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Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study

  • Gerrie-Cor M. Herber-Gast (a1) (a2), Marijke Boersma (a1), W. M. Monique Verschuren (a1) (a3), Coen D. A. Stehouwer (a2), Ron T. Gansevoort (a4), Stephan J. L. Bakker (a4) and Annemieke M. W. Spijkerman (a1)...
Abstract

Emerging evidence suggests that diet and renal function are related. Little is known, however, about the association of consumption of whole grains, fruit and vegetables with urinary albumin:creatinine ratio (ACR) and changes in estimated glomerular filtration rate (eGFR). We investigated this in a population-based cohort aged 26–65 years. Data were from 3787 participants from the Doetinchem cohort study, who were examined ≥3 times, 5 years apart. Consumption of food groups was assessed at each round with a validated FFQ. GFR was estimated at each round from routinely measured cystatin C and creatinine using the Chronic Kidney Disease-Epidemiology (CKD-EPI) equation. ACR was measured at the last round. Generalised estimated equation models were performed to examine associations with changes in eGFR. Linear regression was used to examine associations with ACR. Adjustments were made for covariates related to lifestyle, biological factors and diet. Mean baseline eGFR was 104·5 (sd 13·7) and mean annual decline was −0·95 (sd 0·67) ml/min per 1·73 m2 over a 15-year follow-up. A trend was observed towards slightly less annual decline in eGFR among those with higher consumption of whole grains (P=0·06). This association, however, was attenuated and no longer significant in multivariate models (P=0·29). Consumption of fruit and vegetables was not associated with changes in eGFR and urinary ACR. In conclusion, consumption of whole grains, fruit and vegetables is not associated with changes in eGFR and mean ACR. As this was the first longitudinal study into this association in the general population, and as results are only partially in line with related studies, further research is recommended.

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This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
* Corresponding author: G.-C. M. Herber-Gast, fax +31 30 274 4407, email Gerrie-Cor.Herber@rivm.nl
References
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1. Jha, V, Garcia-Garcia, G, Iseki, K, et al. (2013) Chronic kidney disease: global dimension and perspectives. Lancet 382, 260272.
2. National Kidney Foundation (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39, S1S266.
3. Herber-Gast, GC, van Essen, H, Verschuren, WM, et al. (2016) Coffee and tea consumption in relation to estimated glomerular filtration rate: results from the population-based longitudinal Doetinchem Cohort Study. Am J Clin Nutr 103, 13701377.
4. Herber-Gast, GM, Biesbroek, S, Verschuren, WM, et al. (2016) Association of dietary protein and dairy intakes and change in renal function: results from the population-based longitudinal Doetinchem cohort study. Am J Clin Nutr 104, 17121719.
5. Chanson-Rolle, A, Meynier, A, Aubin, F, et al. (2015) Systematic review and meta-analysis of human studies to support a quantitative recommendation for whole grain intake in relation to type 2 diabetes. PLOS ONE 10, e0131377.
6. Cooper, AJ, Forouhi, NG, Ye, Z, et al. (2012) Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis. Eur J Clin Nutr 66, 10821092.
7. Dauchet, L, Amouyel, P, Hercberg, S, et al. (2006) Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr 136, 25882593.
8. He, FJ, Nowson, CA & MacGregor, GA (2006) Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. Lancet 367, 320326.
9. Mellen, PB, Walsh, TF & Herrington, DM (2008) Whole grain intake and cardiovascular disease: a meta-analysis. Nutr Metab Cardiovasc Dis 18, 283290.
10. Nettleton, JA, Steffen, LM, Palmas, W, et al. (2008) Associations between microalbuminuria and animal foods, plant foods, and dietary patterns in the Multiethnic Study of Atherosclerosis. Am J Clin Nutr 87, 18251836.
11. Chen, CH, Yang, WC, Hsiao, YH, et al. (2016) High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease. Nutrition 32, 236241.
12. Jun, M, Venkataraman, V, Razavian, M, et al. (2012) Antioxidants for chronic kidney disease. Cochrane Database Syst Rev, issue 10, CD008176.
13. Krishnamurthy, VM, Wei, G, Baird, BC, et al. (2012) High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease. Kidney Int 81, 300306.
14. Massy, ZA & Drueke, TB (2012) Magnesium and outcomes in patients with chronic kidney disease: focus on vascular calcification, atherosclerosis and survival. Clin Kidney J 5, i52i61.
15. Khatri, M, Moon, YP, Scarmeas, N, et al. (2014) The association between a Mediterranean-style diet and kidney function in the Northern Manhattan Study cohort. Clin J Am Soc Nephrol 9, 18681875.
16. Foster, MC, Hwang, SJ, Massaro, JM, et al. (2015) Lifestyle factors and indices of kidney function in the Framingham Heart Study. Am J Nephrol 41, 267274.
17. Verschuren, WM, Blokstra, A, Picavet, HS, et al. (2008) Cohort profile: the Doetinchem Cohort Study. Int J Epidemiol 37, 12361241.
18. NEVO (Nederlands Voedingsstoffen bestand) Foundation (1996) Dutch Food Composition Database (NEVO). Den Haag, The Netherlands: Voorlichtingsbureau voor de voeding.
19. Cooper, AJ, Forouhi, NG, Ye, Z, et al. (2012) Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis. Eur J Clin Nutr 66, 10821092.
20. Tabak, C, Smit, HA, Heederik, D, et al. (2001) Diet and Qchronic obstructive pulmonary disease: independent beneficial effects of fruits, whole grains, and alcohol (the MORGEN study). Clin Exp Allergy 31, 747755.
21. Ocke, MC, Bueno-de-Mesquita, HB, Goddijn, HE, et al. (1997) The Dutch EPIC food frequency questionnaire. I. Description of the questionnaire, and relative validity and reproducibility for food groups. Int J Epidemiol 26, Suppl. 1, S37S48.
22. Twisk, JWR (2003) Applied Longitudinal Data Analysis for Epidemiology: A Practical Guide. Cambridge: Cambridge University Press.
23. Vart, P, Bakker, SJ, Schottker, B, et al. (2015) Relevance of correction for drift and day-to-day variation in cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with independent replication in the ESTHER cohort. Clin Chem Lab Med 53, 13811390.
24. Inker, LA, Schmid, CH, Tighiouart, H, et al. (2012) Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med 367, 2029.
25. US Department of Health and Human Services & US Department of Agriculture (2005) Dietary Guidelines for Americans. Washington, DC: Government Printing Office.
26. Wareham, NJ, Jakes, RW, Rennie, KL, et al. (2003) Validity and repeatability of a simple index derived from the short physical activity questionnaire used in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Public Health Nutr 6, 407413.
27. Nooyens, AC, Milder, IE, van Gelder, BM, et al. (2015) Diet and cognitive decline at middle age: the role of antioxidants. Br J Nutr 113, 14101417.
28. Willett, WC, Howe, GR & Kushi, LH. (1997) Adjustment for total energy intake in epidemiologic studies. Am J Clin Nutr 65, 1220S1228S; discussion 1229S–1231S.
29. Ma, J, Jacques, PF, Hwang, SJ, et al. (2016) Dietary Guideline Adherence Index and kidney measures in the Framingham Heart Study. Am J Kidney Dis 68, 703715.
30. Lin, J, Fung, TT, Hu, FB, et al. (2011) Association of dietary patterns with albuminuria and kidney function decline in older white women: a subgroup analysis from the Nurses’ Health Study. Am J Kidney Dis 57, 245254.
31. Oude Griep, LM, Geleijnse, JM, Kromhout, D, et al. (2010) Raw and processed fruit and vegetable consumption and 10-year coronary heart disease incidence in a population-based cohort study in the Netherlands. PLOS ONE 5, e13609.
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British Journal of Nutrition
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