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The influence of high-carbohydrate meals with different glycaemic indices on substrate utilisation during subsequent exercise

Published online by Cambridge University Press:  09 March 2007

Ching-Lin Wu ,
Ceri Nicholas ,
Clyde Williams ,
Alison Took  and
Lucy Hardy
Ching-Lin Wu
Affiliation:
Sports and Exercise Nutrition Research Group, School of Sport and Exercise Sciences, Loughborough University, Leicester, UK
Ceri Nicholas
Affiliation:
Sports and Exercise Nutrition Research Group, School of Sport and Exercise Sciences, Loughborough University, Leicester, UK
Clyde Williams*
Affiliation:
Sports and Exercise Nutrition Research Group, School of Sport and Exercise Sciences, Loughborough University, Leicester, UK
Alison Took
Affiliation:
Sports and Exercise Nutrition Research Group, School of Sport and Exercise Sciences, Loughborough University, Leicester, UK
Lucy Hardy
Affiliation:
Sports and Exercise Nutrition Research Group, School of Sport and Exercise Sciences, Loughborough University, Leicester, UK
*
*Corresponding author: Professor Clyde Williams, fax +44 1509 226300, email C.Williams@lboro.ac.uk
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Abstract

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The present study was designed to examine the effects of mixed high-carbohydrate meals with different glycaemic indices (GI) on substrate utilization during subsequent exercise. Nine healthy male recreational runners (age 26·8 (sem 1·1) years, body mass 74·7 (sem 2·4) kg, V˙O2max 58·1 (sem 1·7) ml/kg per min) completed three trials: high-glycaemic-index meal (HGI), low-glycaemic-index meal (LGI) and fasting (FAST), separated by 7 d. The test meals contained 2 g carbohydrate/kg body mass, they were isoenergetic and the GI values were 77·4, 36·9 and 0·0 respectively. In each trial, subjects consumed the test meal 3 h before performing a 60 min run at 65 % V˙O2max on a motorized treadmill. Ingestion of the HGI and LGI resulted in hyperglycaemia and hyperinsulinaemia during the postprandial period compared with the FAST (P<0·05). The incremental area under the curve for plasma glucose was 2-fold higher for HGI compared with LGI (108·7 v. 48·9 mmol/l per min). In contrast, plasma non-esterified fatty acid concentrations were significantly lower following HGI and LGI compared with FAST (P<0·05). During the subsequent submaximal exercise, plasma glucose declined to below the fasting value in HGI compared with LGI and FAST (P<0·05). The estimated total fat oxidation was significantly higher for the LGI than the HGI during exercise (P<0·05). In summary, both pre-exercise carbohydrate meals resulted in lower rates of fat oxidation during subsequent exercise than when subjects performed exercise in the fasting state. However, the LGI resulted in a higher rate of fat oxidation during exercise than following the consumption of the HGI.

Keywords

GlucoseInsulinFat oxidationCarbohydrate oxidation

Information

Type
Research Article
Information
British Journal of Nutrition , Volume 90 , Issue 6 , December 2003 , pp. 1049 - 1056
Copyright
Copyright © The Nutrition Society 2003

References

Achten, J, Gleeson, M & Jeukendrup, AE (2002) Determination of the exercise intensity that elicits maximal fat oxidation. Med Sci Sports Exerc 34, 92–97.CrossRefGoogle ScholarPubMed
Bjorck, I, Liljeberg, H & Ostman, E (2000) Low glycaemic-index foods. Br J Nut 83, Suppl. 1 S149–S155.CrossRefGoogle ScholarPubMed
Borg, GA (1973) Perceived exertion: a note on "history" and methods. Med Sci Sports 5, 90–93.Google ScholarPubMed
Burke, LM, Collier, GR, Beasley, SK, et al. . (1995) Effect of coingestion of fat and protein with carbohydrate feedings on muscle glycogen storage. J Appl Physiol 78, 2187–2192.CrossRefGoogle ScholarPubMed
Coulston, AM, Hollenbeck, CB, Liu, GC, et al. . (1984a) Effect of source of dietary carbohydrate on plasma glucose, insulin, and gastric inhibitory polypeptide responses to test meals in subjects with noninsulin-dependent diabetes mellitus. Am J Clin Nutr 40, 965–970.CrossRefGoogle ScholarPubMed
Coulston, AM, Hollenbeck, CB & Reaven, GM (1984b) Utility of studies measuring glucose and insulin responses to various carbohydrate-containing foods. Am J Clin Nutr 39, 163–167.CrossRefGoogle ScholarPubMed
Coyle, EF, Jeukendrup, AE, Wagenmakers, AJ & Saris, WH (1997) Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. Am J Physiol 273, E268–E275.Google ScholarPubMed
Decombaz, DS, Arnaud, MJ, Thelin, AL, Schurch, P & Howald, H (1985) Oxidation and metabolic effects of fructose or glucose ingested before exercise. Int J Sports Med 6, 282–286.CrossRefGoogle ScholarPubMed
DeMarco, HM, Sucher, KP, Cisar, CJ & Butterfield, GE (1999) Pre-exercise carbohydrate meals: application of glycemic index. Med Sci Sports Exerc 31, 164–170.CrossRefGoogle ScholarPubMed
Dill, DB & Costill, DL (1974) Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 37, 247–248.CrossRefGoogle ScholarPubMed
Febbraio, MA, Chiu, A, Angus, DJ, Arkinstall, MJ & Hawley, JA (2000a) Effects of carbohydrate ingestion before and during exercise on glucose kinetics and performance. J Appl Physiol 89, 2220–2226.CrossRefGoogle ScholarPubMed
Febbraio, MA, Keenan, J, Angus, DJ, Campbell, SE & Garnham, AP (2000b) Preexercise carbohydrate ingestion, glucose kinetics, and muscle glycogen use: effect of the glycemic index. J Appl Physiol 89, 1845–1851.CrossRefGoogle ScholarPubMed
Febbraio, MA & Stewart, KL (1996) CHO feeding before prolonged exercise: effect of glycemic index on muscle glycogenolysis and exercise performance. J Appl Physiol 81, 1115–1120.CrossRefGoogle ScholarPubMed
Fielding, RA, Costill, DL, Fink, WJ, King, DS, Kovaleski, JE & Kirwan, JP (1987) Effects of pre-exercise carbohydrate feedings on muscle glycogen use during exercise in well-trained runners. Eur J Appl Physiol Occup Physiol 56, 225–229.CrossRefGoogle ScholarPubMed
Foster-Powell, K & Miller, JB (1995) International table of glycaemic index. Am J Clin Nutr 62, 871S–890S.CrossRefGoogle Scholar
Frayn, KN (1983) Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 55, 628–634.CrossRefGoogle ScholarPubMed
Hargreaves, M, Costill, DL, Fink, WJ, King, DS & Fielding, RA (1987) Effect of pre-exercise carbohydrate feedings on endurance cycling performance. Med Sci Sports Exerc 19, 33–36.CrossRefGoogle ScholarPubMed
Hollenbeck, CB, Coulston, AM & Reaven, GM (1988) Comparison of plasma glucose and insulin responses to mixed meals of high-, intermediate-, and low-glycemic potential. Diabetes Care 11, 323–329.CrossRefGoogle ScholarPubMed
Horowitz, JF, Mora-Rodriguez, R, Byerley, LO & Coyle, EF (1997) Lipolytic suppression following carbohydrate ingestion limits fat oxidation during exercise. Am J Physiol 273, E768–E775.Google ScholarPubMed
Ivy, JL, Lee, MC, Brozinick, JT Jr & Reed, MJ (1988) Muscle glycogen storage after different amounts of carbohydrate ingestion. J Appl Physiol 65, 2018–2023.CrossRefGoogle ScholarPubMed
Jenkins, DJ, Wolever, TM & Taylor, RH (1981) Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 34, 362–366.CrossRefGoogle Scholar
Kirwan, JP, Cyr-Campbell, D, Campbell, WW, Scheiber, J & Evans, WJ (2001a) Effects of moderate and high glycemic index meals on metabolism and exercise performance. Metab Clin Exp 50, 849–855.CrossRefGoogle ScholarPubMed
Kirwan, JP, O'Gorman, DJ, Cyr-Campbell, D, Campbell, WW, Yarasheski, KE & Evans, WJ (2001b) Effects of a moderate glycemic meal on exercise duration and substrate utilization. Med Sci Exerc 33, 1517–1523.CrossRefGoogle ScholarPubMed
Laurell, S & Tibbling, G (1966) An enzymatic fluorometric micromethod for the determination of glycerol. Clin Chim Acta 13, 317–322.CrossRefGoogle ScholarPubMed
Maughan, RJ (1982) A simple, rapid method for the determination of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20-μl blood sample. Clin Chim Acta 122, 231–240.CrossRefGoogle ScholarPubMed
Murray, R, Paul, GL, Seifert, JG, Eddy, DE & Halaby, GA (1989a) The effects of glucose, fructose, and sucrose ingestion during exercise. Med Sci Sports Exerc 21, 275–282.CrossRefGoogle ScholarPubMed
Murray, R, Seifert, JG, Eddy, DE, Paul, GL & Halaby, GA (1989b) Carbohydrate feeding and exercise: effect of beverage carbohydrate content. Eur J Appl Physiol Occup Physiol 59, 152–158.CrossRefGoogle ScholarPubMed
Nilsson, LH & Hultman, E (1973) Liver glycogen in man – the effect of total starvation or a carbohydrate-poor diet followed by carbohydrate refeeding. Scand J Clin Lab Invest 32, 325–330.CrossRefGoogle ScholarPubMed
Sparks, MJ, Selig, SS & Febbraio, MA (1998) Pre-exercise carbohydrate ingestion: effect of the glycemic index on endurance exercise performance. Med Sci Sports Exerc 30, 844–849.Google ScholarPubMed
Stannard, SR, Constantini, NW & Miller, JC (2000) The effect of glycemic index on plasma glucose and lactate levels during incremental exercise. Int J Sport Nutr Exerc Metab 10, 51–61.CrossRefGoogle ScholarPubMed
Tarnopolsky, MA, Bosman, M, Macdonald, JR, Vandeputte, D, Martin, J & Roy, BD (1997) Postexercise protein–carbohydrate and carbohydrate supplements increase muscle glycogen in men and women. J Appl Physiol 83, 1877–1883.CrossRefGoogle ScholarPubMed
Thomas, DE, Brotherhood, JR & Brand, JC (1991) Carbohydrate feeding before exercise: effect of glycemic index. Int J Sports Med 12, 180–186.CrossRefGoogle ScholarPubMed
Thomas, DE, Brotherhood, JR & Miller, JB (1994) Plasma glucose levels after prolonged strenuous exercise correlate inversely with glycemic response to food consumed before exercise. Int J Sport Nutr 4, 361–373.CrossRefGoogle ScholarPubMed
Ventura, JL, Estruch, A, Rodas, G & Segura, R (1994) Effect of prior ingestion of glucose or fructose on the performance of exercise of intermediate duration. Eur J Appl Physiol Occup Physiol 68, 345–349.CrossRefGoogle ScholarPubMed
Wee, SL, Williams, C, Gray, S & Horabin, J (1999) Influence of high and low glycemic index meals on endurance running capacity. Med Sci Sports Exerc 31, 393–399.CrossRefGoogle ScholarPubMed
Williams, C, Nute, MG, Broadbank, L & Vinall, S (1990) Influence of fluid intake on endurance running performance. A comparison between water, glucose and fructose solutions. Eur J Appl Physiol Occup Physiol 60, 112–119.CrossRefGoogle ScholarPubMed
Wolever, TM & Bolognesi, C (1996) Prediction of glucose and insulin responses of normal subjects after consuming mixed meals varying in energy, protein, fat, carbohydrate and glycemic index. J Nutr 126, 2807–2812.Google ScholarPubMed
Wolever, TM & Jenkins, DJ (1986) The use of the glycemic index in predicting the blood glucose response to mixed meals. Am J Clin Nutr 43, 167–172.CrossRefGoogle ScholarPubMed