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    Thompson, Amanda L. Monteagudo-Mera, Andrea Cadenas, Maria B. Lampl, Michelle L. and Azcarate-Peril, M. A. 2015. Milk- and solid-feeding practices and daycare attendance are associated with differences in bacterial diversity, predominant communities, and metabolic and immune function of the infant gut microbiome. Frontiers in Cellular and Infection Microbiology, Vol. 5,


    Lawrence, Robert M. and Pane, Camille A. 2007. Human Breast Milk: Current Concepts of Immunology and Infectious Diseases. Current Problems in Pediatric and Adolescent Health Care, Vol. 37, Issue. 1, p. 7.


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Intestinal microflora of human infants and current trends for its nutritional modulation

  • Konstantinos C. Mountzouris (a1) (a2), Anne L. McCartney (a1) and Glenn R. Gibson (a1)
  • DOI: http://dx.doi.org/10.1079/BJN2002563
  • Published online: 01 March 2007
Abstract

Diet, among other environmental and genetic factors, is currently recognised to have an important role in health and disease. There is increasing evidence that the human colonic microbiota can contribute positively towards host nutrition and health. As such, dietary modulation has been proposed as important for improved gut health, especially during the highly sensitive stage of infancy. Differences in gut microflora composition and incidence of infection occur between breast- and formula-fed infants. Human milk components that cannot be duplicated in infant formulae could possibly account for these differences. However, various functional food ingredients such as oligosaccharides, prebiotics, proteins and probiotics could effect a beneficial modification in the composition and activities of gut microflora of infants. The aim of the present review is to describe existing knowledge on the composition and metabolic activities of the gastrointestinal microflora of human infants and discuss various possibilities and opportunities for its nutritional modulation.

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Copyright
Corresponding author
*Corresponding author: Dr G. R. Gibson, fax +44 118 9357222, email g.r.gibson@reading.ac.uk
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