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No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial – comments by Zhang and Li

  • Jian Zhang (a1) and Yanfeng Li (a2)
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      No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial – comments by Zhang and Li
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      No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial – comments by Zhang and Li
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      No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial – comments by Zhang and Li
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References
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1Richardson, AJ (2008) n-3 Fatty acids and mood: the devil is in the detail. Br J Nutr 99, 221223.
2Rogers, PJ, Appleton, KM, Kessler, D, Peters, TJ, Gunnell, D, Hayward, RC, Heatherley, SV, Christian, LM, McNaughton, SA & Ness, AR (2008) No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial. Br J Nutr 99, 421431.
3Stoll, AL, Severus, WE, Freeman, MP, Rueter, S, Zboyan, HA, Diamond, E, Cress, KK & Marangell, LB (1999) Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Arch Gen Psychiatry 56, 407412.
4Su, KP, Shen, WW, Huang, SY, Stoll, AL, Damico, KE, Marangell, LB & Severus, WE (2000) Are ω3 fatty acids beneficial in depression but not mania? Arch Gen Psychiatry 57, 716717.
5Puri, BK, Richardson, AJ, Stoll, AL, Marangell, L & Severus, WE (2000) The effects of olive oil on ω3 fatty acids and mood disorders. Arch Gen Psychiatry 57, 715.
6Logan, AC (2005) Omega-3 and depression research: hold the olive oil. Prostaglandins Leukot Essent Fatty Acids 72, 441.
7Menendez, JA, Papadimitropoulou, A, Vellon, L & Lupu, R (2006) A genomic explanation connecting “Mediterranean diet”, olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory “PEA3 transcription factor-PEA3 DNA binding site” complexes at the Her-2/neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells. Eur J Cancer 42, 24252432.
8Menendez, JA, Vellon, L, Colomer, R & Lupu, R (2005) Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification. Ann Oncol 16, 359371.
9Pacheco, YM, Lopez, S, Bermudez, B, Abia, R, Villar, J & Muriana, FJ (2008) A meal rich in oleic acid beneficially modulates postprandial sICAM-1 and sVCAM-1 in normotensive and hypertensive hypertriglyceridemic subjects. J Nutr Biochem 19, 200205.
10Pacheco, YM, Bermudez, B, Lopez, S, Abia, R, Villar, J & Muriana, FJ (2006) Ratio of oleic to palmitic acid is a dietary determinant of thrombogenic and fibrinolytic factors during the postprandial state in men. Am J Clin Nutr 84, 342349.
11Silvers, KM, Woolley, CC, Hamilton, FC, Watts, PM & Watson, RA (2005) Randomised double-blind placebo-controlled trial of fish oil in the treatment of depression. Prostaglandins Leukot Essent Fatty Acids 72, 211218.
12Grenyer, BF, Crowe, T, Meyer, B, Owen, AJ, Grigonis-Deane, EM, Caputi, P & Howe, PR (2007) Fish oil supplementation in the treatment of major depression: a randomised double-blind placebo-controlled trial. Prog Neuropsychopharmacol Biol Psychiatry 31, 13931396.
13Appleton, KM, Hayward, RC, Gunnell, D, Peters, TJ, Rogers, PJ, Kessler, D & Ness, AR (2006) Effects of n-3 long-chain polyunsaturated fatty acids on depressed mood: systematic review of published trials. Am J Clin Nutr 84, 13081316.
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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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