maps in minds: Reflections on cognitive mapping. New York: Harper and Row. [JO'K]
Ellen P., & Aitken W. G. Jr (1970) Absence of overresponding on a DRL schedule by hippocampally-lesioned rats. Physiology & Behavior, 5: 489495. [PE]
Ellen P., Aitken W. G. jr & Walker R. (1973) Pretraining effects on performance of rats with hippocampal lesions. Journal of Comparative & Physiological Psychology, 81, 622628. [PE]
Ellen P., Wilson A. S., & Bruell E. W. (1964) Septal inhibition and training behavior in the rat. Experimental Neurology, 10: 120132. [PE]
Evarts E. V. (1964) Temporal patterns of discharge of pyramidal tract neurons during sleep and waking in the monkey. Journal of Neurophysiology, 27: 152171. [RFT]
Fillmore C. J. (1968). The case for case. In Bach E. E., and Harms R. T. (eds.), Universals in linguistic theory, pp. 188. New York: Holt, Rinehart and Winston. [JO'K]
Fillmore C. J. (1971). Types of lexical information. In Steinberg D. D. and Jakobovits L. A. (eds.), Semantics, pp. 370392. Cambridge: Cambridge Univ. Press. [JO'K]
Finke R. A., & Kosslyn S. M. (in press) Mental imagery acuity in the peripheral visual field. Journal of Experimental Psychology: Human Perception and Performance. [SP]
Finke R. A. & Schmidt M. J. (1977) Orientation-specific color aftereffects following imagination. Journal of Experimental Psychology: Human Perception and Performance, 3: 599606. [SP]
Fodor J. (1975) The language of thought. New York: Crowell. [RJ]
Gaffan D. (1977) Monkey's recognition memory for complex pictures and the effect of fornix transection. Quarterly Journal of Experimental Psychology, 29: 505514. [HU]
Gibson J. J. (1950). The perception of the visual world. Boston: Houghton Mifflin. [JO'K]
Gibson J. J. (1966). The senses considered as perceptual systems. Boston: Houghton Mifflin. [JO'K]
Glazer H. I. (1974) Instrumental conditioning of hippocampal theta and subsequent response persistence. Journal of Comparative and Physiological Psychology, 86: 267273. [AA]
Gleitman H. (1955) Place learning without prior performance. Journal of Comparative and Physiological Psychology, 48: 7779. [PE, JO'K]
Gormezano I., Schneiderman N., Deaux E., & Fuentes I. (1962) Nictitating membrane: Classical conditioning and extinction in the albino rabbit. Science, 138: 3334. [RFT]
Grastyan E., Lissak K., Madarasz I., and Donhoffer H. (1959) Hippocampal electrical activity during the development of conditioned reflexes. EEG and Clinical Neurophysiology, 11: 409430. [JEH]
Gray J. A. (1970) Sodium amobarbital, the hippocampal theta rhythm, and the partial reinforcement extinction effect. Psychological Review, 77: 465480. [JO'K]
Gray J. A. (1977) Drug effects of fear and frustration: Possible limbic site of action of minor tranquilizers. In: Iversen L. L., Iversen S. D., & Snyder S. H. (eds.), Handbook of psychopharmacology: 8. Drugs, neurotransmitters & behavior. New York & London: Plenum Press. [AA]
Gray J. A., Feldon J., Rawlins J. N. P., Owen S., and McNaughton N. (1978) The role of the septo-hippocampal system and its noradrenergic afferents in behavioural responses to nonreward. In: Elliott K., and Whelan J. (eds.), Functions of the septo-hippocampal system, Ciha Foundation Symposium No. 58 (n.s.), pp. 275300. Amsterdam: Elsevier. [JAG]
Green J. D. and Arduini A. (1954) Hippocampal electrical activity in arousal. Journal of Neurophysiology, 17: 533557. [JEH]
Harper R. M. (1971) Frequency changes in hippocampal electrical activity during movement and tonic immobility. Physiology and Behavior, 7: 5558. [JEH]
Hebb D. O. (1968) Concerning imagery. Psychological Review, 75: 466477. ESP]
Henke P. G. (1974) Persistence of runway performance after septal lesions in rats. Journal of Comparative and Physiological Psychology, 86: 760767. [AA]
Herrnstein R. J., and Boring E. G., eds. (1966). A source book in the history of psychology. Cambridge, Mass.: Harvard Univ. Press. [JO'K]
Hill A. J. (1976). Neuronal activity in hippocampus during a spatial alternation task. Neuroscience Abstracts, 2: 388. [JO'K]
Hirsh R. (1974) The hippocampus and contextual retrieval of information from memory. A theory. Behavioral Biology, 12: 421444. [RFT]
Hoehler F. K., & Thompson R. F. (1980) The effect of temporal single-alternation on learned increases in hippocampal unit activity in classical conditioning of the rabbit nictitating membrane response. Physiological Psychology, in press. [RFT]
Holmes J. E., and Adey W. R. (1960) Electrical activity of the entorhinal cortex during conditioned behavior. American Journal of Physiology, 199: 741744. [JEH]
Horel J. A. (1978) The neuroanatomy of amnesia: A critique of the hippocampal memory hypothesis. Brain, 101: 403445. [JAH, JO'K, LRS]
Hubel D., and Wiesel T. (1962) Receptive fields, binocular interaction, and functional architecture in the cat's visual cortex. Journal of Physiology, 160: 106154. [JAG]
Hull C. L. (1932) The goal gradient hypothesis and maze learning. Psychological Review, 39: 2543. [JO'K]
Hull C. L. (1934) The concept of the habit-family hierarchy and maze learning, I. Psychological Review, 41: 3354. [JO'K]
Hutt S. J., and Hutt C. (1970) Direct observation and measurement of behavior. Springfield, Ill.: Thomas.
Hyvarinen J., and Poranen A. (1974) Function of the parietal associative area 7 as revealed from cellular discharges in alert monkeys. Brain, 97: 673692. [HH]
Inglis J. (1970) Shock, surgery and cerebral asymmetry. British Journal of Psychiatry, 117: 143148. [LRS]
Isseroff A. (1979) Limited recovery of spontaneous alternation after extensive hippocampal damage: Evidence for a memory impairment. Experimental Neurology, 64: 284294. [JO'K]
Jabbur S. J. and Towe A. L. (1961) Cortical excitation of neurons in dorsal column nuclei of cat, including an analysis of the pathways. Journal of Neurophysiology, 24: 499509. [JO'K]
Jacobson C. F., and Nissen H. W. (1937) Studies of cerebral function in primates: IV. The effect of frontal pole lesions on the delayed alternation habit in monkeys. Journal of Comparative Psychology, 23: 101112. [GJT]
Jackendoff R. (1972) Semantic interpretation in generative grammar. Cambridge: M.I.T. Press. [RJ]
Jackendoff R. (1976) Toward an explanatory semantic representation. Linguistic Inquiry, 7: 89150. [RJ, JO'K]
Jackendoff R. (1978) Grammar as evidence for conceptual structure. In: Halle M., Bresnan J., and Miller G. (eds.) Linguistic theory and psychological reality, pp. 201228. Cambridge: M.I.T. Press. [RJ]
(in preparation) Semantics and Cognition. [RJ]
Jarrard L. E. (1975) The role of interference in retention by rats with hippocampal lesions. Journal of Comparative and Physiological Psychology, 89: 400408. [LEJ, HU]
Jarrard L. E. (1976) Anatomical and behavioral analysis of hippocampal cell fields. Journal of Comparative and Physiological Psychology, 90: 10351050. [LEJ]
Jarrard L. E. (1978a) Selective hippocampal lesions: Differential effects on performance by rats of a spatial task with preoperative versus postoperative training. Journal of Comparative and Physiological Psychology, 92: 11191127. [LEJ]
Jarrard L. E. (1978b) Selective hippocampal lesions and spatial discrimination in the rat. Society for Neuroscience Abstracts, 3: 222. [LEJ]
Jarrard L. E. & Becker J. T. (1977) The effects of selective hippocampal lesions on DRL behavior in rats. Behavioral Biology, 21: 393404. [LEJ]
Jarrard L. E., and Isaacson R. L. (1965). Hippocampal ablation in rats: Effects of intertriai interval. Nature (London) 207: 109110. [JO'K]
Jones-Gotman M., & Milner B. (1978) Right temporal-lobe contribution of image-mediated verbal learning. Neuropsychologia, 16: 6171.
Kaada B. R., Rasmussen E. W., and Kveim O. (1961) Effects of hippocampal lesions on maze learning and retention in rats. Experimental Neurology, 3: 333355. [HU]
Kandel E. R. (1976) The cellular basis of behavior. San Francisco: Freeman press. [RFT]
Kesner R. P. (1980) An attribute analysis of memory: The role of the hippocampus. Physiological Psychology, in press. [RPK]
Kilmer W. L., and McLardy T. (1970) A model of hippocampal CA3 circuitry. International Journal of Neuroscience, 1: 107112. [JO'K]
Kilmer W. L., and McLardy T. (1971) A diffusely preprogrammed but sharply trainable hippocampus model. International Journal of Neuroscience, 2: 241248. [JO'K]
Kimble D. P. Hippocampus and internal inhibition. (1968) Psychological Bulletin, 70: 285295. [RJD]
Kimble D. P. (1969) Possible inhibitory functions of the hippocampus. Neuropsychologia, 7: 235244. [AA]
Kimble D. P. (1975) Choice behavior in rats with hippocampal lesions. In: Isaacson R. L., and Pribram K. H. (eds.), The hippocampus, vol. 2. New York: Plenum Press. [JO'K]
Klüver H., and Bucy P. C. (1939) Preliminary analysis of functions of the temporal lobes in monkeys. Archives of Neurology and Psychiatry, 5: 3354. [JAH]
Køhler C. (1976a) Habituation of the orienting response after medial and lateral septal lesions in the albino rat. Behavioral Biology, 16: 6372. [HU]
Køhler C. (1976b) Habituation after dorsal hippocampal lesions: A test dependent phenomenon. Behavioral Biology, 18: 89110. [HU]
Kosslyn S. M., Ball T. M., & Reiser B. J. (1978) Visual images preserve metric spatial information. Journal of Experimental Psychology: Human Perception and Performance, 4: 4760. [SP]
Kosslyn S. M., Pinker S., Smith G., & Shwartz S. P. (1979) On the demystification of mental imagery. The Behavioral and Brain Sciences. 2: 535581. [JO'K, SP]
Lakoff G. (1971) On generative semantics. In: Steinberg D., and Jakobovits L. (eds.) Semantics: An interdisciplinary reader, pp. 232296. Cambridge: Cambridge Univ. Press. [RJ]
Landfield P. W. (1976) Function of synchronous EEG rhythms. In: Gispen W. H. (ed.), Molecular and functional neurobiology. New York: Elsevier. [JEH]
Linton M. (1975) Memory for real-world events. In: Norman D. A., Rumelhart D. E., and the LNR Research Group, Exploration in cognition. San Francisco: Freeman.
Livesey P. J. (1975) Fractionation of hippocampal function in learning. In: Isaacson R. L., and Pribram K. H., (eds.), The hippocampus: 2. Neurophysiology and behavior, pp. 279301. New York: Plenum Press. [HU]
Lotze H. (1886). Outlines of psychology: Dictated portions of the lectures of Hermann Lotze (trans Ladd G. T.). Boston: Ginn. [JO'K]
Mach E. (1897). Contributions to the analysis of the sensations (trans. Williams C. M.). Chicago, Ill.: Open Court. [JO'K]
McKellar P. The investigation of mental images. (1965) In: Baret S. A., and McLaren A. (eds. ), Penguin Science Survey B (Biological Sciences). New York: Penguin Books. [SP]
McLardy T. (1960) Neurosyncytial aspects of the hippocampal mossy fibre system. Confina Neurologica, 20: 117. [JO'K]
McNamara H. J., Long J. B., and Wike E. L. (1956) Learning without response under two conditions of external cues. Journal of Comparative and Physiological Psychology, 49: 477480. [DE, JO'K]
Mahut H. (1971) Spatial and object reversal learning in monkeys with partial temporal lobe ablations. Neruopsychologia, 9: 409424. [JAH]
Mahut H., and Cordeau J. (1963) Spatial reversal deficit in monkeys with amygdalohippocampal ablations. Experimental Neurology, 7: 426434. [JAH]
Marr D. (1971) Simple memory: A theory for archicortex. Philosophical Transactions of the Royal Society (London) [Biological Science], 262: 2381. [O'K, TVPB]
Marr D., & Nishihara H. K. (1978) Visual information processing: Artificial intelligence and the sensorium of sight. Technology Review, 81: 123. [SP]
Marslen-Wilson W. D., and Teuber H.-L. (1975) Memory for remote events in anterograde amnesia: Recognition of public figures from newsphoto-graphs. Neuropsychologia, 13: 353364. [JO'K, LRS]
Menzel E. W. Cognitive mapping in chimpanzees. (1978) In: Hulse S. H., Fowler H., and Honig W. K. (eds.), Cognitive processes in animal behavior. Hillsdale, N.J.: Erlbaum. [JO'K, GJT]
Mesulam M., Van Hoesen G. W., Pandya D. N., and Geschwind N. (1977) Limbic and sensory connections of the inferior parietal lobule (area PG) in the rhesus monkey: A study with a new method for horseradish peroxy-dase. Brain Research 136: 393414. [HH]
Miller G., and Johnson-Laird P. (1976) Language and perception. Cambridge, Mass.: Harvard Univ. Press. [RJ, JO'K]
Milner B. (1965) Visually-guided maze learning in man: Effects of bilateral hippocampal, bilateral, frontal, and unilateral cerebral lesions. Neuropsy-chologia, 3: 317338. [HH, JO'K, LRS]
Milner B. (1968a) Preface: Material specific and generalized memory loss. Neuropsychologia, 6: 175179. [RPK, JO'K]
Milner B. (1968b) Visual recognition and recall after right temporal-lobe excision in man. Neuropsychologia, 6: 191209. [LRS]
Milner B. (1972) Disorders of learning and memory after temporal lobe lesions in man. Clinical Neurosurgery, 19: 421446. [LRS]
Mishkin M. (1954) Visual discrimination performance following partial ablations of the temporal lobe: II. Ventral surface vs. hippocampus. Journal of Comparative and Physiological Psychology, 147: 187193. [JAH]
Milner B. (1978) Memory in monkeys severely impaired by combined but not by separate removal of amygdala and hippocampus. Nature, 273: 297298. [HU, LRS]
Mishkin M., and Oubre J. L. (1976) Dissociation of deficits on visual memory tasks after inferior temporal and amygdala lesions in monkeys. Neuroscience Abstracts, II, pt. 2: p. 1127. [JAH]
Mitchell S., and Ranck J. B. Jr (1977) Firing patterns and behavioral correlates of neurons in entorhinal cortex of freely moving rats. Neuroscience Abstracts 3: 202. [JO'K]
Moore J. W. (1980) Information processing in space time by the hippocampus. Physiological Psychology, in press. [JO'K, RFT]
Morris R. G. M., Black A. H., and O'Keefe J. (1976). Hippocampal EEG during a ballistic movement (abstract). Neuroscience Letters, 39: 102. [JO'K]
Mountcastle V. B. (1976) The world around us: Neural command functions for selective attention. Neurosciences Research Program Bulletin, 14, suppl.: 147. [HH]
Mountcastle V. B. (1978) Some neural mechanisms for directed attention. In: Buser P. A., and Rougeul-Buser A. (eds.), Cerebral correlates of conscious experience, IN-SERM Symposium. Amsterdam: North Holland Publishing Company. [HH]
Mountcastle V. B., Lynch J. C., Georgopoulos A., Sakata H., and Acuna C. (1975) Posterior parietal association cortex of the monkey: Command functions for operations within extrapersonal space. Journal of Neuro-physiology, 38: 871908. [HH]
Myhrer T. (1975) Locomotor, avoidance, and maze behavior in rats with selective disruption of hippocampal output. Journal of Comparative and Physiological Psychology, 89: 759777. [LEJ]
Nadel L. (1977) Amnesia and cognitive mapping in humans. Paper presented at the Society for Neuroscience Seventh Annual Meeting, Anaheim, Calif. [AJN]
Nadel L. (1979a) Cognitive maps: At the choice point again. Paper presented at the American Psychological Association Meetings, New York. [JO'K]
Nadel L. (1979b) Working memory won't work. Behavioral and Brain Sciences, Vol. 2, No. 4. [LN, JO'K, DSO]
Nadel L. (in press) Cognitive and neural maps. In: Juscyzk P. W., and Klein R. (eds.), Essays on the nature of thought: A symposium in honor of D. O. Hebb. Hillsdale, N.J.: Erlbaum. JO'K]
Nadel L., and O'Keefe J. (1974) The hippocampus in pieces and patches: An essay on modes of explanation in physiological psychology. In: Bellairs R. and Gray E. G. (eds.), Essays on the nervous system. A Festschrift for Prof. J. Z. Young. Oxford: Clarendon Press. [LN, JO'K]
Nadel L., O'Keefe J., and Black A. H. (1975) Slam on the brakes: A critique of Altman, Brunner and Bayer's response inhibition model of hippocampal function. Behavioral Biology, 14: 151162. [LNJO'K]
Nadel L., and Willner J. (in press) Context and conditioning: A place for space. Physiological Psychology. [JO'K]
Nonneman A. J., and Isaacson R. L. (1973). Task dependent recovery after early brain damage. Behavioral Biology, 8: 143172. [JO'K]
Norman D. A., and Rumelhart D. E. (1975) Explorations in cognition. San Francisco: Freeman. [LRS]
O'Keefe J. (1976) Place units in the hippocampus of the freely moving rat. Experimental Neurology, 51: 78109. [TWBJO'K]
O'Keefe J. (1979a) Hippocampal function: Does the working memory hypothesis work? Should we retire the cognitive map theory? Behavioral and Brain Sciences, Vol. 2, No. 4. [LN]
O'Keefe J. (1979b) A review of the hippocampal place cells. Progress in Neurobiology 13: 419–34. [JO'K]
O'Keefe J., and Black A. H. (1978) Single unit and lesion experiments on the sensory inputs to the hippocampal cognitive map. In Functions of the septo-hippocampal system, pp. 179192. Ciba Foundation Symposium 58. New York: Elsevier. [JAG]
O'Keefe J., and Dostrovsky J. (1971) The hippocampus as a spatial map: Preliminary evidence from unit activity in the freely-moving rat. Brain Research, 34: 171175. [JAG]
O'Keefe J., Nadel L., Keightley S., and Kill D. (1975) Fornix lesions selectively abolish place learning in the rat. Experimental Neurology 48: 152–66. [JAG]
O'Keefe J., and Nadel L. (1974) Maps in the brain. New Scientist, 62: 749751. [RFT]
O'Keefe J., and Nadel L. (1978) The hippocampus as a cognitive map. Oxford: Clarendon Press. [JO'K, RET et al]
O'Keefe J., Nadel L., and Willner J. (1979) Turning out irrelevancy? Comments on Solomon's temporal mapping view of hippocampus. Psychological Bulletin. 86: 1280–9 [JO'K]
Olds J. (1965) Opérant conditioning of single unit responses. Proceedings of the 23rd Congress of Physiological Sciences. Excerpta Medica International Congress Series., no. 87: 372380. [JO'K]
Olds J. (1972) Learning and the hippocampus. Revue Canadienne de Psychologie, 31: 215238. [AA]
Olds J., Disterhoft J. F., Segal M., Kornblith C. L. and Hirsh R. (1972) Learning centers of rat brain mapped by measuring latencies of conditioned unit responses. Journal of Neurophysiology, 35: 202219. [TWB, RFT]
Olton D. S. (1969) Fear, hippocampal lesions and avoidance behaviour. Communications in Behavioral Biology A 3: 259262. [JO'K]
Olton D. S. (1978) Characteristics of spatial memory. In: Hülse S. H., Honig W. K., and Fowler H. (eds.), Cognitive processes in animal behavior, pp. 341373. Hillsdale, N.J.: Erlbaum. [DSO]
Olton D. S. (1979) Mazes, maps, and memory. American Psychologist, 34: 583596. [DSO]
Olton D. S., Becker J. T., and Handelmann G. E. (1979) Hippocampus, space, and memory. Behavioral and Brain Sciences, Vol. 2, No. 4. [RJD, JAG, AJN, JO'K, DSO, HU]
Olton D. S., and Isaacson R. L. (1968) Hippocampal lesions and active avoidance. Physiology and Behavior, 3: 719724. [JO'K]
Olton D. S., and Papas B. C. (in press) Spatial memory and hippocampal function. Neuropsychologia. [LEJ]
Olton D. S., and Samuelson R. J. (1976) Remembrance of places passed: Spatial memory in rats. Journal of Experimental Psychology – Animal Behavior Processes, 2: 97116. [DSO]
Orbach J., Milner M., and Rasmussen T. (1960) Learning and retention in monkeys after amygdala-hippocampus resection. Archives of Neurology, 3: 230251. [JAH]
Osborne B., and Black A. H. (1978) A detailed analysis of behavior during the transition from acquisition to extinction in rats with fornix lesions. Behavioral Biology, 23: 271290. [JO'K]
Pearlman C. A. (1979) REM sleep and information processing: Evidence from animal studies. Neuroscience and Biobehavioral Reviews, 3: 5768. [JEH]
Penfield W. (1958) The excitable cortex in conscious man. Liverpool: Liverpool Univ. Press. [JO'K]
Penfield W., and Mathieson G. (1974) Memory: Autopsy findings and comments on the role of hippocampus in experiential recall. Archives of Neurology, 31: 145154. [JEH]
Perkel D. H., and Bullock T. H. (1968) Neural coding. Neurosciences Research Program Bulletin, 6. [TWB]
Pinker S. (1979) The representation of three-dimensional space in mental images. Unpublished doctoral dissertation, Harvard University. [SP]
Pinker S. and Finke R. A. (in press) Emergent two-dimensional patterns in images rotated in depth. Journal of Experimental Psychology: Human Perception and Performance. [SP]
Pinker S. and Kosslyn S. M. (1978) The representation and manipulation of three-dimensional space in mental images. Journal of Mental Imagery, 2: 6984. [SP]
Pinker S. and Kosslyn S. M. (in press) Mental imagery and the third dimension. Journal of Experimental Psychology: General. [SP]
Pohl W. (1973) Dissociation of spatial discrimination deficits following frontal and parietal lesions in monkeys. Journal of Comparative and Physiological Psychology, 82: 227239. [RPK]
Poincaré H. (1913) The foundations of science (trans. Halsted G. B.). Lancaster, Pa.: Science Press. [JO'K]
Pond F. J., and Schwartzbaum J. S. (1972) Interrelationships of hippocampal EEG and visual evoked responses during appetitive behavior in rats. Brain Research, 43: 119137. [CHV]
Ranck J. B. Jr (1973) Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats: I. Behavioral correlates and firing repertoires. Experimental Neurology, 41: 461531. [TWB, JEH, JO'K, RFT]
Ranck J. B. Jr (1975) Behavioral correlates and firing repertoires of neurons in the dorsal hippocampal formation and septum of unrestrained rats. In: Isaacson R. L., & Pribram K. H. (eds.), The hippocampus, II. New York: Plenum Press. [JO'K, RFT]
Ranck J. B. Jr (1978) Hippocampal units and theta activity (General Discussion II). In Ciba Foundation Symposium 58 (new series), Functions of the septo-hippo-campal system, pp. 309319. Amsterdam: Elsevier /Excerpta Medica/ North-Holland. [RFT]
Rawlins J. N. P. (1979) Advancing memorial theories of hippocampal function. Behavioral and Brain Sciences, Vol. 2, No. 4. [JAG]
Rawlins J. N. P., Feldon J., and Gray J. A. (in press) The effects of hippocam-pectomy and of fimbria section upon the partial reinforcement extinction effect in rats. Experimental Brain Besearch. [JAG, JO'K]
Restie R. (1957) Discrimination of cues in mazes: A resolution of the “place-vs.-response” question. Psychological Review, 64: 217228. [DSO]
Robinson D. L., and Goldberg M. E. (1978) Sensory and behavioral properties of neurons in posterior parietal cortex of the awake, trained monkeys. Federation Proceedings, 37: 22582261. [HH]
Robinson D. L., Goldberg M. E., and Stanton G. B. (1978) Parietal association cortex in the primate: Sensory mechanisms and behavioral modulations. Journal of Neurophysiology, 41: 910932. [HH]
Roesen D. L., and Van Hoesen G. W. (1977) Hippocampal efferente reach widespread areas of cerebral cortex and amygdala in the Rhesus monkey. Science, 198: 315317. [HH]
Schmaltz L. W., and Isaacson R. L. (1966a) The effect of preliminary training conditions upon DRL performance in the hippocampectomized rat. Physiology & Behavior, 1: 175182. [PE]
Schmaltz L. W., and Isaacson R. L. (1966b) Retention of a DRL 20 schedule by hippocampectomized and partially neodecorticate rats. Journal of Comparative & Physiological Psychology, 62: 128132. [PE]
Schmaltz L. W., and Isaacson R. L. (1968) The effect of blindness on DRL 20 performance exhibited by animals with hippocampal destruction. Psychonomic Science, 11: 241242. [PE]
Schmaltz L. W., and Theios J. (1972) Acquisition and extinction of a classically conditioned response in hippocampectomized rabbits (Oryctolagus cunniculus). Journal of Comparative & Physiological Psychology, 79: 328333. [RFT]
Segal M. (1973) Flow of conditioned responses in limbic telencephalic system of the rat. Journal of Neurophysiology, 36: 840854. [TWB, JBR, RFT]
Semmes J., Weinstein S., Ghent L., and Teuber H.-L. (1955) Spatial orientation in man after cerebral injury: I. Analysis by locus of lesions. Journal of Psychology, 39: 227244. [RJD, JO'K]
Semmes J., Weinstein S., Ghent L., and Teuber H.-L. (1963) Correlates of impaired orientation in personal and extrapersonal space. Brain, 86: 747772. [RJD, JO'K, RFT]
Shepard R. N. (1978) The mental image. American Psychologist, 33: 125137. [SP]
Shepard R. N., and Metzler J. (1971) Mental rotation of three-dimensional objects. Science, 171: 701703. [SP]
Silveira J. M., and Kimble D. P. (1968) Brightness discrimination and reversal in hippocampally lesioned rat. Physiology and Behavior, 3: 625630. [RH]
Solomon P. R. (1977) Role of the hippocampus in blocking and conditioned inhibition of the rabbit's nictitating membrane response. Journal of Comparative & Physiological Psychology, 91: 407417. [RFT]
Solomon P. R. (1980) Temporal versus spatial information processing theories of hippocampal function. Psychological Bulletin, in press. [JWM, RFT]
Solomon P. R., and Moore J. W. (1975) Latent inhibition and stimulus generalization of the classically conditioned nictitating membrane response in rabbits (Oryctolagus cunniculus) following dorsal hippocampal ablations. Journal of Comparative & Physiological Psychology, 89: 11921203. [RFT]
Squire L. R. (1980) The neuropsychology of amnesia: An approach to the study of memory and aging. In: Fozard J., and Poon L. (eds.), Memory and aging. Hillsdale, N.J.: Erlbaum. [LRS]
Squire L. R., and Cohen N. (1979) Memory and amnesia: Resistance to disruption develops for years after learning. Behavioral and Neural Biology, 25: 115215. [LRS]
Squire L. R., and Moore R. Y. (1979) Dorsal thalamic lesion in a noted case of chronic memory dysfunction. Annals of Neurology, in press. [LRS]
Squire L. R., & Schlapfer W. T. (1980) Biochemical aspects of learning, memory and its disorders. In: Praag H. M. van, Lader M. H., Rafaelsen O. J., & Sachar E. J. (eds.), Handbook of biological psychiatry: II. Brain mechanisms and abnormal behavior. New York: Marcel Dekker, [LRS]
Squire L. R., & Slater P. C. (1978a) Bilateral and unilateral ECT: Effects on verbal and nonverbal memory. American Journal of Psychiatry, 11: 13161320. [LRS]
Squire L. R., & Slater P. C. (1978b) Anterograde and retrograde memory impairment in chronic amnesia. Neuropsychologia, 16: 313322. [LRS]
Squire L. R., Slater P. C., & Chace P. M. (1975) Retrograde amnesia: Temporal gradient in very long-term memory following electroconvulsive therapy. Science, 187: 7779. [LRS]
Squire L. R., Slater P. C., & Miller P. (1980) Retrograde amnesia following ECT: Long-term follow-up studies. Archives of General Psychiatry, in press. [LRS]
Sundberg H., and Køhler C. (1979) Orienting and habituation after lesions of the medial entorhinal cortex in the albino rat. University of Bergen, in preparation. [HU]
Stein D. G., Rose J. J., Graziadei J., Mishkin D., & Brink J. (1969) Central nervous system: recovery of function. Science, 166: 528530. [JO'K]
Suzuki A., Augerinos G., and Black A. H. (in press) Stimulus control of spatial behavior on the eight arm maze in rats. Learning and motivation.
Talland G. (1965) Deranged memory. New York: Academic Press. [JO'K, LRS]
Tolman E. C. (1932). Purposive behaviour in animals and men. New York: Century. [JO'K]
Tolman E. C. (1948) Cognitive maps in rats and men. Psychological Review, 55: 189208. [PE, JO'K]
Teitelbaum H. (1964) A comparison of the effects of orbito-frontal and hippocampal lesions upon discrimination learning and reversal in the cat. Experimental Neurology, 9: 284289. [RH]
Thomas G. J. (1978) Delayed alternation in rats after pre- or post-commissural fornicotomy. Journal of Comparative and Physiological Psychology, 92: 11281136. [GJT]
Thomas G. J., & Brito G. N. O. (in preparation) Medial prefrontal cortex, sep-to-hippocampal circuitry and T-maze alternation in rats. [GJT]
Thompson R. F., & Berger T. W. (1979) Responses of single hippocampal neurons during classical conditioning. Neuroscience Abstracts, 5: 722. [RFT]
Thompson R. F., Berger T. W., Cegavske C. F., Patterson M. M., Roemer R. A., Teyler T. J., & Young R. A. (1976) The search for the engram. American Psychologist, 31: 209227. [RFT]
Thompson R. F., & Glanzman D. G. (1976) Neural and behavioral mechanisms of habituation and sensitization. In: Leaton R. N., & Tighe T. J. (eds.), Habituation: Perspectives from child development, animal behavior, and neurophysiology. Hillsdale, N.J.: Erlbaum. [RFT]
Towe A. L. (1973) Motor cortex and the pyramidal system. In: Maser J. D. (ed.), Efferent organization and the integration of behavior. New York: Academic Press. [RFT]
Tulving E. (1972) Episodic and semantic memory. In: Tulving E., and Donaldson W. (eds.), Organization of memory, New York: Academic Press. [RPK]
Ungher J., & Sirian S. (1971) Vestibular short-term memory deficits due to behavior disturbances induced by fornix lesions in cat. Review of Roumanian Neurology, 8: 407417. [PE]
Ursin H., Dalland T., Ellertsen B., Herrmann T., Johnsen T. B., Livesey P., Zaidi Z., and Wahl H. (1978) Multivariate analysis of the septal syndrome. Ciba Foundation, Symposium on Functions of the septo-hippo-campal system. London [HU]
Ursin R., Ursin H., and Olds J. (1966) Self-stimulation of hippocampus in rats. Journal of Comparative and Physiological Psychology, 61: 353359. [HU]
Vanderwolf C. H. (1969) Hippocampal electrical activity and voluntary movement in the rat. Electroencephalography and Clinical Neurophysiology, 26: 407418. [JO'K]
Vanderwolf C. H. (1971) Limbic-diencephalic mechanisms of voluntary movement. Psychological Review, 78: 83113. [JO'K]
Vanderwolf C. H. (1975) Neocortical and hippocampal activation in relation to behaviour: Effects of atropine, eserine, phenothiazines and amphetamine. Journal of Comparative and Physiological Psychology, 88: 300323. [JO'K]
Vanderwolf C. H., Bland B. H., and Whishaw I. Q. (1973) Diencephalic hippocampal and neocortical mechanisms in voluntary movement. In: Maser J. D., (ed.), Efferent organization and the integration of behaviour, pp. 229262. New York: Academic Press. [JO'K]
Vanderwolf C. H., and Heron W. (1964) Electrocephalographic waves with voluntary movement: Study in the rat. Archives of Neurology, 11: 379384. [JEH]
Vanderwolf C. H., Kramis R., & Robinson T. E. (1978) Hippocampal electrical activity during waking behavior and sleep: Analyses using centrally acting drugs. In: Elliott K., and Whelan J. (eds.), Functions of the septo-hippocampal system. Ciba Foundation Symposium No. 58, pp. 199221. Amsterdam: Elsevier. [CHV]
Vinogradova O. S. (1970) Registration of information and the limbic system. In: Horn G., and Hinde R. A. (eds.), Short-term changes in neural activity and behaviour, pp. 95140. Cambridge: Cambridge Univ. Press. [JO'K]
Vinogradova O. S. (1975) Functional organization of the limbic system in the process of registration of information: Facts and hypotheses. In: Isaacson R. L., & Pribram K. H. (eds.), The hippocampus, vol. II. New York: Plenum Press. [JO'K, RFT]
Vinogradova O. S., and Brazhnik E. S. (1978) Neuronal aspects of septo-hip-pocampal relations. In: Elliott K., and Whelan J. (eds.), Functions of the septo-hippocampal system. Ciba Foundation Symposium No. 58 (n.s), pp. 145177. Amsterdam: Elsevier. [JAG]
Warrington E. K., and Weiskrantz L. (1973) An analysis of short-term and long-term memory defects in man. In: Deutsch J. A. (ed.), The physiological basis of memory. New York, Academic Press. [RPK]
Watson J. B. (1901) Kinaesthetic and organic sensations: Their role in the reactions of the white rat to the maze. Psychological Review, monogr. suppl. 33, pp. 43142. [RJD]
Webster D. B., and Voneida T. J. (1964) Learning deficits following hippo-campal lesions in split-brain cats. Experimental Neurology, 10: 170182. [AG, RHJO'K]
Whishaw I. Q., and Vanderwolf C. H. (1973) Hippocampal EEG and behavior: Changes in amplitude and frequency of RSA (theta rhythm) associated with spontaneous and learned movement patterns in rats and cats. Behavioral Biology, 8: 461484. [JO'K, CHV]
Wickelgren W. A. (1979) Chunking and consolidation: A theoretical synthesis of semantic networks, configuring in conditioning, S-R versus cognitive learning, normal forgetting, the amnesic syndrome and the hippocampal arousal system. Psychological Review, 86: 4460. [LRS]
Wikmark R. G. W., Divac I., & Weiss R. (1973) Retention of spatial delayed alternation in rats with lesions in the frontal lobes. Brain, Behavior, and Evolution, 8: 329339. [GJT]
Williams M. D. (1977) Search: Some observations on the process of retrieval from very long term memory. Ph.D. thesis, Univ. of California, San Diego. [JO'K]
Winocur G., and Breckenridge C. B. (1973) Cue-dependent behavior of hippocampally damaged rats in a complex maze. Journal of Comparative and Physiological Psychology, 82: 512522. [RJD]
Winocur G., and Olds J. (1978) Effects of context manipulation on memory and reversal learning in rats with hippocampal lesions. Journal of Comparative and Physiological Psychology, 92: 312321. [JO'K]
Winson J. (1972) Interspecies differences in the occurrence of theta. Behavioral Biology, 7: 479487. [JEH]
Winson J. (1976a) Hippocampal theta rhythm. I. Depth profiles in the curarized rat. Brain Research 103: 5770. [JO'K]
Winson J. (1976b) Hippocampal theta rhythm. II. Depth profiles in the freely moving rabbit. Brain Research 103: 7180. [JO'K]
Winson J. (1976c) Topographic patterns of hippocampal theta rhythm in freely moving rat and rabbit. In De France J. F. (ed.), The septal nuclei, pp. 463480. New York: Plenum Press. [JO'K]
Winson J. (1978) Loss of hippocampal theta rhythm results in spatial memory deficit in the rat. Science, 201: 160163. [RJD]
Woodruff M. L., and Bailey S. D. (1979) Hippocampal lesions and immobility responses in the rat. Physiological Psychology, 7: 254258. [JO'K]
Woodruff M. L., Hatton D. C., and Meyer M. E. (1975) Hippocampal ablation prolongs immobility response in rabbits (Oryctolagus cuniculus). Journal of Comparative and Physiological Psychology, 88: 329334. [JO'K]
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Behavioral and Brain Sciences
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