Skip to main content Accessibility help
×
Home

Fish consumption and the incidence of cerebrovascular disease

  • Jukka Montonen (a1), Ritva Järvinen (a2), Antti Reunanen (a1) and Paul Knekt (a1) (a3)

Abstract

Studies of the beneficial role of fish consumption in the prevention of CVD are not consistent in their findings, particularly those studies that focus on the risk of stroke. The aim of the present study is to investigate the relationship between the consumption of different types of fish and the subsequent incidence of cerebrovascular disease (CVA). We prospectively evaluated the association between consumption of different types of fish and CVA in 3958 men and women aged 40–79 years who were free of heart disease and had participated in a health examination survey from 1967 to 1972. A total of 659 incident cases of CVA occurred during a follow-up until the end of 1994. A dietary history interview method provided data on habitual consumption of fish and other foods over the preceding year at baseline. Total fish intake did not predict CVA, but consumption of salted fish suggested an increased risk of intracerebral haemorrhage. The relative risk of intracerebral haemorrhage between the highest tertile of salted fish consumption and non-consumers was 1·98 (95 % CI 1·02, 3·84; P for trend = 0·06) after adjustment for age, sex, energy intake, smoking, BMI, physical activity, geographic area, occupation, diabetes, use of post-menopausal hormones, serum cholesterol, hypertension, and consumptions of butter, vegetables, fruits and berries. The relationship between fish consumption and stroke risk is not straightforward. How the fish is prepared for consumption may play an important role, affecting the association.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Fish consumption and the incidence of cerebrovascular disease
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Fish consumption and the incidence of cerebrovascular disease
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Fish consumption and the incidence of cerebrovascular disease
      Available formats
      ×

Copyright

Corresponding author

*Corresponding author: Dr Jukka Montonen, fax +44 358 9 4744 8924, email jukka.montonen@thl.fi

References

Hide All
1He, K, Song, Y, Daviglus, ML, et al. (2004) Fish consumption and incidence of stroke: a meta-analysis of cohort studies. Stroke 35, 15381542.
2Bouzan, C, Cohen, JT, Connor, WE, et al. (2005) A quantitative analysis of fish consumption and stroke risk. Am J Prev Med 29, 347352.
3Wang, C, Harris, WS, Chung, M, et al. (2006) N-3 fatty acids from fish or fish-oil supplements, but not α-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review. Am J Clin Nutr 84, 517.
4Hooper, L, Thompson, RL, Harrison, RA, et al. (2006) Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. Br Med J 332, 752760.
5Robinson, JG & Stone, NJ (2006) Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids. Am J Cardiol 98, 3949.
6Mozaffarian, D, Longstreth, WT Jr, Lemaitre, RN, et al. (2005) Fish consumption and stroke risk in elderly individuals: the Cardiovascular Health Study. Arch Intern Med 165, 200206.
7Sasaki, S, Zhang, X-H & Kesteloot, H (1995) Dietary sodium, potassium, saturated fat, alcohol, and stroke mortality. Stroke 26, 783789.
8Xie, JX, Sasaki, S, Joossens, JV, et al. (1992) The relationship between urinary cations obtained from the INTERSALT study and cerebrovascular mortality. J Hum Hypertens 6, 1721.
9Cohen, HW, Hailpern, SM, Fang, J, et al. (2006) Sodium intake and mortality in the NHANES II Follow-up Study. Am J Med 119, 275.e277–275.e214.
10Nagata, C, Takatsuka, N, Shimizu, N, et al. (2004) Sodium intake and risk of death from stroke in Japanese men and women. Stroke 35, 15431547.
11Aromaa, A (1981) Epidemiology and Public Health Impact of High Blood Pressure in Finland. Publication of the Social Insurance Institution, AL:17.Helsinki: Social Insurance Institution (in Finnish with an English summary).
12Knekt, P (1988) Serum Alpha-tocopherol and the Risk of Cancer. Publication of the Social Insurance Institution, ML:83.Helsinki: Social Insurance Institution.
13Reunanen, A, Aromaa, A, Pyörälä, K, et al. (1983) The social insurance institution's coronary heart disease study. Baseline data and 5-year mortality experience. Acta Med Scand Suppl 673, 1120.
14Järvinen, R (1996) Epidemiological Follow-up Study on Dietary Antioxidant Vitamins. Results from the Finnish Mobile Clinic Health Examination Survey. Studies in Social Security and Health. no 11. Helsinki: Social Insurance Institution.
15Huang, TC, Chen, CP, Wefler, V, et al. (1961) A stable reagent for the Lieberman–Burchard reaction. Application to rapid serum cholesterol determination. Anal Chem 33, 14051507.
16World Health Organization (1985) Diabetes Mellitus: Report of a WHO Study Group. Geneva: WHO.
17Rastas, M, Seppänen, R, Knuts, L-R, et al. (1989) Nutrient Composition of Foods. Helsinki: Social Insurance Institution.
18Hyvönen, L & Koivistoinen, P (1994) Fatty acid analysis, tag equivalents as net fat value, and nutritional attributes of fish fish products. J Food Composition Anal 7, 4458.
19Hyvönen, L, Lampi, A-M, Varo, P, et al. (1993) Fatty acid analysis, tag equivalents as net fat values, and nutritional attributes of commercial fats and oils. J Food Composition Anal 6, 2440.
20Järvinen, R, Seppänen, R & Knekt, P (1993) Short-term and long-term reproducibility of dietary history interview data. Int J Epidemiol 22, 520527.
21Heliövaara, M, Reunanen, A, Aromaa, A, et al. (1984) Validity of hospital discharge data in a prospective epidemiological study on stroke and myocardial infarction. Acta Med Scand 216, 309315.
22World Health Organization (1967–9) International Classification of Diseases. Manual of International Statistical Classification of Diseases, Injuries, and Causes of Death, 8th rev.Geneva: WHO.
23Cox, D (1972) Regression models and life-tables. J R Stat Soc B 34, 187220.
24He, K, Rimm, EB, Merchant, A, et al. (2002) Fish consumption and risk of stroke in men. JAMA 288, 31303136.
25Iso, H, Rexrode, KM, Stampfer, MJ, et al. (2001) Intake of fish and omega-3 fatty acids and risk of stroke in women. JAMA 285, 304312.
26Sauvaget, C, Nagano, J, Allen, N, et al. (2003) Intake of animal products and stroke mortality in the Hiroshima/Nagasaki Life Span Study. Int J Epidemiol 32, 536543.
27Pietinen, P (1981) Sources of sodium in the Finnish diet. J Sci Agric Soc Finland 53, 275284.
28Chobanian, AV & Hill, M (2000) National heart, lung, and blood institute workshop on sodium and blood pressure: a critical review of current scientific evidence. Hypertension 35, 858863.
29Karppanen, H & Mervaala, E (2006) Sodium intake and hypertension. Prog Cardiovasc Dis 49, 5975.
30Prospective Studies Collaboration (2002) Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360, 19031913.
31Song, YM, Sung, J, Lawlor, DA, et al. (2004) Blood pressure, haemorrhagic stroke, and ischaemic stroke: the Korean national prospective occupational cohort study. Br Med J 328, 324325.
32Prospective Studies Collaboration (2007) Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55 000 vascular deaths. Lancet 370, 18291839.
33Bravata, DM, Wells, CK, Brass, LM, et al. (2007) Dietary fish or seafood consumption is not related to cerebrovascular disease risk in twin veterans. Neuroepidemiology 28, 186190.
34Morris, MC, Manson, JE, Rosner, B, et al. (1995) Fish consumption and cardiovascular disease in the Physicians' Health Study: a prospective study. Am J Epidemiol 142, 166175.
35Myint, PK, Welch, AA, Bingham, SA, et al. (2006) Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC) Norfolk prospective population study. Public Health Nutr 9, 882888.
36Orencia, AJ, Daviglus, ML, Dyer, AR, et al. (1996) Fish consumption and stroke in men: 30-year findings of the Chicago Western Electric Study. Stroke 27, 204209.
37Yang, G, Shu, XO, Jin, F, et al. (2004) Soyfood consumption and risk of glycosuria: a cross-sectional study within the Shanghai women's health study. Eur J Clin Nutr 58, 615620.
38Wennberg, M, Bergdahl, IA, Stegmayr, B, et al. (2007) Fish intake, mercury, long-chain n-3 polyunsaturated fatty acids and risk of stroke in northern Sweden. Br J Nutr 98, 10381045.
39Willett, W (1998) Nutritional Epidemiology. New York: Oxford University Press.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed