Skip to main content
×
×
Home

Trinucleotide repeat disorders: An interesting interface between psychiatry and medicine

  • Justin Barron and Reza Kiani
Summary

The discovery of conditions resulting from the expansion of unstable trinucleotide repeats, with their neuropsychiatric presentations crossing the boundaries of different specialties, provides ample opportunity for research and liaison work between medical and psychiatric subspecialties. Clinicians’ awareness of the presentations and genetic basis of these conditions improves management strategies and the quality of life of patients and their carers.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Trinucleotide repeat disorders: An interesting interface between psychiatry and medicine
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Trinucleotide repeat disorders: An interesting interface between psychiatry and medicine
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Trinucleotide repeat disorders: An interesting interface between psychiatry and medicine
      Available formats
      ×
Copyright
Corresponding author
Dr Reza Kiani, Agnes Unit, 400 Anstey Lane, Leicester LE7 7GL, UK. Email: Reza.Kiani@leicspart.nhs.uk
Footnotes
Hide All

Declaration of Interest

None

Footnotes
References
Hide All
Baig, SS, Strong, M, Rosser, E, et al (2016) 22 years of predictive testing for Huntington's disease: the experience of the UK Huntington's Prediction Consortium. European Journal of Human Genetics, 24: 1396–402.
Cornish, K, Turk, J, Hagerman, R (2008) The fragile X continuum: new advances and perspectives. Journal of Intellectual Disability Research, 52: 469–82.
Jauhar, S, Ritchie, S (2010) Psychiatric and behavioural manifestations of Huntington's disease. Advances in Psychiatric Treatment, 16: 168–75.
McCary, LM, Roberts, JE (2013) Early identification of autism in fragile X syndrome: a review. Journal of Intellectual Disability Research, 57: 803–14.
O'Donnell, W, Warren, S (2002) A decade of molecular studies of fragile X syndrome. Annual Review of Neuroscience, 25: 315–38.
Orr, HT, Zoghbi, HY (2007) Trinucleotide repeat disorders. Annual Review of Neuroscience, 30: 575621.
Paulsen, JS, Hoth, KF, Nehl, C, et al (2005) Critical periods of suicide risk in Huntington's disease. American Journal of Psychiatry, 162: 725–31.
Ross, CA, Tabrizi, SJ (2011) Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurology, 10: 8398.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

BJPsych Advances
  • ISSN: 2056-4678
  • EISSN: 2056-4686
  • URL: /core/journals/bjpsych-advances
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 47 *
Loading metrics...

Abstract views

Total abstract views: 47 *
Loading metrics...

* Views captured on Cambridge Core between 2nd January 2018 - 22nd April 2018. This data will be updated every 24 hours.

Trinucleotide repeat disorders: An interesting interface between psychiatry and medicine

  • Justin Barron and Reza Kiani
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *