1 Xiao, CW (2008) Health effects of soy protein and isoflavones in humans. J Nutr 138, 1244S–1249S.
2 Ma, D-F, Qin, L-Q, Wang, P-Y, et al. (2008) Soy isoflavone intake increases bone mineral density in the spine of menopausal women: meta-analysis of randomized controlled trials. Clin Nutr 27, 57–64.
3 Taku, K, Umegaki, K, Sato, Y, et al. (2007) Soy Isoflavones lower serum total and LDL cholesterol in humans: a meta-analysid of 11 randomized controlled trials. Am J Clin Nutr 85, 1148–1156.
4 Setchell, K, Borriello, S, Hulme, P, et al. (1984) Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease. Am J Clin Nutr 40, 569–578.
5 Setchell, KDR, Brown, NM & Lydeking-Olsen, E (2002) The clinical importance of the metabolite equol – a clue to the effectiveness of soy and its isoflavones. J Nutr 132, 3577–3584.
6 Yuan, J-P, Wang, J-H & Liu, X (2007) Metabolism of dietary soy isoflanoves to equol by human intestinal microflora – implications for health. Mol Nutr Food Res 51, 765–781.
7 Marrian, GF & Haslewood, GAD (1932) Equol, a new inactive phenol isolated from the ketohydroxyoestrin fraction of mares' urine. Biochem J 26, 1227–1232.
8 Millington, AJ, Francis, CM & McKeown, NR (1964) Wether bioassay of animal pasture legumes. II. The oestrogenic activity of nine strains of Trifolium subterraneum L. Aust J Agric Res 15, 527–536.
9 Batterham, TJ, Hart, NK, Lamberton, AJ, et al. (1965) Metabolism of oestrogenic isoflavones in sheep. Nature 206, 509.
10 Shutt, DA & Braden, AWH (1968) The significance of equol in relation to the oestrogenic responses in sheep ingesting clover with a high formononetin content. Aust J Agric Res 19, 545–553.
11 Shutt, DA & Cox, RI (1972) Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro. J Endocrinol 52, 299–310.
12 Bennetts, HW, Uuderwood, EJ & Shier, FL (1946) A specific breeding problem of sheep on subterranean clover pastures in Western Australia. Aust Vet J 22, 2–12.
13 Axelson, M, Kirk, DN, Farrant, RD, et al. (1982) The identification of the weak oestrogen equol [7-hydroxy-3-(4′-hydroxyphenyl)chroman] in human urine. Biochem J 201, 353–357.
14 Setchell, KDR, Clerici, C, Lephart, ED, et al. (2005) S-equol, a potent ligand for estrogen receptor β, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr 81, 1072–1079.
15 Lampe, J, Karr, S, Hutchins, A, et al. (1998) Urinary equol excretion with a soy challenge: Influence of habitual diet. Proc Soc Exp Biol Med 217, 335–339.
16 Rowland, IR, Wiseman, H, Sanders, TA, et al. (2000) Interindividual variation in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora. Nutr Cancer 36, 27–32.
17 Lundh, T (1995) Metabolism of estrogenic isoflavones in domestic animals. Proc Soc Exp Biol Med 208, 33–39.
18 Nilsson, A, Hill, JL & Davies, HL (1967) An in vitro study of formononetin and biochanin A metabolism in rumen fluid from sheep. Biochim Biophys Acta 148, 92–98.
19 Dickinson, JM, Smith, GR, Randel, RD, et al. (1988) In vitro metabolism of formononetin and biochanin a in bovine rumen fluid. J Anim Sci 66, 1969–1973.
20 Hoikkala, A, Mustonen, E, Saastamoinen, I, et al. (2007) High levels of equol in organic skimmed Finnish cow milk. Mol Nutr Food Res 51, 782–786.
21 Mustonen, E, Jokela, T, Saastamoinen, I, et al. (2006) High serum S-equol content in red clover fed ewes: The classical endocrine disruptor is a single enantiomer. Environ Chem Lett 3, 154–159.
22 Davis, AW & Hall, WB (1969) Cyclic change-over designs. Biometrika 56, 283–293.
23 Vanhatalo, A, Pursiainen, P, Kuoppala, K, et al. (2008) . In Biodiversity and Animal Feed Future Challenges for Grassland Production. Grassland Science in Europe, vol. 13, pp. 391–393 [Hopkins, A, Gustafsson, J, Bertilsson, J, Dahlin, G, Nilsdotter-Linde, N and Spörndly, E, editors]. Uppsala: SLU Repro.
24 Sarelli, L, Tuori, M, Saastamoinen, I, et al. (2003) Phytoestrogen content of birdsfoot trefoil and red clover: effects of growth stage and ensiling method. Acta Agric Scand Anim Sci 53, 58–63.
25 Littell, RC, Henry, PR & Ammerman, CB (1998) Statistical analysis of repeated measures data using SAS procedures. J Anim Sci 76, 1216–1231.
26 Steinshamn, H, Purup, S, Thuen, E, et al. (2008) Effects of clover-grass silages and concentrate supplementation on the content of phytoestrogens in dairy cow milk. J Dairy Sci 91, 2715–2725.
27 King, RA, Mano, MM & Head, RJ (1998) Assessment of isoflavonoid concentrations in Australian bovine milk samples. J Dairy Res 65, 479–489.
28 Antignac, JP, Cariou, R, Le Bizec, B, et al. (2003) Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom 17, 1256–1264.
29 Antignac, J, Cariou, R, Bizec, BL, et al. (2004) New data regarding phytoestrogens content in bovine milk. Food Chem 87, 75–81.
31 Braden, AWH, Thain, RI & Shutt, DA (1971) Comparison of plasma phyto-oestrogen levels in sheep and cattle after feeding on fresh clover. Aust J Agric Res 22, 663–670.
32 Lundh, TJ, Pettersson, HI & Martinsson, KA (1990) Comparative levels of free and conjugated plant estrogens in blood plasma of sheep and cattle fed estrogenic silage. J Agric Food Chem 38, 1530–1534.
33 Lundh, TJ, Pettersson, HI & Kiessling, K-H (1988) Liquid chromatographic determination of the estrogens daidezein, formononetin, coumestrol, and equol in bovine blood plasma and urine. J Assoc Off Anal Chem 71, 938–941.