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The effects on glucose metabolism of feeding a high-urea diet to sheep

Published online by Cambridge University Press:  09 March 2007

M. C. Leonard
Affiliation:
Department of Applied Biochemistry and Nutrition, University of Nottingham School of Agriculture, Sutton Bonington, Loughborough, Leics. LE12 5RD
P. J. Buttery
Affiliation:
Department of Applied Biochemistry and Nutrition, University of Nottingham School of Agriculture, Sutton Bonington, Loughborough, Leics. LE12 5RD
D. Lewis
Affiliation:
Department of Applied Biochemistry and Nutrition, University of Nottingham School of Agriculture, Sutton Bonington, Loughborough, Leics. LE12 5RD
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Abstract

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1. Sheep were given either a basal diet of 107 g crude protein (nitrogen × 6.25)/kg or the same diet to which urea was added to increase the crude protein content to 221 g/kg. Isotope-dilution techniques with [U-14C]glucose and [2-3H]glucose were used to measure various criteria of glucose metabolism. The plasma concentrations of urea and potassium were determined. The sheep were then given the alternative diet and the experiment was repeated.

2. Plasma K concentrations were decreased on feeding urea (P < 0.05).

3. Plasma glucose concentrations were reduced on the urea treatment (P < 0.05), while glucose space and metabolic clearance rate were not significantly reduced (P > 0.05).

4. Some implications for the feeding of non-protein-N to ruminants are discussed.

Type
Research Article
Copyright
Copyright © The Nutrition Society 1977

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