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1 MP Murphy (2009) How mitochondria produce reactive oxygen species. Biochem J 417, 1–13.
2 K Apel & H Hirt (2004) Reactive oxygen species: metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol 55, 373–399.
3 A Virdis , L Ghiadoni , C Giannarelli , et al. (2010) Endothelial dysfunction and vascular disease in later life. Maturitas 67, 20–24.
4 AC Kaliora , GV Dedoussis & H Schmidt (2006) Dietary antioxidants in preventing atherogenesis. Atherosclerosis 187, 1–17.
5 IM Rietjens , MG Boersma , L Haan , et al. (2002) The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids. Environ Toxicol Pharmacol 11, 321–333.
6 Y Plantinga , L Ghiadoni , A Magagna , et al. (2007) Supplementation with vitamins C and E improves arterial stiffness and endothelial function in essential hypertensive patients. Am J Hypertens 20, 392–397.
8 JA Beckman , AB Goldfine , MB Gordon , et al. (2003) Oral antioxidant therapy improves endothelial function in type 1 but not type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 285, H2392–H2398.
9 S Kinlay , D Behrendt , JC Fang , et al. (2004) Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function. J Am Coll Cardiol 43, 629–634.
10 EB Rimm , MJ Stampfer , A Ascherio , et al. (1993) Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 328, 1450–1456.
12Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico (1999) Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354, 447–455.
15 DD Waters , EL Alderman , J Hsia , et al. (2002) Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial. JAMA 288, 2432–2440.
16 PM Vanhoutte , H Shimokawa , EH Tang , et al. (2009) Endothelial dysfunction and vascular disease. Acta Physiol (Oxf) 196, 193–222.
19 JPT Higgins & S Green (2008) Guide to the contents of a cochrane protocol and review. In Cochrane Handbook for Systematic Reviews of Interventions, pp. 51–79. Chichester: John Wiley & Sons, Ltd.
20 A Liberati , DG Altman , J Tetzlaff , et al. (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339, b2700.
21 M Crowther , W Lim & MA Crowther (2010) Systematic review and meta-analysis methodology. Blood 116, 3140–3146.
23 SP Hozo , B Djulbegovic & I Hozo (2005) Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 5, 13.
26 L Franzini , D Ardigo , S Valtuena , et al. (2012) Food selection based on high total antioxidant capacity improves endothelial function in a low cardiovascular risk population. Nutr Metab Cardiovasc Dis 22, 50–57.
28 F Khan , S Ray , AM Craigie , et al. (2014) Lowering of oxidative stress improves endothelial function in healthy subjects with habitually low intake of fruit and vegetables: a randomized controlled trial of antioxidant- and polyphenol-rich blackcurrant juice. Free Radic Biol Med 72, 232–237.
17 T Gori & T Munzel (2011) Oxidative stress and endothelial dysfunction: therapeutic implications. Ann Med 43, 259–272.
31 JM May (2000) How does ascorbic acid prevent endothelial dysfunction? Free Radic Biol Med 28, 1421–1429.
34 D Jurk , C Wilson , JF Passos , et al. (2014) Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat Commun 2, 4172.
35 M El Assar , J Angulo , S Vallejo , et al. (2012) Mechanisms involved in the aging-induced vascular dysfunction. Front Physiol 3, 132.
36 FJ Pashkow (2011) Oxidative stress and inflammation in heart disease: do antioxidants have a role in treatment and/or prevention? Int J Inflam 2011, 514623.
37 JA Vita , JF Keaney Jr, MG Larson , et al. (2004) Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study. Circulation 110, 3604–3609.
39 AW Ashor , J Lara , JC Mathers , et al. (2014) Effect of vitamin C on endothelial function in health and disease: a systematic review and meta-analysis of randomised controlled trials. Atherosclerosis 235, 9–20.
40 MG Traber & JF Stevens (2011) Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med 51, 1000–1013.
41 NR Cook , CM Albert , JM Gaziano , et al. (2007) A randomized factorial trial of vitamins C and E and β-carotene in the secondary prevention of cardiovascular events in women: results from the Women's Antioxidant Cardiovascular Study. Arch Intern Med 167, 1610–1618.
43 M Vardi , S Blum & AP Levy (2012) Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus – natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature. Eur J Intern Med 23, 628–632.
44 R Asleh & AP Levy (2010) Divergent effects of α-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2–2 genotype. Antioxid Redox Signal 12, 209–217.
49 AW Ashor , M Siervo , J Lara , et al. (2014) Antioxidant vitamin supplementation reduces arterial stiffness in adults: a systematic review and meta-analysis of randomized controlled trials. J Nutr 144, 1594–1602.
50 M Zureik , P Galan , S Bertrais , et al. (2004) Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries. Arterioscler Thromb Vasc Biol 24, 1485–1491.
51 D Brubacher , U Moser & P Jordan (2000) Vitamin C concentrations in plasma as a function of intake: a meta-analysis. Int J Vitam Nutr Res 70, 226–237.
52 F Visioli & TM Hagen (2007) Nutritional strategies for healthy cardiovascular aging: focus on micronutrients. Pharmacol Res 55, 199–206.
53 AA Puca , A Carrizzo , F Villa , et al. (2013) Vascular ageing: the role of oxidative stress. Int J Biochem Cell Biol 45, 556–559.
58 ER Miller 3rd, R Pastor-Barriuso , D Dalal , et al. (2005) Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 142, 37–46.
59 M Schurks , RJ Glynn , PM Rist , et al. (2010) Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials. BMJ 341, c5702.