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    Scheurer, J M Gray, H L Demerath, E W Rao, R and Ramel, S E 2016. Diminished growth and lower adiposity in hyperglycemic very low birth weight neonates at 4 months corrected age. Journal of Perinatology, Vol. 36, Issue. 2, p. 145.

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    Clark, Reese H. Olsen, Irene E. and Spitzer, Alan R. 2014. Assessment of Neonatal Growth in Prematurely Born Infants. Clinics in Perinatology, Vol. 41, Issue. 2, p. 295.

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    Au, Cheryl P. Raynes-Greenow, Camille H. Turner, Robin M. Carberry, Angela E. and Jeffery, Heather 2013. Fetal and maternal factors associated with neonatal adiposity as measured by air displacement plethysmography: A large cross-sectional study. Early Human Development, Vol. 89, Issue. 10, p. 839.


Effect of sex and gestational age on neonatal body composition

  • Laure Simon (a1), Paula Borrego (a2), Dominique Darmaun (a2), Arnaud Legrand (a3), Jean-Christophe Rozé (a1) (a2) (a3) and Anne Chauty-Frondas (a1) (a2) (a3)
  • DOI:
  • Published online: 12 July 2012

To determine the effects of length of gestation and sex on infant body composition, air displacement plethysmography was performed in forty-six full-term neonates at 3 d of life and during the week prior to hospital discharge in 180 preterm neonates. Fat mass, as a percentage of body weight, was higher in preterm than in term infants (13·4 (sd 4·2) v. 10·1 (sd 3·7) %, respectively; P= 0·001). The absolute amount of fat mass did not differ between preterm and full-term newborns (323 (sd 126) v. 335 (sd 138) g; P= 0·58), whereas lean body mass was lower in preterm than in term infants (2055 (sd 280) v. 2937 (sd 259) g, respectively; P< 0·001). Among full-term infants, fat mass was higher in females than in males (11·1 (sd 3·7) v. 9·0 (sd 3·3) %, respectively; P= 0·047), whereas we did not observe any sex difference in preterm infants (13·5 (sd 4·1) v. 13·4 (sd 4·3) %; P= 0·89). Our data suggest that by the time they are discharged from hospital: (1) preterm infants have a higher percentage of body fat than term neonates and (2) this is presumably due to a lesser accretion in lean body mass in the first few weeks of extra-uterine life, particularly in boys.

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*Corresponding author: Professor J.-C. Rozé, fax +33 2 53 48 20 03, email
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