1Bazzano LA, He J, Ogden LG, et al. (2002) Fruit and vegetable intake and risk of cardiovascular disease in US adults: the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Am J Clin Nutr 76, 93–99.
2Ross R (1999) Atherosclerosis – an inflammatory disease. N Engl J Med 340, 115–126.
3Steinberg D, Parthasarathy S, Carew TE, et al. (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320, 915–924.
4Ames BN, Shigenaga MK & Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A 90, 7915–7922.
5Asplund K (2002) Antioxidant vitamins in the prevention of cardiovascular disease: a systematic review. J Intern Med 251, 372–392.
6Clarke R & Armitage J (2002) Antioxidant vitamins and risk of cardiovascular disease. Review of large-scale randomised trials. Cardiovasc Drugs Ther 16, 411–415.
7Vivekananthan DP, Penn MS, Sapp SK, et al. (2003) Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 361, 2017–2023.
8Eidelman RS, Hollar D, Hebert PR, et al. (2004) Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease. Arch Intern Med 164, 1552–1556.
9Helmersson J, Vessby B, Larsson A, et al. (2004) Association of type 2 diabetes with cyclooxygenase-mediated inflammation and oxidative stress in an elderly population. Circulation 109, 1729–1734.
10Bergström S (1967) Prostaglandins: members of a new hormonal system. These physiologically very potent compounds of ubiquitous occurrence are formed from essential fatty acids. Science 157, 382–391.
11Vane JR (1976) Prostaglandins as mediators of inflammation. Adv Prostaglandin Thromboxane Res 2, 791–801.
12Willoughby DA (1975) Heberden Oration, 1974. Human arthritis applied to animal models. Towards a better therapy. Ann Rheum Dis 34, 471–478.
13Mutschler DK, Eriksson MB, Wikström BG, et al. (2003) Microdialysis-evaluated myocardial cyclooxygenase-mediated inflammation and early circulatory depression in porcine endotoxemia. Crit Care Med 31, 1780–1785.
14Samuelsson B (1973) Quantitative aspects on prostaglandin synthesis in man. Adv Biosci 9, 7–14.
15Basu S (1998) Radioimmunoassay of 15-keto-13,14-dihydro-prostaglandin F2α: an index for inflammation via cyclooxygenase catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids 58, 347–352.
16Basu S & Eriksson M (1998) Oxidative injury and survival during endotoxemia. FEBS Lett 438, 159–160.
17Morrow JD, Hill KE, Burk RF, et al. (1990) A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci U S A 87, 9383–9387.
18Shishehbor MH, Zhang R, Medina H, et al. (2006) Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease. Free Radic Biol Med 41, 1678–1683.
19Basu S & Helmersson J (2005) Factors regulating isoprostane formation in vivo. Antioxid Redox Signal 7, 221–235.
20Helmersson J, Ärnlöv J, Vessby B, et al. (2005) Serum selenium predicts levels of F2-isoprostanes and prostaglandin F2α in a 27 year follow-up study of Swedish men. Free Radic Res 39, 763–770.
21Hedstrand H (1975) A study of middle-aged men with particular reference to risk factors for cardiovascular disease. Ups J Med Sci Suppl 19, 1–61.
22Smedman AE, Gustafsson IB, Berglund LG, et al. (1999) Pentadecanoic acid in serum as a marker for intake of milk fat: relations between intake of milk fat and metabolic risk factors. Am J Clin Nutr 69, 22–29.
23Basu S (1998) Radioimmunoassay of 8-iso-prostaglandin F2α: an index for oxidative injury via free radical catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids 58, 319–325.
24Helmersson J & Basu S (1999) F2-isoprostane excretion rate and diurnal variation in human urine. Prostaglandins Leukot Essent Fatty Acids 61, 203–205.
25Basu S (2007) Novel cyclooxygenase-catalyzed bioactive prostaglandin F2α from physiology to new principles in inflammation. Med Res Rev 27, 435–468.
26Helmersson J, Vessby B, Larsson A, et al. (2005) Cyclooxygenase-mediated prostaglandin F2α is decreased in an elderly population treated with low-dose aspirin. Prostaglandins Leukot Essent Fatty Acids 72, 227–233.
27Smedman A, Vessby B & Basu S (2004) Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by α-tocopherol and cyclo-oxygenase-2 inhibitor. Clin Sci (Lond) 106, 67–73.
28Basu S, Lee R, Dunster C, et al. (2004) . In Proceedings of the New York Academy of Science: Vitamin E and Health, p. P11. New York: New York Academy of Science.
29Szeto YT, Kwok TC & Benzie IF (2004) Effects of a long-term vegetarian diet on biomarkers of antioxidant status and cardiovascular disease risk. Nutrition 20, 863–866.
30van Herpen-Broekmans WM, Klopping-Ketelaars IA, Bots ML, et al. (2004) Serum carotenoids and vitamins in relation to markers of endothelial function and inflammation. Eur J Epidemiol 19, 915–921.
31Ford ES, Liu S, Mannino DM, et al. (2003) C-reactive protein concentration and concentrations of blood vitamins, carotenoids, and selenium among United States adults. Eur J Clin Nutr 57, 1157–1163.
32Wannamethee SG, Lowe GD, Rumley A, et al. (2006) Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. Am J Clin Nutr 83, 567–574, .
33McMillan DC, Talwar D, Sattar N, et al. (2002) The relationship between reduced vitamin antioxidant concentrations and the systemic inflammatory response in patients with common solid tumours. Clin Nutr 21, 161–164.
34Chang CY, Chen JY, Ke D, et al. (2005) Plasma levels of lipophilic antioxidant vitamins in acute ischemic stroke patients: correlation to inflammation markers and neurological deficits. Nutrition 21, 987–993.
35Block G, Jensen C, Dietrich M, et al. (2004) Plasma C-reactive protein concentrations in active and passive smokers: influence of antioxidant supplementation. J Am Coll Nutr 23, 141–147.
36Upritchard JE, Sutherland WH & Mann JI (2000) Effect of supplementation with tomato juice, vitamin E, and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes. Diabetes Care 23, 733–738.
37Tahir M, Foley B, Pate G, et al. (2005) Impact of vitamin E and C supplementation on serum adhesion molecules in chronic degenerative aortic stenosis: a randomized controlled trial. Am Heart J 150, 302–306.
38Bruunsgaard H, Poulsen HE, Pedersen BK, et al. (2003) Long-term combined supplementations with α-tocopherol and vitamin C have no detectable anti-inflammatory effects in healthy men. J Nutr 133, 1170–1173.
39Erlinger TP, Guallar E, Miller ER III, et al. (2001) Relationship between systemic markers of inflammation and serum α-carotene levels. Arch Intern Med 161, 1903–1908.
40Hu P, Reuben DB, Crimmins EM, et al. (2004) The effects of serum β-carotene concentration and burden of inflammation on all-cause mortality risk in high-functioning older persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci 59, 849–854.
41Sanchez-Moreno C, Cano MP, de Ancos B, et al. (2004) Consumption of high-pressurized vegetable soup increases plasma vitamin C and decreases oxidative stress and inflammatory biomarkers in healthy humans. J Nutr 134, 3021–3025.
42Roberts L J II, Oates JA, Linton MF, et al. (2007) The relationship between dose of vitamin E and suppression of oxidative stress in humans. Free Radic Biol Med 43, 1388–1393.
43Dietrich M, Block G, Hudes M, et al. (2002) Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers. Cancer Epidemiol Biomarkers Prev 11, 7–13.
44Reilly M, Delanty N, Lawson JA, et al. (1996) Modulation of oxidant stress in vivo in chronic cigarette smokers. Circulation 94, 19–25.
45Mayne ST, Walter M, Cartmel B, et al. (2004) Supplemental β-carotene, smoking, and urinary F2-isoprostane excretion in patients with prior early stage head and neck cancer. Nutr Cancer 49, 1–6.
46Basu S (2006) F2-isoprostane induced prostaglandin formation in the rabbit. Free Radic Res 40, 273–277.
47Chan PH, Yurko M & Fishman RA (1982) Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices. J Neurochem 38, 525–531.
48Rao GN, Runge MS & Alexander RW (1995) Hydrogen peroxide activation of cytosolic phospholipase A2 in vascular smooth muscle cells. Biochim Biophys Acta 1265, 67–72.
49Senftleben U & Karin M (2002) The IKK/NF-κB pathway. Crit Care Med 30, S18–S26.
50Becker W & Pearson M (2002) Kostvanor och Näringsintag i Sverige 1997–1998. Metod och Resultatanalys (Food Habits and Nutrients in Sweden 1997–1998. Method and Results Analysis). Uppsala, Sweden: Swedish National Food Administration.