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Effect of caffeine on zinc absorption and Zn concentration in rat tissue

  • Magdalena J. Rossowska (a1) and Tetsuo Nakamoto (a1)
  • DOI: http://dx.doi.org/10.1079/BJN19900055
  • Published online: 01 March 2007
Abstract

The purposes of the present study were to determine whether caffeine has an effect on zinc absorption and tissue levels of Zn. Under anaesthesia, one side of the intestine of female rats was connected to infusion pumps and an infused solution (first caffeine and later Zn solution) was collected from the other side of the intestine using either 300 mm or the whole small intestine to determine Zn absorption. In a further study, different doses of caffeine solution were injected directly into the femoral vein and a saline or Zn solution was infused into the intestine to measure Zn absorption and tissue Zn concentrations. The results consistently showed that the caffeine solution infused into the intestine did not affect intestinal Zn absorption nor was absorption affected by the direct injection of caffeine into the vein. In contrast, injection of different doses of the caffeine solution significantly decreased Zn tissue levels for the heart only. Calcium concentrations in the heart tissue were also decreased, but not magnesium concentrations. Tissue Zn levels recovered immediately on infusion of a Zn solution into the intestine.

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W. J. Bettger & B. L. O'Dell (1981). A critical physiological role of zinc in the structure and function of biomembranes. Life Sciences 28, 14251438.

J. Blanchard & S. J. A. Sawers (1983). The absolute bioavailability of caffeine in man. European Journal of Pharmacology 24, 9398.

A. P. Carvalho (1968). Effects of potentiators of muscular contraction on binding of cations by sarcoplasmic reticulum. Journal of General Physiology 51, 427442.

R. J. Cousins , K. T. Smith , M. L. Failla & L. A. Markowitz (1978). Origin of low molecular weight zinc-binding complexes from rat intestine. Life Science 23, 18191826.

G. Meissner , E. Darling & J. Eveleth (1986). Kinetics of rapid Ca2+, Mg2+, and adenine nucleotides. Biochemistry 25, 236244.

T. Nakamoto , S. Grant & M. Yazdani (1989 a). The effects of maternal contents of fetal rat bone. Research in Experimental Medicine 189, 275280.

T. Nakamoto , A. D. Hartman & F. Joseph Jr (1989 b). Interaction between caffeine intake and nutritional status on growing brains in newborn rats. Annals of Nutrition and Metabolism 33, 9299.

M. P. Richards & R. J. Cousins (1975). Mammalian zinc homeostasis: requirement for RNA and metallothionein synthesis. Biochemical and Biophysical Research Communications 64, 12151223.

A. M. Rubtsov & A. J. Murphy (1988). Caffeine interaction with Ca-release channels of heavy sarcoplasmic reticulum. Evidence that 170 kD Ca-binding protein is a caffeine receptor of the Ca-channels. Biochemical and Biophysical Research Communications 154, 462468.

T. E. Temples , D. J. Geoffray , T. Nakamoto , A. D. Hartman & H. I. Miller (1985). Effect of chronic caffeine intake on myocardial function during early growth. Pediatric Research 21, 391395.

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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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