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1 MJ Pagliassotti , EC Gayles & JO Hill (1997) Fat and energy balance. Ann N Y Acad Sci 827, 431–448.
2 J Triscari , C Nauss-Karol , BE Levin & AC Sullivan (1985) Changes in lipid metabolism in diet-induced obesity. Metabolism 34, 580–587.
4 LU Thompson , SE Rickard , F Cheung , EO Kenaschuk & WR Obermeyer (1997) Variability in anticancer lignan levels in flaxseed. Nutr Cancer 27, 26–30.
5 SC Cunnane , S Ganguli , C Menard , (1993) High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Br J Nutr 69, 443–453.
6 JR Romans , RC Johnson , DM Wulf , GW Libal & WJ Costello (1995) Effects of ground flaxseed in swine diets on pig performance and on physical and sensory characteristics and omega-3 fatty acid content of pork: I. Dietary level of flaxseed. J Anim Sci 73, 1982–1986.
7 M Axelson , J Sjovall , BE Gustafsson & KD Setchell (1982) Origin of lignans in mammals and identification of a precursor from plants. Nature 298, 659–660.
9 L Wang , J Chen & LU Thompson (2005) The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components. Int J Cancer 116, 793–798.
10 K Prasad (1997) Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed. Mol Cell Biochem 168, 117–123.
11 K Prasad (1999) Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 99, 1355–1362.
12 D Li , JA Yee , LU Thompson & L Yan (1999) Dietary supplementation with secoisolariciresinol diglycoside (SDG) reduces experimental metastasis of melanoma cells in mice. Cancer Lett 142, 91–96.
13 K Prasad (2001) Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat. J Lab Clin Med 138, 32–39.
14 K Prasad , SV Mantha , AD Muir & ND Westcott (2000) Protective effect of secoisolariciresinol diglucoside against streptozotocin-induced diabetes and its mechanism. Mol Cell Biochem 206, 141–149.
16 Y Matsuzawa , T Funahashi & T Nakamura (1999) Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann N Y Acad Sci 892, 146–154.
17 T Yamauchi , J Kamon , H Waki , (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7, 941–946.
18 P Johnsson , A Kamal-Eldin , LN Lundgren & P Aman (2000) HPLC method for analysis of secoisolariciresinol diglucoside in flaxseeds. J Agric Food Chem 48, 5216–5219.
19 J Fritsche , R Angoelal & M Dachtler (2002) On-line liquid-chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry coupling for the separation and characterization of secoisolariciresinol diglucoside isomers in flaxseed. J Chromatogr 972, 195–203.
21 T Shoji , M Kobori , H Shinmoto , A Yanagida , T Kanda & T Tsushida (2000) Inhibitory effects of apple polyphenols on differentiation of 3T3-L1 cells into adipocytes. Food Sci Technol Res 6, 119–121.
22 DJ Dyck , GJ Heigenhauser & CR Bruce (2006) The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity. Acta Physiol (Oxf) 186, 5–16.
23 M Armoni , N Kritz , C Harel , F Bar-Yoseph , H Chen , MJ Quon & E Karnieli (2003) Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. J Biol Chem 278, 30614–30623.
24 AN Hollenberg , VS Susulic , JP Madura , B Zhang , DE Moller , P Tontonoz , P Sarraf , BM Spiegelman & BB Lowell (1997) Functional antagonism between CCAAT/enhancer binding protein-alpha and peroxisome proliferator-activated receptor-gamma on the leptin promoter. J Biol Chem 272, 5283–5290.
25 M Iwaki , M Matsuda , N Maeda , T Funahashi , Y Matsuzawa , M Makishima & I Shimomura (2003) Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52, 1655–1663.
26 BP Kota , TH Huang & BD Roufogalis (2005) An overview on biological mechanisms of PPARs. Pharmacol Res 51, 85–94.
27 N Marx , H Duez , JC Fruchart & B Staels (2004) Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells. Circ Res 94, 1168–1178.
30 SJ Bhathena , AA Ali , C Haudenschild , (2003) Dietary flaxseed meal is more protective than soy protein concentrate against hypertriglyceridemia and steatosis of liver in an animal model of obesity. J Am Coll Nutr 22, 157–164.
31 HJ Kim , M Takahashi & O Ezaki (1999) Fish oil feeding decreases mature sterol regulatory element-binding protein 1 (SREBP-1) by down-regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs. J Biol Chem 274, 25892–25898.
32 H Fujita , H Fujishima , J Koshimura , M Hosoba , N Yoshioka , T Shimotomai , T Morii , T Narita , M Kakei & S Ito (2005) Effects of antidiabetic treatment with metformin and insulin on serum and adipose tissue adiponectin levels in db/db mice. Endocr J 52, 427–433.
33 NF Brown , JK Hill , V Esser , JL Kirkland , BE Corkey , DW Foster & JD McGarry (1997) Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. Biochem J 327, Pt 1, 225–231.
35 T Clavel , G Henderson , W Engst , J Dore & M Blaut (2006) Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside. FEMS Microbiol Ecol 55, 471–478.
36 JM Lehmann , LB Moore , TA Smith-Oliver , WO Wilkison , TM Willson & SA Kliewer (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270, 12953–12956.