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Foetal plasma magnesium levels during maternal hypo- or hypermagnesaemia in ewes

Published online by Cambridge University Press:  09 March 2007

J.-P. Barlet ,
Marie-Jeanne Davicco ,
Michèle Moncaup  and
J. Lefaivre
J.-P. Barlet
Affiliation:
INRA Theix, 63110 Beaumont, France
Marie-Jeanne Davicco
Affiliation:
INRA Theix, 63110 Beaumont, France
Michèle Moncaup
Affiliation:
INRA Theix, 63110 Beaumont, France
J. Lefaivre
Affiliation:
INRA Theix, 63110 Beaumont, France
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Abstract

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1. The influence of maternal hypo- or hypermagnesaemia of foetal plasma magnesium levels was studied in pregnant ewes between the 120th and the 145th day of gestation using a permanent catheter inserted in utero into the left aorta of the foetus on the 115th day of gestation.

2. In seven ewes, carrying eleven foetuses, the injection of 1 α-hydroxycholecalciferol induced a hypomagnesaemia which lasted 72 h. This had no significant effect on foetal plasma Mg levels.

3. In five ewes, carrying six foetuses, hypermagnesaemia induced by a 2 h magnesium chloride infusion had no significant effect on foetal plasma Mg levels.

4. These results provide evidence that in sheep during the last 20 d of gestation the foetal regulation of plasma Mg is independent of the maternal plasma Mg levels.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 42 , Issue 3 , November 1979 , pp. 559 - 566
Copyright
Copyright © The Nutrition Society 1979

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