Skip to main content
    • Aa
    • Aa
  • Access
  • Cited by 12
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Coppock, Robert W. and Dziwenka, Margitta 2016. Nutraceuticals.

    Elmann, Anat Beit-Yannai, Elie Telerman, Alona Ofir, Rivka Mordechay, Sharon Erlank, Hilla and Borochov-Neori, Hamutal 2016. Pulicaria incisa infusion attenuates inflammatory responses of brain microglial cells. Journal of Functional Foods, Vol. 25, p. 110.

    Hügel, Helmut M. Jackson, Neale May, Brian Zhang, Anthony L. and Xue, Charlie C. 2016. Polyphenol protection and treatment of hypertension. Phytomedicine, Vol. 23, Issue. 2, p. 220.

    Lau, Sarah Georgousopoulou, Ekavi Kellett, Jane Thomas, Jackson McKune, Andrew Mellor, Duane Roach, Paul and Naumovski, Nenad 2016. The Effect of Dietary Supplementation of Green Tea Catechins on Cardiovascular Disease Risk Markers in Humans: A Systematic Review of Clinical Trials. Beverages, Vol. 2, Issue. 2, p. 16.

    Mankin, Leonard A. 2016. Update in Hypertension Therapy. Medical Clinics of North America, Vol. 100, Issue. 4, p. 665.

    Tomé-Carneiro, Joao and Visioli, Francesco 2016. Polyphenol-based nutraceuticals for the prevention and treatment of cardiovascular disease: Review of human evidence. Phytomedicine, Vol. 23, Issue. 11, p. 1145.

    Ma, Qinghua Chen, Dandan Sun, Hong-Peng Yan, Ning Xu, Yong and Pan, Chen-Wei 2015. Regular Chinese Green Tea Consumption Is Protective for Diabetic Retinopathy: A Clinic-Based Case-Control Study. Journal of Diabetes Research, Vol. 2015, p. 1.

    Ruxton, C. Phillips, F. and Bond, T. 2015. Is tea a healthy source of hydration?. Nutrition Bulletin, Vol. 40, Issue. 3, p. 166.

    San Cheang, Wai Yuen Ngai, Ching Yen Tam, Ye Yu Tian, Xiao Tak Wong, Wing Zhang, Yang Wai Lau, Chi Chen, Zhen Yu Bian, Zhao-Xiang Huang, Yu and Ping Leung, Fung 2015. Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress. Scientific Reports, Vol. 5, p. 10340.

    Serban, Corina Sahebkar, Amirhossein Antal, Diana Ursoniu, Sorin and Banach, Maciej 2015. Effects of supplementation with green tea catechins on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials. Nutrition, Vol. 31, Issue. 9, p. 1061.

    Sirtori, Cesare R. Arnoldi, Anna and Cicero, Arrigo F. G. 2015. Nutraceuticals for blood pressure control. Annals of Medicine, Vol. 47, Issue. 6, p. 447.

    Wang, Yanchun Xing, Fengjun Liu, Rongjuan Liu, Li Zhu, Yu Wen, Yufeng Sun, Wenjie and Song, Ziwei 2015. Isolated Diastolic Hypertension Associated Risk Factors among Chinese in Anhui Province, China. International Journal of Environmental Research and Public Health, Vol. 12, Issue. 4, p. 4395.


Effects of tea intake on blood pressure: a meta-analysis of randomised controlled trials

  • Gang Liu (a1), Xue-Nan Mi (a2), Xin-Xin Zheng (a1), Yan-Lu Xu (a1), Jie Lu (a1) and Xiao-Hong Huang (a1)
  • DOI:
  • Published online: 19 August 2014

The effect of tea intake on blood pressure (BP) is controversial. We performed a meta-analysis of randomised controlled trials to determine the changes in systolic and diastolic BP due to the intake of black and green tea. A systematic search was conducted in MEDLINE, EMBASE and the Cochrane Controlled Trials Register up to May 2014. The weighted mean difference was calculated for net changes in systolic and diastolic BP using fixed-effects or random-effects models. Previously defined subgroup analyses were performed to explore the influence of study characteristics. A total of twenty-five eligible studies with 1476 subjects were selected. The acute intake of tea had no effects on systolic and diastolic BP. However, after long-term tea intake, the pooled mean systolic and diastolic BP were lower by − 1·8 (95 % CI − 2·4, − 1·1) and − 1·4 (95 % CI − 2·2, − 0·6) mmHg, respectively. When stratified by type of tea, green tea significantly reduced systolic BP by 2·1 (95 % CI − 2·9, − 1·2) mmHg and decreased diastolic BP by 1·7 (95 % CI − 2·9, − 0·5) mmHg, and black tea showed a reduction in systolic BP of 1·4 (95 % CI − 2·4, − 0·4) mmHg and a decrease in diastolic BP of 1·1 (95 % CI − 1·9, − 0·2) mmHg. The subgroup analyses showed that the BP-lowering effect was apparent in subjects who consumed tea more than 12 weeks (systolic BP − 2·6 (95 % CI − 3·5, − 1·7) mmHg and diastolic BP − 2·2 (95 % CI − 3·0, − 1·3) mmHg, both P< 0·001). The present findings suggest that long-term ( ≥ 12 weeks) ingestion of tea could result in a significant reduction in systolic and diastolic BP.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the or variations. ‘’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Effects of tea intake on blood pressure: a meta-analysis of randomised controlled trials
      Available formats
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Effects of tea intake on blood pressure: a meta-analysis of randomised controlled trials
      Available formats
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Effects of tea intake on blood pressure: a meta-analysis of randomised controlled trials
      Available formats
Corresponding author
*Corresponding author: X.-H. Huang, fax +86 10 68331730, email
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1 VLRoger , ASGo , DMLloyd-Jones , et al. (2011) Heart disease and stroke statistics – 2011 update: a report from the American Heart Association. Circulation 123, E18E209.

3K Miura , ML Daviglus , AR Dyer , et al. (2001) Relationship of blood pressure to 25-year mortality due to coronary heart disease, cardiovascular diseases, and all causes in young adult men: the Chicago Heart Association Detection Project in Industry. Arch Intern Med 161, 15011508.

4Knaze V1, R Zamora-Ros , L Luján-Barroso , et al. (2012) Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Br J Nutr 108, 10951108.

5 SKuriyama , TShimazu , KOhmori , et al. (2006) Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study. JAMA 296, 12551265.

6JM de Koning Gans , CS Uiterwaal , YT van der Schouw , et al. (2010) Tea and coffee consumption and cardiovascular morbidity and mortality. Arterioscler Thromb Vasc Biol 30, 16651671.

7 DGrassi , GDesideri , PDi Giosia , et al. (2013) Tea, flavonoids, and cardiovascular health: endothelial protection. Am J Clin Nutr 98, S1660S1666.

8JM Hodgson , RJ Woodman , IB Puddey , et al. (2013) Short-term effects of polyphenol-rich black tea on blood pressure in men and women. Food Funct 4, 111115.

9A Belza , S Toubro & A Astrup (2009) The effect of caffeine, green tea and tyrosine on thermogenesis and energy intake. Eur J Clin Nutr 63, 5764.

10 JMHodgson , VBurke & IBPuddey (2005) Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans. J Hypertens 23, 4754.

11 PTQuinlan , JLane , KLMoore , et al. (2000) The acute physiological and mood effects of tea and coffee: the role of caffeine level. Pharmacol Biochem Behav 66, 1928.

13JM Hodgson , IB Puddey , V Burke , et al. (1999) Effects on blood pressure of drinking green and black tea. J Hypertens 17, 457463.

14 SJDuffy , JFKeaneyJr , MHolbrook , et al. (2001) Short and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease. Circulation 104, 151156.

16 KJMukamal , KMacDermott , JAVinson , et al. (2007) A 6-month randomised pilot study of black tea and cardiovascular risk factors. Am Heart J 154, E1E6.

17 DGrassi , TPMulder , RDraijer , et al. (2009) Black tea consumption dose-dependently improves flow-mediated dilation in healthy males. J Hypertens 27, 774781.

18JM Hodgson , IB Puddey , RJ Woodman , et al. (2012) Effects of black tea on blood pressure: a randomised controlled trial. Arch Intern Med 172, 186188.

19 YFukino , MShimbo , NAoki , et al. (2005) Randomised controlled trial for an effect of green tea consumption on insulin resistance and inflammation markers. J Nutr Sci Vitaminol 51, 335342.

20 KDiepvens , EMKovacs , NVogels , et al. (2006) Metabolic effects of green tea and of phases of weight loss. Physiol Behav 87, 185191.

21 TNagao , THase & ITokimitsu (2007) A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity 15, 14731483.

22Y Fukino , A Ikeda , K Maruyama , et al. (2008) Randomised controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities. Eur J Clin Nutr 62, 953960.

23 CHHsu , THTsai , YHKao , et al. (2008) Effect of green tea extract on obese women: a randomised, double-blind, placebo-controlled clinical trial. Clin Nutr 27, 363370.

24 TMatsuyama , YTanaka , IKamimaki , et al. (2008) Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children. Obesity 16, 13381348.

26J Frank , TW George , JK Lodge , et al. (2009) Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men. J Nutr 139, 5862.

27 MPNantz , CARowe , JFBukowski , et al. (2009) Standardized capsule of Camellia sinensis lowers cardiovascular risk factors in a randomised, double-blind, placebo-controlled study. Nutrition 25, 147154.

28 TNagao , SMeguro , THase , et al. (2009) A catechin-rich beverage improves obesity and blood glucose control in patients with type 2 diabetes. Obesity 17, 310317.

30 TSone , SKuriyama , NNakaya , et al. (2011) Randomised controlled trial for an effect of catechin-enriched green tea consumption on adiponectin and cardiovascular disease risk factors. Food Nutr Res (Epublication 1 December 2011).

31 PBogdanski , JSuliburska , MSzulinska , et al. (2012) Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutr Res 32, 421427.

32 JSuliburska , PBogdanski , MSzulinska , et al. (2012) Effects of green tea supplementation on elements, total antioxidants, lipids, and glucose values in the serum of obese patients. Biol Trace Elem Res 149, 315322.

33 HigginsJPT and GreenS (editors) (2009) Cochrane Handbook for Systematic Reviews of Interventions. Version 5.0.2. New York, NY: Wiley.

34 DMoher , BPham , AJones , et al. (1998) Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet 352, 609613.

35 JPHiggins , SGThompson , JJDeeks , et al. (2003) Measuring inconsistency in meta-analyses. BMJ 327, 557560.

36R DerSimonian & N Laird (1986) Meta-analysis in clinical trials. Control Clin Trials 7, 177188.

37 XXZheng , YLXu , SHLi , et al. (2011) Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomised controlled trials. Am J Clin Nutr 94, 601610.

38 XXZheng , YLXu , SHLi , et al. (2013) Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomised controlled trials. Am J Clin Nutr 97, 750762.

39 DTaubert , RRoesen & ESchömig (2007) Effect of cocoa and tea intake on blood pressure: a meta-analysis. Arch Intern Med 167, 626634.

40 JEBrown , HKhodr , RCHider , et al. (1998) Structural dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties. Biochem J 330, 11731178.

41 NKerry & CRice-Evans (1999) Inhibition of peroxynitrite-mediated oxidation of dopamine by flavonoid and phenolic antioxidants and their structural relationships. J Neurochem 73, 247253.

43 SHIhm , SWJang , ORKim , et al. (2012) Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome. Atherosclerosis 224, 377383.

44N Jochmann , M Lorenz , AV Krosigk , et al. (2008) The efficacy of black tea in ameliorating endothelial function is equivalent to that of green tea. Br J Nutr 99, 863868.

46 MEWidlansky , SJDuffy , NMHamburg , et al. (2005) Effects of black tea consumption on plasma catechins and markers of oxidative stress and inflammation in patients with coronary artery disease. Free Radic Biol Med 38, 499506.

47 RTRas , PLZock & RDraijer (2011) Tea consumption enhances endothelial-dependent vasodilation; a meta-analysis. PLoS ONE 6, e16974.

48 ADeka & JAVita (2011) Tea and cardiovascular disease. Pharmacol Res 64, 136145.

49PK Whelton , J He , LJ Appel , et al. (2002) Primary prevention of hypertension: clinical and public health advisory from the National High Blood Pressure Education Program. JAMA 288, 18821888.

50 DABalentine , SAWiseman & LCBouwens (1997) The chemistry of tea flavonoids. Crit Rev Food Sci Nutr 37, 693704.

51 PPGiggey , CRWendell , ABZonderman , et al. (2011) Greater coffee intake in men is associated with steeper age-related increases in blood pressure. Am J Hypertens 24, 310315.

53G Galati , A Lin , AM Sultan , et al. (2006) Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radic Biol Med 40, 570580.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *