1. Kafeshani, O, Sarrafzadegan, N, Nouri, F, et al. (2015) Major dietary patterns in Iranian adolescents: Isfahan Healthy Heart Program, Iran. ARYA Atheroscler
2. Mesirow, MS & Welsh, JA (2015) Changing beverage consumption patterns have resulted in fewer liquid calories in the diets of US children: National Health and Nutrition Examination Survey 2001–2010. J Acad Nutr Diet 115, 559–566.
3. Kar, S & Khandelwal, B (2015) Fast foods and physical inactivity are risk factors for obesity and hypertension among adolescent school children in east district of Sikkim, India. J Nat Sci Biol Med 6, 356–359.
4. Pigeot, I, Barba, G, Chadjigeorgiou, C, et al. (2009) Prevalence and determinants childhood overweight and obesity in European countries: pooled analysis of the existing surveys within the IDEFICS Consortium.
Int J Obes (Lond) 33, 1103–1110.
5. World Health Organization (2012) Population-Based Approaches To Childhood Obesity Prevention. Geneva: WHO Library Cataloguing-in-Publication Data, WHO Document Production Services.
6. Ogden, CL, Carroll, MD, Kit, BK, et al. (2014) Prevalence of childhood and adult obesity in the United States, 2011–2012. J Am Med Assoc 311, 806–814.
7. Scholz-Ahrens, KE, Ade, P, Marten, B, et al. (2007) Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. J Nutr 137, 838S–846S.
8. Ortiz, LT, Rodriguez, ML, Alzueta, C, et al. (2009) Effect of inulin on growth performance, intestinal tract sizes, mineral retention and tibial bone mineralisation in broiler chickens. Br Poult Sci 50, 325–332.
9. Weaver, CM, Martin, BR, Story, JA, et al. (2010) Novel fibers increase bone calcium content and strength beyond efficiency of large intestine fermentation. J Agric Food Chem 58, 8952–8957.
10. Pouyamanesh, Z, Amoli, MM, Yaghmaei, P, et al. (2016) Effect of inulin supplementation in male mice fed with high fat diet on biochemical profile and α-amylase gene expression. Trop J Pharm Res 15, 1197–1203.
11. Yasuda, K, Roneker, KR, Miller, DD, et al. (2006) Supplemental dietary inulin affects the bioavailability of iron in corn and soybean meal to young pigs. J Nutr 136, 3033–3038.
12. Watzl, B, Girrbach, S & Roller, M (2005) Inulin, oligofructose and immunomodulation. Br J Nutr 93, 49S–55S.
13. Roberfroid, MB, Cumps, J & Devogelaer, JP (2002) Dietary chicory inulin increases whole-body bone mineral density in growing male rats. J Nutr 132, 3599–3602.
14. Jolliff, JS & Mahan, DC (2012) Effect of dietary inulin and phytase on mineral digestibility and tissue retention in weanling and growing swine. J Anim Sci 90, 3012–3022.
15. Demigné, C, Jacobs, H, Moundras, C, et al. (2008) Comparison of native or reformulated chicory fructans, or non-purified chicory, on rat cecal fermentation and mineral metabolism. Eur J Nutr 47, 366–374.
16. Aigner, B, Renner, S, Kessler, B, et al. (2010) Transgenic pigs as models for translational biomedical research. J Mol Med 88, 653–664.
17. Pearce, AI, Richards, RG, Milz, S, et al. (2007) Animal models for implant biomaterial research in bone: a review. Eur Cell Mater 13, 1–10.
18. Reinwald, S & Burr, D (2008) Review of nonprimate, large animal models for osteoporosis research. J Bone Miner Res 23, 1353–1368.
19. Nutrient Requirements of Swine (2012) Committee on Nutrient Requirements of Swine, Board on Agriculture and Natural Resources, Division on Earth and Life Studies, 11th rev. ed. Washington, DC: National Academies Press.
20. Estrada, A, Drew, MD & Van Kessel, A (2001) Effect of the dietary supplementation of fructooligosaccharides and Bifidobacterium longum to early-weaned pigs on performance and fecal bacterial populations. Can J Anim Sci 81, 141–148.
21. Kjos, NP, Øverland, M, Fauske, AK, et al. (2010) Feeding chicory inulin to entire male pigs during the last period before slaughter reduces skatole in digesta and backfat. Livest Sci 134, 143–145.
22. Salinas, MV, Hamet, MF, Binaghi, J, et al. (2017) Calcium–inulin wheat bread: prebiotic effect and bone mineralisation in growing rats. Int J Food Sci Tech 52, 2463–2470.
23. Peressini, D & Sensidoni, A (2009) Effect of soluble dietary fibre addition on rheological and breadmaking properties of wheat doughs. J Cereal Sci 49, 190–201.
24. Commission Regulation (EU) (2010) Regulation (EC) No 1924/2006 of the European Parliament and of the Council with regard to the list of nutrition claims. No. 116/2010, Commission Regulation (EU), Brussels, 9 February.
25. Skiba, G, Weremko, D, Sobol, M, et al. (2015) Bone mineralisation of weaned piglets fed a diet free of inorganic phosphorus and supplemented with phytase, as assessed by dual-energy X-ray absorptiometry. Arch Anim Nutr 69, 267–275.
26. Ferretti, JL, Capozza, RF, Mondelo, N, et al. (1993) Interrelationships between densitometric, geometric and mechanical properties of rat femora: inferences concerning mechanical regulation of bone modelling. J Bone Miner Res 8, 1389–1396.
27. Horwitz, W & Latimer, GW (editors) (2011)
Official Methods of Analysis of AOAC International, Current through Revision 4, 18th ed. Gaithersburg, MD: AOAC International.
28. Folch, J, Lees, M & Sloane Stanley, GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226, 497–509.
29. Grela, ER, Pietrzak, K, Sobolewska, S, et al. (2013) Effect of inulin and garlic supplementation in pig diets. Ann Anim Sci 13, 63–71.
30. Bielohuby, M, Matsuura, M, Herbach, N, et al. (2010) Short-term exposure to low-carbohydrate, high-fat diets induces low bone mineral density and reduces bone formation in rats. J Bone Miner Res 25, 275–284.
31. Cao, JJ, Sun, L & Gao, H (2010) Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice. Ann NY Acad Sci 1192, 292–297.
32. Fehrendt, H, Linn, T, Hartmann, S, et al. (2014) Negative influence of a long-term high-fat diet on murine bone architecture. Int J Endocrinol 2014, 318924.
33. Yanagihara, GR, Shimano, RC, Tida, JA, et al. (2017) Influence of high-fat diet on bone tissue: An experimental study in growing rats. J Nutr Health Aging 21, 1337–1343.
34. Griel, AE, Kris-Etherton, PM, Hilpert, KF, et al. (2007) An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans. Nutr J 6, 2.
35. Duan, Y, An, Y, Li, N, et al. (2013) Multiple univariate data analysis reveals the inulin effects on the high-fat-diet induced metabolic alterations in rat myocardium and testicles in the preobesity state. J Proteome Res 12, 3480–3495.
36. Kumar, SA, Ward, LC & Brown, L (2016) Inulin oligofructose attenuates metabolic syndrome in high-carbohydrate, high-fat diet-fed rats. Br J Nutr 116, 1502–1511.
37. Devareddy, L, Khalil, DA, Korlagunta, K, et al. (2006) The effects of fructo-oligosaccharides in combination with soy protein on bone in osteopenic ovariectomized rats. Menopause 13, 692–699.
38. Jamieson, JA, Ryz, NR, Taylor, CG, et al. (2008) Dietary long-chain inulin reduces abdominal fat but has no effect on bone density in growing female rats. Br J Nutr 100, 451–459.
39. Abrams, SA, Griffin, IJ, Hawthorne, KM, et al. (2005) A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr 82, 471–476.
40. Abrams, SA, Hawthorne, KM, Aliu, O, et al. (2007) An inulin-type fructan enhances calcium absorption primarily via an effect on colonic absorption in humans. J Nutr 137, 2208–2212.
41. Wang, Y, Dellatore, P, Douard, V, et al. (2016) High fat diet enriched with saturated, but not monounsaturated fatty acids adversely affects femur, and both diets increase calcium absorption in older female mice. Nutr Res 36, 742–750.
42. Kruger, MC, Brown, KE, Collett, G, et al. (2003) The effect of fructooligosaccharides with various degrees of polymerization on calcium bioavailability in the growing rat.
Exp Biol Med (Maywood) 228, 683–688.
43. Kaur, N & Gupta, K (2002) Applications of inulin and oligofructose in health and nutrition. J Biosci 27, 703–714.
44. Roberfroid, MB & Delzenne, N (1998) Dietary fructans. Annu Rev Nutr 18, 117–143.
45. Scharrer, E & Lutz, T (1991) Effects of short fatty acids on calcium absorption by rat colon. Exp Physiol 76, 615–618.
46. Oh, SR, Sul, OJ, Kim, YY, et al. (2010) Saturated fatty acids enhance osteoclast survival. J Lipid Res 51, 892–899.
47. Estadella, D, da Penha Oller do Nascimento, CM, Oyama, LM, et al. (2013) Lipotoxicity: effects of dietary saturated and transfatty acids. Mediators Inflamm 2013, 137579.
48. Patsch, JM, Kiefer, FW, Varga, P, et al. (2011) Increased bone resorption and impaired bone microarchitecture in short-term and extended high-fat diet–induced obesity. Metabolism 60, 243–249.
49. Parhami, F, Tintut, Y, Beamer, WG, et al. (2001) Atherogenic high-fat diet reduces bone mineralization in mice. J Bone Miner Res 16, 182–188.
50. Zhong, X, Xiu, L, Wei, G, et al. (2011) Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway. Int J Mol Med 28, 535–542.