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Mild dehydration impairs cognitive performance and mood of men


The present study assessed the effects of mild dehydration on cognitive performance and mood of young males. A total of twenty-six men (age 20·0 (sd 0·3) years) participated in three randomised, single-blind, repeated-measures trials: exercise-induced dehydration plus a diuretic (DD; 40 mg furosemide); exercise-induced dehydration plus placebo containing no diuretic (DN); exercise while maintaining euhydration plus placebo (EU; control condition). Each trial included three 40 min treadmill walks at 5·6 km/h, 5 % grade in a 27·7°C environment. A comprehensive computerised six-task cognitive test battery, the profile of mood states questionnaire and the symptom questionnaire (headache, concentration and task difficulty) were administered during each trial. Paired t tests compared the DD and DN trials resulting in >1 % body mass loss (mean 1·59 (sd 0·42) %) with the volunteer's EU trial (0·01 (sd 0·03) %). Dehydration degraded specific aspects of cognitive performance: errors increased on visual vigilance (P = 0·048) and visual working memory response latency slowed (P = 0·021). Fatigue and tension/anxiety increased due to dehydration at rest (P = 0·040 and 0·029) and fatigue during exercise (P = 0·026). Plasma osmolality increased due to dehydration (P < 0·001) but resting gastrointestinal temperature was not altered (P = 0·238). In conclusion, mild dehydration without hyperthermia in men induced adverse changes in vigilance and working memory, and increased tension/anxiety and fatigue.

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*Corresponding author: Dr L. E. Armstrong, fax +1 860 486 1123, email
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1VM Sharma , K Sridharan , G Pichan , (1986) Influence of heat-stress induced dehydration on mental functions. Ergonomics 29, 791799.

2PM Gopinathan , G Pichan & VM Sharma (1988) Role of dehydration in heat stress-induced variations in mental performance. Arch Environ Health 43, 1517.

3C Cian , PA Barraud , B Melin , (2001) Effects of fluid ingestion on cognitive function after heat stress or exercise-induced dehydration. Int J Psychophysiol 42, 243251.

5PD Tomporowski , K Beasman , MS Ganio , (2007) Effects of dehydration and fluid ingestion on cognition. Int J Sports Med 28, 891896.

6C Cian , N Koulmann , PA Barraud , (2000) Influence of variations in body hydration on cognitive function: effect of hyperhydration, heat stress, and exercise-induced dehydration. J Psychophysiol 14, 2936.

7G Szinnai , H Schachinger , MJ Arnaud , (2005) Effect of water deprivation on cognitive-motor performance in healthy men and women. Am J Physiol Regul Integr Comp Physiol 289, R275R280.

9HR Lieberman (2007) Hydration and cognition: a critical review and recommendations for future research. J Am Coll Nutr 26, 555S561S.

10HR Lieberman , WJ Tharion , B Shukitt-Hale , (2002) Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Psychopharmacology (Berl) 164, 250261.

13DB Cook , PJ O'Connor , SA Eubanks , (1997) Naturally occurring muscle pain during exercise: assessment and experimental evidence. Med Sci Sports Exerc 29, 9991012.

16BJ Fine , JL Kobrick , HR Lieberman , (1994) Effects of caffeine or diphenhydramine on visual vigilance. Psychopharmacology (Berl) 114, 233238.

17CA Olson , JA Thornton , GE Adam , (2010) Effects of two adenosine antagonists, quercetin and caffeine, on vigilance and mood. J Clin Psychopharmacol 30, 573578.

19DB Miller & JP O'Callaghan (2006) The pharmacology of wakefulness. Metabolism 55, S13S19.

20KA Ellis & PJ Nathan (2001) The pharmacology of human working memory. Int J Neuropsychopharmacol 4, 299313.

21NK Popova , LN Ivanova , TG Amstislavskaya , (2001) Brain serotonin metabolism during water deprivation and hydration in rats. Neurosci Behav Physiol 31, 327332.

22HR Lieberman , BP Coffey & J Kobrick (1998) A vigilance task sensitive to the effects of stimulants, hypnotics and environmental stress – The Scanning Visual Vigilance Test. Behav Res Methods Instrum Comput 30, 416422.

23DF Dinges & JW Powell (1985) Microcomputer analyses of performance on a portable, simple, visual RT task during sustained operations. Behav Res Methods Instrum Comput 17, 652655.

24B Shukitt-Hale , EW Askew & HR Lieberman (1997) Effects of 30 days of undernutrition on reaction time, moods, and symptoms. Physiol Behav 62, 783789.

26AD Baddeley (1968) A 3 min reasoning test based on grammatical transformation. Psychon Sci 10, 341342.

28LE Banderet & HR Lieberman (1989) Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Res Bull 22, 759762.

30LE Armstrong , RW Kenefick , JW Castellani , (1997) Bioimpedance spectroscopy technique: intra-, extracellular, and total body water. Med Sci Sports Exerc 29, 16571663.

14HR Lieberman , GP Bathalon , CM Falco , (2005) Severe decrements in cognition function and mood induced by sleep-loss, heat, dehydration and undernutrition during simulated combat. Biol Psychiatry 57, 422429.

33WD Crews Jr, DW Harrison & JW Wright (2008) A double-blind, placebo-controlled, randomized trial of the effects of dark chocolate and cocoa on variables associated with neuropsychological functioning and cardiovascular health: clinical findings from a sample of healthy, cognitively intact older adults. Am J Clin Nutr 87, 872880.

34RC Gordon , MC Rose , SA Skeaff , (2009) Iodine supplementation improves cognition in mildly iodine-deficient children. Am J Clin Nutr 90, 12641271.

36KE D'Anci , A Vibhakar , JH Kanter , (2009) Voluntary dehydration and cognitive performance in trained college athletes. Percept Mot Skills 109, 251269.

37B Shukitt-Hale , MJ Stillman , BE Marlowe , (1994) Hypobaric hypoxia impairs spatial memory in an exposure-dependent fashion. Behav Neural Biol 62, 244252.

38B Shukitt-Hale , LE Banderet & HR Lieberman (1998) Elevation-dependent symptom, mood, and performance changes produced by exposure to hypobaric hypoxia. Int J Aviat Psychol 8, 319334.

39S Di & JG Tasker (2004) Dehydration-induced synaptic plasticity in magnocellular neurons of the hypothalamic supraoptic nucleus. Endocrinology 145, 51415149.

40CY Wang , WL Haskell , SW Farrell , (2010) Cardiorespiratory fitness levels among US adults 20–49 years of age: findings from the 1999–2004 National Health and Nutrition Examination Survey. Am J Epidemiol 171, 426435.

41MN Sawka , SN Cheuvront & R Carter (2005) Human water needs. Nutr Rev 63, S30S39.

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