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A population study of Norwegian psychiatric patients referred for clinical brain scanning

  • Mona K. Beyer (a1), Turi O. Dalaker (a2), Ole J. Greve (a2), Siv E. Pignatiello (a3) and Ingrid Agartz (a4)...
Abstract
Background

Patients with psychiatric conditions are often referred for a brain scan during the course of their diagnostic workup.

Aims

The aim of our study is to determine frequency and type of organic brain pathology, the relationship to age, gender and psychiatric diagnosis.

Method

We investigated magnetic resonance imaging and computed tomography brain scans from consecutively referred patients over a 10-year period (January 2002-December 2011). The reasons for referral, estimated psychiatric diagnosis, and the pathology discovered for each patient were registered.

Results

A total of 34% of patients demonstrated organic brain pathology, of which 32.8% were considered clinically relevant. This represents a higher frequency of relevant pathology than reported in healthy subjects. Age (P < 0.001) and diagnosis (P = 0.016) were the most important determinants for frequency of pathological findings.

Conclusions

Brain imaging in clinical psychiatry resulted in approximately 30% positive findings mainly associated with increasing pathologies with age, but also with diagnosis.

Declaration of interest

Both T.O.D. and M.K.B. have received honorary from Novartis for scientific lectures about multiple sclerosis. M.K.B. also received honoraria from Biogen for scientific lectures. The other authors have no conflicts of interest.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Corresponding author
Correspondence: Mona K. Beyer, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital, PO box 4959 Nydalen, 0424 Oslo. Email: monbey@ous-hf.no
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A population study of Norwegian psychiatric patients referred for clinical brain scanning

  • Mona K. Beyer (a1), Turi O. Dalaker (a2), Ole J. Greve (a2), Siv E. Pignatiello (a3) and Ingrid Agartz (a4)...
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