Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 13
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Baker, Ella J. Miles, Elizabeth A. Burdge, Graham C. Yaqoob, Parveen and Calder, Philip C. 2016. Metabolism and Functional Effects of Plant-Derived Omega-3 Fatty Acids in Humans. Progress in Lipid Research,


    Pappas, Apostolos Liakou, Aikaterini and Zouboulis, Christos C. 2016. Nutrition and skin. Reviews in Endocrine and Metabolic Disorders,


    Barcelos, Raquel C.S. de Mello-Sampayo, Cristina Antoniazzi, Caren T.D. Segat, Hecson J. Silva, Henrique Veit, Juliana C. Piccolo, Jaqueline Emanuelli, Tatiana Bürger, Marilise E. Silva- Lima, Beatriz and Rodrigues, Luis M. 2015. Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model. Journal of Dermatological Science, Vol. 79, Issue. 3, p. 298.


    Hu, Lizhi Man, Huibin Elias, Peter M. and Man, Mao-Qiang 2015. Herbal medicines that benefit epidermal permeability barrier function. Dermatologica Sinica, Vol. 33, Issue. 2, p. 90.


    Muggli, Reto 2015. Cosmeceuticals and Active Cosmetics, Third Edition.


    Asadi-Samani, Majid Bahmani, Mahmoud and Rafieian-Kopaei, Mahmoud 2014. The chemical composition, botanical characteristic and biological activities of Borago officinalis: a review. Asian Pacific Journal of Tropical Medicine, Vol. 7, p. S22.


    Kim, Kyu-Bong Nam, Yoon A. Kim, Hyung Sik Hayes, A. Wallace and Lee, Byung-Mu 2014. α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation. Food and Chemical Toxicology, Vol. 70, p. 163.


    Kimoto-Nira, H. Nagakura, Y. Kodama, C. Shimizu, T. Okuta, M. Sasaki, K. Koikawa, N. Sakuraba, K. Suzuki, C. and Suzuki, Y. 2014. Effects of ingesting milk fermented by Lactococcus lactis H61 on skin health in young women: A randomized double-blind study. Journal of Dairy Science, Vol. 97, Issue. 9, p. 5898.


    Park, Kui Young Ko, Eun Jung Kim, In Su Li, Kapsok Kim, Beom Joon Seo, Seong Jun Kim, Myeung Nam and Hong, Chang Kwun 2014. The Effect of Evening Primrose Oil for the Prevention of Xerotic Cheilitis in Acne Patients Being Treated with Isotretinoin: A Pilot Study. Annals of Dermatology, Vol. 26, Issue. 6, p. 706.


    Kimoto-Nira, Hiromi Aoki, Reiji Sasaki, Keisuke Suzuki, Chise and Mizumachi, Koko 2012. Oral intake of heat-killed cells of Lactococcus lactis strain H61 promotes skin health in women. Journal of Nutritional Science, Vol. 1,


    2012. Scientific Opinion on the substantiation of a health claim related to a combination of flaxseed oil and vitamin E and maintenance of the skin permeability barrier function pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA Journal, Vol. 10, Issue. 7, p. 2819.


    Levy, Joseph and Sharoni, Yoav 2011. Formulating, Packaging, and Marketing of Natural Cosmetic Products.


    Pappas, Apostolos 2009. The relationship of diet and acne. Dermato-Endocrinology, Vol. 1, Issue. 5, p. 262.


    ×

Intervention with flaxseed and borage oil supplements modulates skin condition in women

  • Silke De Spirt (a1), Wilhelm Stahl (a1), Hagen Tronnier (a2), Helmut Sies (a1), Marie Bejot (a3), Jean-Marc Maurette (a3) and Ulrike Heinrich (a2)
  • DOI: http://dx.doi.org/10.1017/S0007114508020321
  • Published online: 02 September 2008
Abstract

Ingestion of selected nutrients modulates dermal properties. In the present study, two groups of women ingested flaxseed or borage oil for 12 weeks. The control group received a placebo containing medium-chain fatty acids. Dose was 2·2 g total fatty acids/d with α-linolenic acid and linoleic acid as major constituents in the flaxseed oil group; in the borage oil group linoleic and γ-linolenic acid were predominant. In the flaxseed oil group, the contribution of α-linolenic acid to total fatty acids in plasma was significantly increased on weeks 6 and 12, whereas there was an increase in γ-linolenic acid in the borage oil group (P < 0·05). Skin irritation was performed by nicotinate treatment, and changes in skin reddening and blood flow were monitored. Compared to week 0, skin reddening was diminished in both groups; blood flow was also lowered. Skin hydration was significantly increased after 12 weeks of treatment compared to week 0, with flaxseed or borage oil (P < 0·05). Transepidermal water loss was decreased in both oil groups by about 10 % after 6 weeks of supplementation. A further decrease was determined after 12 weeks in the flaxseed oil group. Surface evaluation of living skin revealed that roughness and scaling of the skin were significantly decreased with flaxseed and borage oil comparing week 0 and week 12 (P < 0·05). Except for hydration, none of the parameters was affected in the placebo group. The present data provide evidence that skin properties can be modulated by an intervention with dietary lipids.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Intervention with flaxseed and borage oil supplements modulates skin condition in women
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Intervention with flaxseed and borage oil supplements modulates skin condition in women
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Intervention with flaxseed and borage oil supplements modulates skin condition in women
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Professor Dr Wilhelm Stahl, fax +49 211 811 3029, email wilhelm.stahl@uni-duesseldorf.de
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1F Afaq & H Mukhtar (2006) Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Exp Dermatol 15, 678684.

2H Sies & W Stahl (2004) Nutritional protection against skin damage from sunlight. Annu Rev Nutr 24, 173200.

4W Stahl , U Heinrich , O Aust , H Tronnier & H Sies (2006) Lycopene-rich products and dietary photoprotection. Photochem Photobiol Sci 5, 238242.

5LE Rhodes , S O'Farrell , MJ Jackson & PS Friedmann (1994) Dietary fish-oil supplementation in humans reduces UVB-erythemal sensitivity but increases epidermal lipid peroxidation. J Invest Dermatol 103, 151154.

6HS Black & LE Rhodes (2006) The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. Cancer Detect Prev 30, 224232.

8O Rosella , A Sinclair & PR Gibson (2000) Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro. J Gastroenterol Hepatol 15, 626631.

9S Pepe (2005) Effect of dietary polyunsaturated fatty acids on age-related changes in cardiac mitochondrial membranes. Exp Gerontol 40, 751758.

10E Proksch , WM Holleran , GK Menon , PM Elias & KR Feingold (1993) Barrier function regulates epidermal lipid and DNA synthesis. Br J Dermatol 128, 473482.

11VA Ziboh , Y Cho , I Mani & S Xi (2002) Biological significance of essential fatty acids/prostanoids/lipoxygenase-derived monohydroxy fatty acids in the skin. Arch Pharm Res 25, 747758.

12T Brosche & D Platt (2000) Effect of borage oil consumption on fatty acid metabolism, transepidermal water loss and skin parameters in elderly people. Arch Gerontol Geriatr 30, 139150.

13SY Hou , AK Mitra , SH White , GK Menon , R Ghadially & PM Elias (1991) Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction. J Invest Dermatol 96, 215223.

15U Heinrich , U Koop , MC Leneveu-Duchemin , (2003) Multicenter comparison of skin hydration in terms of physical-, physiological- and product-dependent parameters by the capacitive method (Corneometer CM 825). Int J Cosm Sci 25, 4553.

17G Primavera & E Berardesca (2005) Sensitive skin: mechanism and diagnosis. Int J Cosmet Sci 27, 110.

18LM Rodrigues , PC Pinto , JM Magro , M Fernandes & J Alves (2004) Exploring the influence of skin perfusion on transepidermal water loss. Skin Res Techn 10, 257262.

19H Tronnier , M Wiebusch , U Heinrich & R Stute (1999) Surface evaluation of living skin. Adv Exp Med Biol 455, 507516.

21GC Burdge & PC Calder (2005) Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod Nutr Dev 45, 581597.

23J Ren & SH Chung (2007) Anti-inflammatory effect of α-linolenic acid and its mode of action through inhibition of nitric oxide production and inducible nitric oxide synthase gene expression via NF-κB and mitogen-activated protein kinase pathway. J Agric Food Chem 55, 50735080.

24MM Dooper , B van Riel , YM Graus & L M'Rabet (2003) Dihomo-gamma-linolenic acid inhibits tumour necrosis factor-alpha production by human leucocytes independently of cyclooxygenase activity. Immunology 110, 348357.

25R Muggli (2005) Systemic evening primrose oil improves the biophysical skin parameters of healthy adults. Int J Cosm Sci 27, 243249.

26PW Wertz , W Abraham , ES Cho & DT Downing (1986) Linoleate- rich o-acylsphingolipids of mammalian epidermis: structures and effects of essential fatty acid deficiency. Prog Lipid Res 25, 383389.

27V Schreiner , GS Gooris , S Pfeiffer , G Lanzendörfer , H Wenck , W Diembeck , E Proksch & J Bouwstra (2000) Barrier characteristics of different human skin types investigated with X-ray diffraction, lipid analysis, and electron microscopy imaging. J Invest Dermatol 114, 654660.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: