Skip to main content
×
Home
    • Aa
    • Aa

Studies on calcium absorption from milk using a double-label stable isotope technique

  • Susan J. Fairweather-Tait (a1), Amanda Johnson (a1), J. Eagles (a1), Smita Ganatra (a2), H. Kennedy (a3) and M. I. Gurr (a2)...
Abstract

Calcium absorption was measured in ten male volunteers from skimmed milk, Ca-enriched skimmed milk or watercress (Nasturtium officinale) soup. The foods were labelled extrinsically with 30 mg 44Ca. Shortly after consuming the labelled meal, each subject was given an intravenous injection of 3 mg 42ca. Fractional absorption from the oral dose was determined from plasma and urine samples collected 24–72 h later, using fast atom bombardment mass spectrometry to measure isotope ratios. The values for urine and plasma were in good agreement. Mean percentage absorption was 45.5 (SEM 1.9)% from the skimmed milk, 35.7 (SEM 4.7) % from the Ca-enriched milk and 27.4 (SEM 1.9) % from the watercress soup. The effect of consuming 568 ml (1 pint) Ca-enriched milk each day for 4 weeks on the efficiency of absorption of Ca was studied. Although there was no statistically significant difference between Ca absorption before and after the supplementation period, the results were considered to be somewhat inconclusive due to the small number of subjects and wide individual variation in Ca absorption.

    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Studies on calcium absorption from milk using a double-label stable isotope technique
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Studies on calcium absorption from milk using a double-label stable isotope technique
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Studies on calcium absorption from milk using a double-label stable isotope technique
      Available formats
      ×
Copyright
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

S. J. Birge , W. A. Peck , M. Berman & G. D. Whedon (1969). Study of calcium absorption in man: a kinetic analysis and physiologic model. Journal of Clinical Investigations 48, 17051713.

P. Charley & P. Saltman (1963). Chelation of calcium by lactose: its role in transport mechanisms. Science 139, 12051206.

R. P. Heaney & T. G. Skillman (1971). Calcium metabolism in normal human pregnancy. Journal of Clinical Endocrinology 33, 661669.

L. S. Hillman , E. Tack , D. G. Covell , N. E. Vieira & A. L. Yergey (1988). Measurement of true calcium absorption in premature infants using intravenous 46Ca and oral 44Ca. Pediatric Research 23, 589594.

X. Jiang & D. L. Smith (1987). Quantitation of stable isotopic tracer of calcium by fast atom bombardment mass spectrometry. Analytical Chemistry 59, 25702574.

J. Kocián , I. Skála & K. Bakos (1973). Calcium absorption from milk and lactose-free milk in healthy subjects and patients with lactose intolerance. Digestion 9, 317324.

O. J. Malm (1953). On phosphate and phosphoric acid as dietary factors in the calcium balance of man. Scandinavian Journal of Clinical and Laboratory Investigation 5, 7584.

M. Nelson , G. F. Hague , C. Cooper & V. W. Bunker (1988). Calcium intake in the elderly: validation of a dietary questionnaire. Journal of Human Nutrition and Dietetics 1, 115127.

M. J. Nicar & Y. C. Pak (1985). Calcium bioavailability from calcium carbonate and calcium citrate. Journal of Clinical Endocrinology and Metabolism 61, 391393.

D. A. Norman , J. S. Fordtran , L. J. Brinkley , J. E. Zerwekh , M. J. Nicar , S. M. Strowig & C. Y. C. Pak (1981). Jejunal and ileal adaptation to alterations in dietary calcium. Journal of Clinical Investigation 67, 15991603.

D. L. Smith (1983). Determination of stable isotopes of calcium in biological fluids by fast atom bombardment mass spectrometry. Analytical Chemistry 55, 23912393.

D. L. Smith , C. Atkin & C. Westenfelder (1985). Stable isotopes of calcium as tracers: methodology. Clinica Chimica Acta 146, 97101.

C. M. Weaver , B. R. Martin , D. L. Smith , J. V. Chambers & C. H. Noller (1988). Endogenous labelling of bovine milk with the stable isotope 44Ca. Nutrition Research 8, 11831189.

A. L. Yergey , N. E. Vieira & D. G. Covell (1987). Direct measurement of dietary functional absorption using calcium isotopic tracers. Biomedical and Environmental Mass Spectrometry 14, 603607.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: