1Insel, T, Cuthbert, B, Garvey, M, Heinssen, R, Pine, DS, Quinn, K, et al. Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders. American Psychiatric Association, 2010.
2Hasler, G, Drevets, WC, Manji, HK, Charney, DS. Discovering endophenotypes for major depression. Neuropsychopharmacology 2004; 29: 1765–81.
3Der-Avakian, A, Markou, A. The neurobiology of anhedonia and other reward-related deficits. Trends Neurosci 2012; 35: 68–77.
4Davey, CG, Yücel, M, Allen, NB. The emergence of depression in adolescence: development of the prefrontal cortex and the representation of reward. Neurosci Biobehav Rev 2008; 32: 1–19.
5Forbes, EE, Ryan, ND, Phillips, ML, Manuck, SB, Worthman, CM, Moyles, DL, et al. Healthy adolescents’ neural response to reward: associations with puberty, positive affect, and depressive symptoms. J Am Acad Child Adolesc Psychiatry 2010; 49: 162–72.e5.
6Joiner, TE, Lewinsohn, PM, Seeley, JR. The core of loneliness: lack of pleasurable engagement - more so than painful disconnection - predicts social impairment, depression onset, and recovery from depressive disorders among adolescents. J Pers Assess 2002; 79: 472–91.
7Gabbay, V, Johnson, AR, Alonso, CM, Evans, LK, Babb, JS, Klein, RG. Anhedonia, but not irritability, is associated with illness severity outcomes in adolescent major depression. J Child Adolesc Psychopharmacol 2015; 25: 194–200.
8Bakker, JM, Goossens, L, Lange, I, Michielse, S, Schruers, K, Lieverse, R, et al. Real-life validation of reduced reward processing in emerging adults with depressive symptoms. J Abnorm Psychol 2017; 126: 713–25.
9McCabe, C. Linking anhedonia symptoms with behavioural and neural reward responses in adolescent depression. Curr Opin Behav Sci 2018; 22: 143–51.
10Gard, DE, Kring, AM, Gard, MG, Horan, WP, Green, MF. Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophr Res 2007; 93: 253–60.
11Forbes, EE, Hariri, AR, Martin, SL, Silk, JS, Moyles, DL, Fisher, PM, et al. Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder. Am J Psychiatry 2009; 166: 64–73.
12Hanson, JL, Hariri, AR, Williamson, DE. Blunted ventral striatum development in adolescence reflects emotional neglect and predicts depressive symptoms. Biol Psychiatry 2015; 78: 598–605.
13Auerbach, RP, Admon, R, Pizzagalli, DA. Adolescent depression: stress and reward dysfunction. Harv Rev Psychiatry 2014; 22: 139–48.
14Belden, AC, Irvin, K, Hajcak, G, Kappenman, ES, Kelly, D, Karlow, S, et al. Neural correlates of reward processing in depressed and healthy preschool-age children. J Am Acad Child Adolesc Psychiatry 2016; 55: 1081–9.
15Argyropoulos, SV, Nutt, DJ. Anhedonia revisited: is there a role for dopamine-targeting drugs for depression? J Psychopharmacol 2013; 27: 869–77.
16Zimmerman, M, McGlinchey, JB, Young, D, Chelminski, I. Diagnosing major depressive disorder introduction: an examination of the DSM-IV diagnostic criteria. J Nerv Ment Dis 2006; 194: 151–4.
17Treadway, MT, Zald, DH. Reconsidering anhedonia in depression: lessons from translational neuroscience. Neurosci Biobehav Rev 2011; 35: 537–55.
18Yang, XH, Huang, J, Zhu, CY, Wang, YF, Cheung, EFC, Chan, RCK, et al. Motivational deficits in effort-based decision making in individuals with subsyndromal depression, first-episode and remitted depression patients. Psychiatry Res 2014; 220: 874–82.
19McCabe, C, Cowen, PJ, Harmer, CJ. Neural representation of reward in recovered depressed patients. Psychopharmacology (Berl) 2009; 205: 667–77.
20McCabe, C, Woffindale, C, Harmer, CJ, Cowen, PJ. Neural processing of reward and punishment in young people at increased familial risk of depression. Biol Psychiatry 2012; 72: 588–94.
21Rzepa, E, Fisk, J, McCabe, C. Blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology. J Psychopharmacol 2017; 31: 303–31.
22Kaya, S, McCabe, C. What role does the prefrontal cortex play in the processing of negative and positive stimuli in adolescent depression? Brain Sci 2019; 9: 104.
23Beck, AT, Steer, RA, Ball, R, Ranieri, WF. Comparison of Beck Depression Inventories-IA and -II in psychiatric outpatients. J Pers Assess 1996; 67: 588–97.
24Ancold, A, Costello, EJ, Messer, SC, Pickles, A, Winder, F, Silver, D. Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents. Int J Methods Psychiatr Res 1995; 5: 237–49.
25Gard, DE, Gard, MG, Kring, AM, John, OP. Anticipatory and consummatory components of the experience of pleasure: A scale development study. J Res Pers 2006; 40: 1086–102.
26McCabe, C, Mishor, Z, Cowen, PJ, Harmer, CJ. Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. Biol Psychiatry 2010; 67: 439–45.
27Dean, Z, Horndasch, S, Giannopoulos, P, McCabe, C. Enhanced neural response to anticipation, effort and consummation of reward and aversion during bupropion treatment. Psychol Med 2016; 46: 2263–74.
28Salamone, JD, Yohn, SE, Lopez-Cruz, L, San Miguel, N, Correa, M. Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology. Brain 2016; 139: 1325–47.
29Bylsma, LM, Morris, BH, Rottenberg, J. A meta-analysis of emotional reactivity in major depressive disorder. Clin Psychol Rev 2008; 28: 676–91.
30Cavanna, AE, Trimble, MR. The precuneus: a review of its functional anatomy and behavioural correlates. Brain 2006; 129: 564–83.
31Lemogne, C, le Bastard, G, Mayberg, H, Volle, E, Bergouignan, L, Lehéricy, S, et al. In search of the depressive self: extended medial prefrontal network during self-referential processing in major depression. Soc Cogn Affect Neurosci 2009; 4: 305–12.
32Fitzgerald, PB, Laird, AR, Maller, J, Daskalakis, ZJ. A meta-analytic study of changes in brain activation in depression. Hum Brain Mapp 2007; 29: 683–95.
33Cheng, W, Rolls, ET, Qiu, J, Yang, D, Ruan, H, Wei, D, et al. Functional connectivity of the precuneus in unmedicated patients with depression. Biol Psychiatry 2018; 3: 1040–9.
34Sheline, YI, Price, JL, Yan, Z, Mintun, MA. Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus. Proc Natl Acad Sci USA 2010; 107: 11020–25.
35Fonseka, TM, MacQueen, GM, Kennedy, SH. Neuroimaging biomarkers as predictors of treatment outcome in major depressive disorder. J Affect Dis 2018; 233: 21–35.
36Chang, LJ, Yarkoni, T, Khaw, MW, Sanfey, AG. Decoding the role of the insula in human cognition: functional parcellation and large-scale reverse inference. Cereb Cortex 2013; 23: 739–49.
37Kusumoto-Yoshida, I, Liu, H, Chen, BT, Fontanini, A, Bonci, A. Central role for the insular cortex in mediating conditioned responses to anticipatory cues. Proc Natl Acad Sci USA 2015; 112: 1190–5.
38Rogers-Carter, MM, Varela, JA, Gribbons, KB, Pierce, AF, McGoey, MT, Ritchey, M, et al. Insular cortex mediates approach and avoidance responses to social affective stimuli. Nat Neurosci 2018; 21: 404.
39McGrath, CL, Kelley, ME, Holtzheimer, PE, Dunlop, BW, Craighead, WE, Franco, AR, et al. Toward a neuroimaging treatment selection biomarker for major depressive disorder. JAMA Psychiatry 2013; 70: 821–9.
40Rzepa, E, Fisk, J, McCabe, C. Blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology. J Psychopharmacol 2017; 31: 303–11.
41Carretie, L, Rios, M, de la Gandara, BS, Tapia, M, Albert, J, Lopez-Martin, S, et al. The striatum beyond reward: caudate responds intensely to unpleasant pictures. Neuroscience 2009; 164: 1615–22.
42Treadway, MT, Bossaller, NA, Shelton, RC, Zald, DH. Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia. J Abnorm Psychol 2012; 121: 553–8.
43Sherdell, L, Waugh, CE, Gotlib, IH. Anticipatory pleasure predicts motivation for reward in major depression. J Abnorm Psychol 2012; 121: 51–60.
44Hoshi, E. Functional specialization within the dorsolateral prefrontal cortex: a review of anatomical and physiological studies of non-human primates. Neurosci Res 2006; 54: 73–84.
45Liu, W, Mao, Y, Wei, D, Yang, J, Du, X, Xie, P, et al. Structural asymmetry of dorsolateral prefrontal cortex correlates with depressive symptoms: evidence from healthy Individuals and patients with major depressive disorder. Neurosci Bull 2016; 32: 217–26.
46Murphy, FC, Nimmo-Smith, I, Lawrence, AD. Functional neuroanatomy of emotions: a meta-analysis. Cogn Affect Behav Neurosci 2003; 3: 207–33.
47Fettes, P, Schulze, L, Downar, J. Cortico-striatal-thalamic loop circuits of the orbitofrontal cortex: promising therapeutic targets in psychiatric illness. Front Syst Neurosci 2017; 11: 25.
48Kringelbach, ML, Rolls, ET. The functional neuroanatomy of the human orbitofrontal cortex: evidence from neuroimaging and neuropsychology. Prog Neurobiol 2004; 72: 341–72.
49Rolls, ET. A non-reward attractor theory of depression. Neurosci Biobehav Rev 2016; 68: 47–58.
50O'Doherty, J, Dayan, P, Schultz, J, Deichmann, R, Friston, KJ, Dolan, RJ. Dissociable roles of ventral and dorsal striatum in instrumental conditioning. Science 2004; 304: 452–4.
51Park, IH, Lee, BC, Kim, JJ, Kim, JI, Koo, MS. Effort-based reinforcement processing and functional connectivity underlying amotivation in medicated patients with depression and schizophrenia. J Neurosci 2017; 37: 4370–80.